Scott A Berceli

Scott A Berceli, MD, PhD

Robert H. And Kathleen M. Axline Basic Science Professor And Vice Chair Of Research

Department: MD-SURGERY-VASCULAR
Business Phone: (352) 548-6441
Business Email: bercesa@surgery.ufl.edu

Teaching Profile

Courses Taught
2016,2018-2019
BME7979 Advanced Research
2018
MDC6001 Intro Clin Practice
2018
MDC7600 Surgery Clerkship
2017-2018
BME7980 Research for Doctoral Dissertation
2018
EML7979 Advanced Research
2017
BME6971 Research for Master’s Thesis
2015
GMS6683 Fundamentals of Vascular Physiology and Pathology
2022-2024
BMS4905 Medical Sciences Senior Research

Board Certifications

  • Vascular Surgery
    American Board of Surgery

Clinical Profile

Subspecialties
  • Vascular Surgery

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-2257-0111

Publications

2024
Arteriovenous Fistula Histology, Hemodynamics, and Wall Mechanics: A Case Report of Successful and Failed Access in a Single Patient.
Kidney medicine. 6(4) [DOI] 10.1016/j.xkme.2024.100801. [PMID] 38562969.
2024
Limited health literacy is common among vascular surgery patients.
Surgery. [DOI] 10.1016/j.surg.2024.02.003. [PMID] 38461121.
2024
Mitochondrial targeted catalase improves muscle strength following arteriovenous fistula creation in mice with chronic kidney disease.
Scientific reports. 14(1) [DOI] 10.1038/s41598-024-58805-1. [PMID] 38594299.
2023
Activation of the Aryl Hydrocarbon Receptor in Muscle Exacerbates Ischemic Pathology in Chronic Kidney Disease.
Circulation research. 133(2):158-176 [DOI] 10.1161/CIRCRESAHA.123.322875. [PMID] 37325935.
2023
Assessing the quality of reporting of studies using Vascular Quality Initiative (VQI) data.
Journal of vascular surgery. 77(1):248-255 [DOI] 10.1016/j.jvs.2022.06.024. [PMID] 35760240.
2023
Association of Shear Stress with Subsequent Lumen Remodeling in Hemodialysis Arteriovenous Fistulas.
Clinical journal of the American Society of Nephrology : CJASN. 18(1):72-83 [DOI] 10.2215/CJN.04630422. [PMID] 36446600.
2023
Chronic activation of the aryl hydrocarbon receptor in muscle exacerbates ischemic pathology in chronic kidney disease.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2023.05.16.541060. [PMID] 37292677.
2023
Distinct Temporal Pattern of the Prediction of Lumen Remodeling of Lower Extremity Vein Bypass Grafts by Initial Local Hemodynamics.
Annals of biomedical engineering. 51(2):296-307 [DOI] 10.1007/s10439-022-03019-7. [PMID] 35881266.
2023
N-acetylcysteine treatment attenuates hemodialysis access-related limb pathophysiology in mice with chronic kidney disease.
American journal of physiology. Renal physiology. 325(3):F271-F282 [DOI] 10.1152/ajprenal.00083.2023. [PMID] 37439200.
2023
National Institutes of Health funding among vascular surgeons is rare.
Journal of vascular surgery. 78(4):845-851 [DOI] 10.1016/j.jvs.2023.05.052. [PMID] 37327950.
2023
National Treatment Patterns and Outcomes for Hospitalized Patients with Chronic Limb-Threatening Ischemia and End-Stage Kidney Disease.
Vascular and endovascular surgery. 57(4):357-364 [DOI] 10.1177/15385744221146868. [PMID] 36541126.
2023
Non-invasive estimation of the parameters of a three-element windkessel model of aortic arch arteries in patients undergoing thoracic endovascular aortic repair.
Frontiers in bioengineering and biotechnology. 11 [DOI] 10.3389/fbioe.2023.1127855. [PMID] 36926690.
