Kerri A O'Malley

Kerri A O'Malley, PhD

Assistant Professor

Department: MD-SURGERY-VASCULAR
Business Phone: (352) 273-5318
Business Email: komalley@ufl.edu

Teaching Profile

Courses Taught
2015
GMS6683 Fundamentals of Vascular Physiology and Pathology
2024
BMS6632 Endo and Reproduction
2024
GMS7877 Responsible Conduct of Biomedical Research

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-3844-9861

Publications

2023
Activation of the Aryl Hydrocarbon Receptor in Muscle Exacerbates Ischemic Pathology in Chronic Kidney Disease.
Circulation research. 133(2):158-176 [DOI] 10.1161/CIRCRESAHA.123.322875. [PMID] 37325935.
2023
Chronic activation of the aryl hydrocarbon receptor in muscle exacerbates ischemic pathology in chronic kidney disease.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2023.05.16.541060. [PMID] 37292677.
2023
N-acetylcysteine treatment attenuates hemodialysis access-related limb pathophysiology in mice with chronic kidney disease.
American journal of physiology. Renal physiology. 325(3):F271-F282 [DOI] 10.1152/ajprenal.00083.2023. [PMID] 37439200.
2023
Single-Nuclei RNA-Sequencing of the Gastrocnemius Muscle in Peripheral Artery Disease.
Circulation research. 133(10):791-809 [DOI] 10.1161/CIRCRESAHA.123.323161. [PMID] 37823262.
2023
Temporal serum metabolomic and lipidomic analyses distinguish patients with access-related hand disability following arteriovenous fistula creation.
Scientific reports. 13(1) [DOI] 10.1038/s41598-023-43664-z. [PMID] 37798334.
2022
A Murine Model of Hemodialysis Access-related Hand Dysfunction.
Journal of visualized experiments : JoVE. (183) [DOI] 10.3791/63892. [PMID] 35723470.
2022
Influences of renal insufficiency and ischemia on mitochondrial bioenergetics and limb dysfunction in a novel murine iliac arteriovenous fistula model.
JVS-vascular science. 3:345-362 [DOI] 10.1016/j.jvssci.2022.10.001. [PMID] 36439698.
2022
Interventional- and amputation-stage muscle proteomes in the chronically threatened ischemic limb.
Clinical and translational medicine. 12(1) [DOI] 10.1002/ctm2.658. [PMID] 35073463.
2022
Metabolomic profiling reveals muscle metabolic changes following iliac arteriovenous fistula creation in mice.
American journal of physiology. Renal physiology. 323(5):F577-F589 [DOI] 10.1152/ajprenal.00156.2022. [PMID] 36007889.
2022
Temporal Dynamics of the Intestinal Microbiome Following Short-Term Dietary Restriction.
Nutrients. 14(14) [DOI] 10.3390/nu14142785. [PMID] 35889742.
2021
Development of a murine iliac arteriovenous fistula model for examination of hemodialysis access-related limb pathophysiology.
JVS-vascular science. 2:247-259 [DOI] 10.1016/j.jvssci.2021.09.022. [PMID] 34816137.
2021
Skeletal myopathy in CKD: a comparison of adenine-induced nephropathy and 5/6 nephrectomy models in mice.
American journal of physiology. Renal physiology. 321(1):F106-F119 [DOI] 10.1152/ajprenal.00117.2021. [PMID] 34121452.
2021
Unique Metabolomic Profile of Skeletal Muscle in Chronic Limb Threatening Ischemia.
Journal of clinical medicine. 10(3) [DOI] 10.3390/jcm10030548. [PMID] 33540726.
2019
Chronic kidney disease exacerbates ischemic limb myopathy in mice via altered mitochondrial energetics.
Scientific reports. 9(1) [DOI] 10.1038/s41598-019-52107-7. [PMID] 31664123.
2018
Hyperacute Monocyte Gene Response Patterns Are Associated With Lower Extremity Vein Bypass Graft Failure.
Circulation. Genomic and precision medicine. 11(3) [DOI] 10.1161/CIRCGEN.117.001970. [PMID] 29530886.
2017
Hemodynamic Influence on Smooth Muscle Cell Kinetics and Phenotype During Early Vein Graft Adaptation.
