Selected Publications

Fluorescent lung slice

Selected publications from our laboratory.

  1. Mehaffey JH, Charles, EJ, Narahari AK, Schubert S, Laubach VE, Teman NR, Lynch KR, Kron IL, and Sharma AK. Increasing circulating sphingosine-1-phosphate attenuates lung injury during ex vivo lung perfusion.J Thorac Cardiovasc Surg. 2018 Aug;156(2):910-917
  2. Stone ML, Zhao Y, Smith JR, Weiss M, Kron IL, Laubach VE, Sharma AK. Mesenchymal stromal cell-derived extracellular vesicles attenuate lung ischemia-reperfusion injury and enhance reconditioning of donor lungs after circulatory death.Respir Res.2017 Dec 21;18(1):212 [PMCID: PMC5740880]
  3. Sharma AK, LaPar DJ, Stone ML, Zhao Y, Mehta CK, Kron IL, and Laubach VE. NOX2 activation of NKT cells is blocked by adenosine A2A receptor to inhibit lung reperfusion injury. Am J Respir Crit Care Med., 2016 [PMCID: PMC4872653]
  4. Ex vivo perfusion techniques: state of the art and potential applications. Cypel M, Neyrinck A, Machuca TN. Intensive Care Med. 2019 Mar;45(3):354-356
  5. The Impact of Donor and Recipient Age: Older Lung Transplant Recipients Do Not Require Younger Lungs. Hall DJ, Jeng EI, Gregg JA, Pelaez A, Emtiazjoo AM, Chandrashekaran S, Pipkin M, Beaver TM, Machuca TN. Ann Thorac Surg. 2019 Mar;107(3):868-876
  6. Sharma AK, Mulloy DP, Le LT and Laubach VE. NADPH oxidase mediates synergistic effects of IL-17 and TNF-α on CXCL1 expression by epithelial cells after lung ischemia-reperfusion.Am J Physiol Lung Cell Mol Physiol, 306(1):L69-79; 2014 [PMCID: PMC3920214]
  7. Sharma AK, LaPar DJ, Stone, ML, Zhao Y, Kron IL, Laubach VE. Receptor for advanced glycation end products (RAGE) on iNKT cells mediates lung ischemia-reperfusion injury. Am J Transplant,13(9):2255-67, 2013 [PMCID: PMC3776006]
  8. Sharma AK, LaPar DJ, Zhao Y, Li L, Lau CL, Kron IL, Iwakura Y, Okusa MD, and Laubach VE. Natural killer T cell-derived IL-17 mediates lung ischemia-reperfusion injury. Am J Respir Crit Care Med183(11):1539-49, 2011 [PMCID: PMC3137143]
  9. LaPar DJ, Laubach VE, Emaminia A, Crosby IK, Sharma AK, Sumner HM, Webb DV, Lau CL, and Kron IL. Pretreatment strategy with adenosine A2A receptor agonist attenuates reperfusion injury in a preclinical porcine lung transplantation model. J Thorac Cardiovasc Surg142(4):887-94, 2011 [PMCID: PMC3212732]
  10. Anvari F, Sharma AK, Fernandez LG, Hranjec T, Ravid K, Kron IL and Laubach VE. Tissue-derived pro-inflammatory effect of adenosine A2B receptor in lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg140:871-7, 2010 [PMCID: PMC2943004]
  11. Sharma AK, Laubach VE, Ramos SI, Zhao Y, Linden J, Kron IL, and Yang Z. Adenosine A2A receptor activation on CD4+ T lymphocytes and neutrophils attenuates lung ischemia-reperfusion injury. J Thorac Cardiovasc Surg 139(2):474-482, 2010 [PMCID: PMC2813368]
  12. Sharma AK, Linden J, Kron IL, Laubach VE. Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation. Respir Res10:58, 2009 [PMCID: PMC2711962]