2023
Photochemically Aided Arteriovenous Fistula Creation to Accelerate Fistula Maturation.
International journal of molecular sciences. 24(8) [DOI] 10.3390/ijms24087571. [PMID] 37108733.
2023
Predicting 1-year in-stent restenosis in superficial femoral arteries through multiscale computational modelling
Journal of The Royal Society Interface. 20(201) [DOI] 10.1098/rsif.2022.0876. [PMID] 37015267.
2023
Single-Nuclei RNA-Sequencing of the Gastrocnemius Muscle in Peripheral Artery Disease
Circulation Research. 133(10):791-809 [DOI] 10.1161/circresaha.123.323161.
2023
Social Vulnerability Is Associated With Higher Rates of Hospitalizations and Amputations for Peripheral Arterial Disease.
The American journal of cardiology. 203:463-465 [DOI] 10.1016/j.amjcard.2023.07.063. [PMID] 37542956.
2023
Temporal serum metabolomic and lipidomic analyses distinguish patients with access-related hand disability following arteriovenous fistula creation.
Scientific reports. 13(1) [DOI] 10.1038/s41598-023-43664-z. [PMID] 37798334.
2022
A Murine Model of Hemodialysis Access-related Hand Dysfunction.
Journal of visualized experiments : JoVE. (183) [DOI] 10.3791/63892. [PMID] 35723470.
2022
A predictive multiscale model of in-stent restenosis in femoral arteries: linking haemodynamics and gene expression with an agent-based model of cellular dynamics.
Journal of the Royal Society, Interface. 19(188) [DOI] 10.1098/rsif.2021.0871. [PMID] 35350882.
2022
Differential hemodynamics between arteriovenous fistulas with or without intervention before successful use.
Frontiers in cardiovascular medicine. 9 [DOI] 10.3389/fcvm.2022.1001267. [PMID] 36407418.
2022
Dynamic Remodeling of Human Arteriovenous Fistula Wall Obtained From Magnetic Resonance Imaging During the First 6 Months After Creation.
Kidney international reports. 7(8):1905-1909 [DOI] 10.1016/j.ekir.2022.05.016. [PMID] 35967120.
2022
Functional analysis of arteriovenous fistulae in non-contrast magnetic resonance images
Computer Methods and Programs in Biomedicine. 222 [DOI] 10.1016/j.cmpb.2022.106938.
2022
Influences of renal insufficiency and ischemia on mitochondrial bioenergetics and limb dysfunction in a novel murine iliac arteriovenous fistula model.
JVS-vascular science. 3:345-362 [DOI] 10.1016/j.jvssci.2022.10.001. [PMID] 36439698.
2022
Interventional- and amputation-stage muscle proteomes in the chronically threatened ischemic limb.
Clinical and translational medicine. 12(1) [DOI] 10.1002/ctm2.658. [PMID] 35073463.
2022
Medical Image-Based Computational Fluid Dynamics and Fluid-Structure Interaction Analysis in Vascular Diseases.
Frontiers in bioengineering and biotechnology. 10 [DOI] 10.3389/fbioe.2022.855791. [PMID] 35573253.
2022
Metabolomic profiling reveals muscle metabolic changes following iliac arteriovenous fistula creation in mice.
American journal of physiology. Renal physiology. 323(5):F577-F589 [DOI] 10.1152/ajprenal.00156.2022. [PMID] 36007889.
2022
Multiscale agent-based modeling of restenosis after percutaneous transluminal angioplasty: Effects of tissue damage and hemodynamics on cellular activity
Computers in Biology and Medicine. 147 [DOI] 10.1016/j.compbiomed.2022.105753.
2022
Phenotype clustering in health care: A narrative review for clinicians.
Frontiers in artificial intelligence. 5 [DOI] 10.3389/frai.2022.842306. [PMID] 36034597.