Annals of biomedical engineering. 45(3):644-655 [DOI] 10.1007/s10439-016-1725-0. [PMID] 27624660.
2017
Pilot assessment of a human extracellular matrix-based vascular graft in a rabbit model.
Journal of vascular surgery. 65(3):839-847.e1 [DOI] 10.1016/j.jvs.2016.02.046. [PMID] 27139784.
2016
Systemic inflammation as a predictor of clinical outcomes after lower extremity angioplasty/stenting.
Journal of vascular surgery. 64(3):766-778.e5 [DOI] 10.1016/j.jvs.2015.04.399. [PMID] 26054584.
2015
Time and flow-dependent changes in the p27(kip1) gene network drive maladaptive vascular remodeling.
Journal of vascular surgery. 62(5):1296-302.e2 [DOI] 10.1016/j.jvs.2014.05.015. [PMID] 24953896.
2014
Flow reversal promotes intimal thickening in vein grafts.
Journal of vascular surgery. 60(2):471-478.e1 [DOI] 10.1016/j.jvs.2013.06.081. [PMID] 24342069.
2011
Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage.
Laboratory investigation; a journal of technical methods and pathology. 91(12):1787-95 [DOI] 10.1038/labinvest.2011.94. [PMID] 21931299.
2011
Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling.
Journal of immunology (Baltimore, Md. : 1950). 187(2):911-8 [DOI] 10.4049/jimmunol.1100588. [PMID] 21690321.
2011
Sepsis induces early alterations in innate immunity that impact mortality to secondary infection.
Journal of immunology (Baltimore, Md. : 1950). 186(1):195-202 [DOI] 10.4049/jimmunol.1002104. [PMID] 21106855.
2008
Danger Signaling Dependent Mechanisms in Flow-Induced Arterial Remodeling
Arteriosclerosis Thrombosis and Vascular Biology. 28
2008
Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes.
Hepatology (Baltimore, Md.). 47(5):1725-36 [DOI] 10.1002/hep.22187. [PMID] 18311843.
2008
Myd88-Dependent Pathway Initiates Neointimal Hyperplasia Development Independently of Tlr4
Circulation. 118
2007
Genomic and proteomic determinants of lower extremity revascularization failure: rationale and study design.
Journal of vascular surgery. 45 Suppl A(Suppl A):A82-91 [PMID] 17544028.
2007
Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis.
Shock (Augusta, Ga.). 28(6):675-683 [PMID] 17621256.
2007
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis.
The Journal of experimental medicine. 204(6):1463-74 [PMID] 17548519.
2006
Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis.
Journal of immunology (Baltimore, Md. : 1950). 177(11):7943-9 [PMID] 17114466.
2006
Interleukin-6 and STAT3 protect the liver from hepatic ischemia and reperfusion injury during ischemic preconditioning.
Surgery. 140(5):793-802 [PMID] 17084723.
2006
Interleukin-6: Still crazy after all these years.
Critical care medicine. 34(10):2690-1 [PMID] 16983274.
2005
CD11c+ dendritic cells are required for survival in murine polymicrobial sepsis.
Journal of immunology (Baltimore, Md. : 1950). 175(5):3282-6 [PMID] 16116220.
2004
Stem cell fusion confusion.
Experimental hematology. 32(2):131-4 [PMID] 15102472.

Grants

Aug 2022 – Jul 2023
VA IPA for Kerri O'Malley
Role: Principal Investigator
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Sep 2018 – Aug 2019
VA IPA – CSP599 Kerri O'Malley
Role: Principal Investigator
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Aug 2013 – Dec 2019
Constitutive and Agent-Based Multiscale Models to Improve Vein Graft Survival
Role: Co-Investigator
Funding: NATL INST OF HLTH NHLBI

Contact Details

Phones:
Business:
(352) 273-5318
Emails:
Business:
komalley@ufl.edu
Addresses:
Business Mailing:
PO Box 100128
GAINESVILLE FL 32610
Business Street:
1601 SW ARCHER RD
Room E597
VA MEDICAL CENTER ROOM
GAINESVILLE FL 32608