2022
S100A8 and S100A9 are elevated in chronically threatened ischemic limb muscle and induce ischemic mitochondrial pathology in mice.
JVS-vascular science. 3:232-245 [DOI] 10.1016/j.jvssci.2022.03.003. [PMID] 35647565.
2022
Superficial femoral artery stenting: Impact of stent design and overlapping on the local hemodynamics
Computers in Biology and Medicine. 143 [DOI] 10.1016/j.compbiomed.2022.105248.
2022
Temporal Dynamics of the Intestinal Microbiome Following Short-Term Dietary Restriction.
Nutrients. 14(14) [DOI] 10.3390/nu14142785. [PMID] 35889742.
2021
3D modelling of drug-coated balloons for the treatment of calcified superficial femoral arteries.
PloS one. 16(10) [DOI] 10.1371/journal.pone.0256783. [PMID] 34634057.
2021
Analyses of hemodialysis arteriovenous fistula geometric configuration and its associations with maturation and reintervention.
Journal of vascular surgery. 73(5):1778-1786.e1 [DOI] 10.1016/j.jvs.2020.09.033. [PMID] 33091518.
2021
Arteriovenous Fistula Maturation, Functional Patency, and Intervention Rates.
JAMA surgery. 156(12):1111-1118 [DOI] 10.1001/jamasurg.2021.4527. [PMID] 34550312.
2021
Association between surgeon case volume and years of practice experience with open abdominal aortic aneurysm repair outcomes.
Journal of vascular surgery. 73(4):1213-1226.e2 [DOI] 10.1016/j.jvs.2020.07.065. [PMID] 32707388.
2021
Baseline local hemodynamics as predictor of lumen remodeling at 1-year follow-up in stented superficial femoral arteries.
Scientific reports. 11(1) [DOI] 10.1038/s41598-020-80681-8. [PMID] 33452294.
2021
Carotid Stent Explant Indications and Outcomes.
Annals of vascular surgery. 77:1-6 [DOI] 10.1016/j.avsg.2021.05.023. [PMID] 34411671.
2021
Contemporary management and outcomes of complex vascular surgical groin wound infections.
Journal of vascular surgery. 73(3):1031-1040.e4 [DOI] 10.1016/j.jvs.2020.06.119. [PMID] 32707390.
2021
Development of a murine iliac arteriovenous fistula model for examination of hemodialysis access-related limb pathophysiology.
JVS-vascular science. 2:247-259 [DOI] 10.1016/j.jvssci.2021.09.022. [PMID] 34816137.
2021
Effect of ischemia-reperfusion on outcomes after open mesenteric bypass for chronic mesenteric ischemia.
Journal of vascular surgery. 74(4):1301-1308.e1 [DOI] 10.1016/j.jvs.2021.03.039. [PMID] 33887424.
2021
In-Stent Restenosis Progression in Human Superficial Femoral Arteries: Dynamics of Lumen Remodeling and Impact of Local Hemodynamics.
Annals of biomedical engineering. 49(9):2349-2364 [DOI] 10.1007/s10439-021-02776-1. [PMID] 33928465.
2021
Surgeon experience versus volume differentially affects lower extremity bypass outcomes in contemporary practice.
Journal of vascular surgery. 74(6):1978-1986.e2 [DOI] 10.1016/j.jvs.2021.05.029. [PMID] 34082002.
2021
Unique Metabolomic Profile of Skeletal Muscle in Chronic Limb Threatening Ischemia.
Journal of clinical medicine. 10(3) [DOI] 10.3390/jcm10030548. [PMID] 33540726.
2020
Computing patient-specific hemodynamics in stented femoral artery models obtained from computed tomography using a validated 3D reconstruction method.
Medical engineering & physics. 75:23-35 [DOI] 10.1016/j.medengphy.2019.10.005. [PMID] 31679904.
2020
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.
Circulation. 142(17):1633-1646 [DOI] 10.1161/CIRCULATIONAHA.120.047544. [PMID] 32981348.
2020
Haemodynamics of Different Configurations of a Left Subclavian Artery Stent Graft for Thoracic Endovascular Aortic Repair.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 59(1):7-15 [DOI] 10.1016/j.ejvs.2019.06.028. [PMID] 31761570.
2020
Heterogeneous and dynamic lumen remodeling of the entire infrainguinal vein bypass grafts in patients.
Journal of vascular surgery. 71(5):1620-1628.e3 [DOI] 10.1016/j.jvs.2019.05.069. [PMID] 31611109.
2020
Temporal analysis of arch artery diameter and flow rate in patients undergoing aortic arch endograft procedures.
Physiological measurement. 41(3) [DOI] 10.1088/1361-6579/ab7b40. [PMID] 32109898.
2019
A unified mapping framework of multifaceted pharmacodynamic responses to hypertension interventions.
Drug discovery today. 24(3):883-889 [DOI] 10.1016/j.drudis.2019.01.009. [PMID] 30690194.
2019
A versatile hybrid agent-based, particle and partial differential equations method to analyze vascular adaptation.
Biomechanics and modeling in mechanobiology. 18(1):29-44 [DOI] 10.1007/s10237-018-1065-0. [PMID] 30094656.
2019
An omnidirectional visualization model of personalized gene regulatory networks
npj Systems Biology and Applications. 5(1) [DOI] 10.1038/s41540-019-0116-1. [PMID] 31632690.
2019
Anatomic and hemodynamic investigation of an occluded common carotid chimney stent graft for hybrid thoracic aortic aneurysm repair.
Journal of vascular surgery cases and innovative techniques. 5(2):187-194 [DOI] 10.1016/j.jvscit.2019.02.007. [PMID] 31193609.
2019
Chronic kidney disease exacerbates ischemic limb myopathy in mice via altered mitochondrial energetics
Scientific Reports. 9(1) [DOI] 10.1038/s41598-019-52107-7. [PMID] 31664123.
2019
Contemporary outcomes of thoracofemoral bypass.
Journal of vascular surgery. 69(4):1150-1159.e1 [DOI] 10.1016/j.jvs.2018.07.053. [PMID] 30292606.
2019
Cyclophilin A contributes to aortopathy induced by postnatal loss of smooth muscle TGFBR1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(10):11396-11410 [DOI] 10.1096/fj.201900601RR. [PMID] 31311317.
2019
Expression of a Functional IL-2 Receptor in Vascular Smooth Muscle Cells
The Journal of Immunology. 202(3):694-703 [DOI] 10.4049/jimmunol.1701151.
2019
Financial implications of coding inaccuracies in patients undergoing elective endovascular abdominal aortic aneurysm repair.
Journal of vascular surgery. 69(1):210-218 [DOI] 10.1016/j.jvs.2018.04.027. [PMID] 29937283.
2019
Impact of secondary interventions on mortality after fenestrated branched endovascular aortic aneurysm repair.
Journal of vascular surgery. 70(6):1737-1746.e1 [DOI] 10.1016/j.jvs.2019.02.029. [PMID] 31420254.
2019
Implications of secondary aortic intervention after thoracic endovascular aortic repair for acute and chronic type B dissection.
Journal of vascular surgery. 69(5):1367-1378 [DOI] 10.1016/j.jvs.2018.07.080. [PMID] 30553732.
2019
Interaction between frailty and sex on mortality after elective abdominal aortic aneurysm repair.
Journal of vascular surgery. 70(6):1831-1843 [DOI] 10.1016/j.jvs.2019.01.086. [PMID] 31147120.
2019
Management of patch infections after carotid endarterectomy and utility of femoral vein interposition bypass graft.
Journal of vascular surgery. 69(6):1815-1823.e1 [DOI] 10.1016/j.jvs.2018.09.036. [PMID] 30591294.
2019
Novel Use of the PECS II Block in Major Vascular Surgery: A Case Report.
A&A practice. 13(4):145-147 [DOI] 10.1213/XAA.0000000000001019. [PMID] 30985315.
2019
Outcomes of antegrade and retrograde open mesenteric bypass for acute mesenteric ischemia.
Journal of vascular surgery. 69(1):129-140 [DOI] 10.1016/j.jvs.2018.04.063. [PMID] 30580778.
2018
A Computational Model-Based Framework to Plan Clinical Experiments – an Application to Vascular Adaptation Biology.
Computational Science–ICCS … : international conference … : proceedings. ICCS. 10860:352-362 [DOI] 10.1007/978-3-319-93698-7_27. [PMID] 31032487.
2018
A Twofold Usage of an Agent-Based Model of Vascular Adaptation to Design Clinical Experiments.
Journal of computational science. 29:59-69 [DOI] 10.1016/j.jocs.2018.09.013. [PMID] 30931048.
2018
Comparison of hemodialysis arteriovenous fistula blood flow rates measured by Doppler ultrasound and phase-contrast magnetic resonance imaging.
Journal of vascular surgery. 68(6):1848-1857.e2 [DOI] 10.1016/j.jvs.2018.02.043. [PMID] 29779960.
2018
Hyperacute Monocyte Gene Response Patterns Are Associated With Lower Extremity Vein Bypass Graft Failure.
Circulation. Genomic and precision medicine. 11(3) [DOI] 10.1161/CIRCGEN.117.001970. [PMID] 29530886.
2018
Implementation of a bundled protocol significantly reduces risk of spinal cord ischemia after branched or fenestrated endovascular aortic repair.
Journal of vascular surgery. 67(2):409-423.e4 [DOI] 10.1016/j.jvs.2017.05.136. [PMID] 29017806.
2018
Local Adipose-Associated Mediators and Adaptations Following Arteriovenous Fistula Creation.
Kidney international reports. 3(4):970-978 [DOI] 10.1016/j.ekir.2018.02.008. [PMID] 29988980.
2018
Outcomes of thoracic endovascular aortic repair in adult coarctation patients.
Journal of vascular surgery. 67(2):369-381.e2 [DOI] 10.1016/j.jvs.2017.06.103. [PMID] 28947226.
2017
Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).
Circulation. 135(15):1417-1428 [DOI] 10.1161/CIRCULATIONAHA.116.025707. [PMID] 28209728.
2017
Hemodynamic and Anatomic Predictors of Renovisceral Stent-Graft Occlusion Following Chimney Endovascular Repair of Juxtarenal Aortic Aneurysms.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 24(6):880-888 [DOI] 10.1177/1526602817731096. [PMID] 28914135.
2017
Hemodynamic Influence on Smooth Muscle Cell Kinetics and Phenotype During Early Vein Graft Adaptation.
Annals of biomedical engineering. 45(3):644-655 [DOI] 10.1007/s10439-016-1725-0. [PMID] 27624660.
2017
Linking gene dynamics to vascular hyperplasia – Toward a predictive model of vein graft adaptation.
PloS one. 12(11) [DOI] 10.1371/journal.pone.0187606. [PMID] 29190638.
2017
Miniature Endoscope for Multimodal Imaging
ACS Photonics. 4(1):174-180 [DOI] 10.1021/acsphotonics.6b00852.
2017
Outcomes of thoracic endovascular aortic repair using aortic arch chimney stents in high-risk patients.
Journal of vascular surgery. 66(1):9-20.e3 [DOI] 10.1016/j.jvs.2016.11.063. [PMID] 28216358.
2017
Pilot assessment of a human extracellular matrix-based vascular graft in a rabbit model.
Journal of vascular surgery. 65(3):839-847.e1 [DOI] 10.1016/j.jvs.2016.02.046. [PMID] 27139784.
2017
The spectrum of hand dysfunction after hemodialysis fistula placement.
Kidney international reports. 2(3):332-341 [DOI] 10.1016/j.ekir.2016.11.006. [PMID] 28845469.
2017
Vascular Adaptation: Pattern Formation and Cross Validation between an Agent Based Model and a Dynamical System.
Journal of theoretical biology. 429:149-163 [DOI] 10.1016/j.jtbi.2017.06.013. [PMID] 28645858.
2016
Access-related hand ischemia and the Hemodialysis Fistula Maturation Study.
Journal of vascular surgery. 64(4):1050-1058.e1 [DOI] 10.1016/j.jvs.2016.03.449. [PMID] 27478007.
2016
Arteriovenous Fistula Development in the First 6 Weeks after Creation.
Radiology. 279(2):620-9 [DOI] 10.1148/radiol.2015150385. [PMID] 26694050.
2016
Defining risk and identifying predictors of mortality for open conversion after endovascular aortic aneurysm repair.
Journal of vascular surgery. 63(4):873-81.e1 [DOI] 10.1016/j.jvs.2015.09.058. [PMID] 26613868.
2016
Multi-scale Modeling of the Cardiovascular System: Disease Development, Progression, and Clinical Intervention.
Annals of biomedical engineering. 44(9):2642-60 [DOI] 10.1007/s10439-016-1628-0. [PMID] 27138523.
2016
Outcomes after endovascular aneurysm repair conversion and primary aortic repair for urgent and emergency indications in the Society for Vascular Surgery Vascular Quality Initiative.
Journal of vascular surgery. 64(2):338-347 [DOI] 10.1016/j.jvs.2016.02.028. [PMID] 27288102.
2016
Preexisting smooth muscle cells contribute to neointimal cell repopulation at an incidence varying widely among individual lesions.
Surgery. 159(2):602-12 [DOI] 10.1016/j.surg.2015.08.015. [PMID] 26387788.
2016
Smooth muscle cell-specific Tgfbr1 deficiency attenuates neointimal hyperplasia but promotes an undesired vascular phenotype for injured arteries.
Physiological reports. 4(23) [PMID] 27923978.
2016
Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events.
Scientific reports. 6 [DOI] 10.1038/srep35444. [PMID] 27739498.
2016
Systemic inflammation as a predictor of clinical outcomes after lower extremity angioplasty/stenting.
Journal of vascular surgery. 64(3):766-778.e5 [DOI] 10.1016/j.jvs.2015.04.399. [PMID] 26054584.
2015
A multiscale computational framework to understand vascular adaptation
Journal of Computational Science. 8:32-47 [DOI] 10.1016/j.jocs.2015.02.002. [PMID] 25977733.
2015
Connexin43 Inhibition Prevents Human Vein Grafts Intimal Hyperplasia.
PloS one. 10(9) [DOI] 10.1371/journal.pone.0138847. [PMID] 26398895.
2015
Hypertension overrides the protective effect of female hormones on the development of aortic aneurysm secondary to Alk5 deficiency via ERK activation.
American journal of physiology. Heart and circulatory physiology. 308(2):H115-25 [DOI] 10.1152/ajpheart.00521.2014. [PMID] 25398982.
2015
The correlation between computed tomography and duplex evaluation of autogenous vein bypass grafts and their relationship to failure.
Journal of vascular surgery. 62(6):1546-54.e1 [DOI] 10.1016/j.jvs.2015.06.220. [PMID] 26365660.
2015
Time and flow-dependent changes in the p27(kip1) gene network drive maladaptive vascular remodeling.
Journal of vascular surgery. 62(5):1296-302.e2 [DOI] 10.1016/j.jvs.2014.05.015. [PMID] 24953896.
2014
Critical analysis of results after chimney endovascular aortic aneurysm repair raises cause for concern.
Journal of vascular surgery. 60(4):865-73; discussion 873 [DOI] 10.1016/j.jvs.2014.03.295. [PMID] 24816514.
2014
Defining utility and predicting outcome of cadaveric lower extremity bypass grafts in patients with critical limb ischemia.
Journal of vascular surgery. 60(6):1554-64 [DOI] 10.1016/j.jvs.2014.06.009. [PMID] 25043889.
2014
Elective endovascular aortic repair conversion for type Ia endoleak is not associated with increased morbidity or mortality compared with primary juxtarenal aneurysm repair.
Journal of vascular surgery. 60(2):286-294.e1 [DOI] 10.1016/j.jvs.2014.02.046. [PMID] 24684769.
2014
Flow reversal promotes intimal thickening in vein grafts.
Journal of vascular surgery. 60(2):471-478.e1 [DOI] 10.1016/j.jvs.2013.06.081. [PMID] 24342069.
2014
Outcomes after redo aortobifemoral bypass for aortoiliac occlusive disease.
Journal of vascular surgery. 60(2):346-355.e1 [DOI] 10.1016/j.jvs.2014.02.002. [PMID] 24657290.
2013
A dynamical system that describes vein graft adaptation and failure.
Journal of theoretical biology. 336:209-20 [DOI] 10.1016/j.jtbi.2013.07.006. [PMID] 23871714.
2013
Functional Outcome and Mortality After Open and Endovascular Secondary Intervention for Thoracic Endovascular Aortic Repair
Journal of Vascular Surgery. 57:293-294
2013
Outcomes Following Open and Endovascular Revascularization for Chronic Mesenteric Ischemia
Journal of Vascular Surgery. 57
2013
Prediction of graft patency and mortality after distal revascularization and interval ligation for hemodialysis access-related hand ischemia.
Journal of vascular surgery. 57(2):451-8 [DOI] 10.1016/j.jvs.2012.08.105. [PMID] 23244784.
2013
Reconstructing regulatory networks from the dynamic plasticity of gene expression by mutual information.
Nucleic acids research. 41(8) [DOI] 10.1093/nar/gkt147. [PMID] 23470995.
2013
Rule-based model of vein graft remodeling.
PloS one. 8(3) [DOI] 10.1371/journal.pone.0057822. [PMID] 23533576.
2013
Serial analysis of lumen geometry and hemodynamics in human arteriovenous fistula for hemodialysis using magnetic resonance imaging and computational fluid dynamics.
Journal of biomechanics. 46(1):165-9 [DOI] 10.1016/j.jbiomech.2012.09.005. [PMID] 23122945.
2013
Subclavian revascularization in the age of thoracic endovascular aortic repair and comparison of outcomes in patients with occlusive disease.
Journal of vascular surgery. 58(4):901-9 [DOI] 10.1016/j.jvs.2013.04.005. [PMID] 23711694.
2012
Cellular therapy with Ixmyelocel-T to treat critical limb ischemia: the randomized, double-blind, placebo-controlled RESTORE-CLI trial.
Molecular therapy : the journal of the American Society of Gene Therapy. 20(6):1280-6 [DOI] 10.1038/mt.2012.52. [PMID] 22453769.
2012
How to cluster gene expression dynamics in response to environmental signals.
Briefings in bioinformatics. 13(2):162-74 [DOI] 10.1093/bib/bbr032. [PMID] 21746694.
2012
Monocyte chemoattractant protein-1/CCR2 axis promotes vein graft neointimal hyperplasia through its signaling in graft-extrinsic cell populations.
Arteriosclerosis, thrombosis, and vascular biology. 32(10):2418-26 [DOI] 10.1161/ATVBAHA.112.255786. [PMID] 22904274.
2012
The dynamics of vein graft remodeling induced by hemodynamic forces: a mathematical model.
Biomechanics and modeling in mechanobiology. 11(3-4):411-23 [DOI] 10.1007/s10237-011-0321-3. [PMID] 21691849.
2011
Elevated Pen-Operative C-Reactive Protein Impedes Late Vein Graft Remodeling
Journal of Vascular Surgery. 53
2011
Functional mapping of expression quantitative trait loci that regulate oscillatory gene expression.
Methods in molecular biology (Clifton, N.J.). 734:241-55 [DOI] 10.1007/978-1-61779-086-7_12. [PMID] 21468993.
2011
Interim analysis results from the RESTORE-CLI, a randomized, double-blind multicenter phase II trial comparing expanded autologous bone marrow-derived tissue repair cells and placebo in patients with critical limb ischemia.
Journal of vascular surgery. 54(4):1032-41 [DOI] 10.1016/j.jvs.2011.04.006. [PMID] 21684715.
2010
Functional clustering of periodic transcriptional profiles through ARMA(p,q).
PloS one. 5(4) [DOI] 10.1371/journal.pone.0009894. [PMID] 20419127.
2010
Patient-centric analysis of dialysis access outcomes.
The journal of vascular access. 11(1):31-7 [PMID] 20119923.
2009
Established neointimal hyperplasia in vein grafts expands via TGF-beta-mediated progressive fibrosis.
American journal of physiology. Heart and circulatory physiology. 297(4):H1200-7 [DOI] 10.1152/ajpheart.00268.2009. [PMID] 19617405.
2009
Hemodynamically driven vein graft remodeling: a systems biology approach.
Vascular. 17 Suppl 1(Suppl 1):S2-9 [PMID] 19426605.
2009
Interplay of CCR2 signaling and local shear force determines vein graft neointimal hyperplasia in vivo.
FEBS letters. 583(21):3536-40 [DOI] 10.1016/j.febslet.2009.10.015. [PMID] 19822149.
2009
Revision of vein bypass grafts: factors affecting durability of interventions.
Seminars in vascular surgery. 22(4):261-6 [DOI] 10.1053/j.semvascsurg.2009.10.009. [PMID] 20006807.
2009
Rule-Based Simulation of Multi-Cellular Biological Systems-A Review of Modeling Techniques.
Cellular and molecular bioengineering. 2(3):285-294 [PMID] 21369345.
2008
An experiment-based model of vein graft remodeling induced by shear stress.
Annals of biomedical engineering. 36(7):1083-91 [DOI] 10.1007/s10439-008-9495-y. [PMID] 18415018.
2008
Danger Signaling Dependent Mechanisms in Flow-Induced Arterial Remodeling
Arteriosclerosis Thrombosis and Vascular Biology. 28
2008
Functional outcome after redo below-knee amputation.
World journal of surgery. 32(8):1823-6 [DOI] 10.1007/s00268-008-9500-5. [PMID] 18311498.
2008
Impact of endograft design and product line on the device cost of endovascular aneurysm repair.
Journal of vascular surgery. 47(3):499-503 [DOI] 10.1016/j.jvs.2007.10.051. [PMID] 18295102.
2008
Myd88-Dependent Pathway Initiates Neointimal Hyperplasia Development Independently of Tlr4
Circulation. 118
2007
A model of vein graft intimal hyperplasia.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2007:5807-10 [PMID] 18003333.
2007
Development of a microarray chip for gene expression in rabbit ocular research.
Molecular vision. 13:164-73 [PMID] 17293780.
2007
Impact of an absorbent silver-eluting dressing system on lower extremity revascularization wound complications.
Annals of vascular surgery. 21(5):598-602 [PMID] 17521872.
2007
Perioperative differences between endovascular repair of thoracic and abdominal aortic diseases.
Journal of vascular surgery. 45(1):86-9 [PMID] 17210388.
2007
Surgical and endovascular revision of infrainguinal vein bypass grafts: analysis of midterm outcomes from the PREVENT III trial.
Journal of vascular surgery. 46(6):1173-1179 [PMID] 17950564.
2007
TGF-beta- and CTGF-mediated fibroblast recruitment influences early outward vein graft remodeling.
American journal of physiology. Heart and circulatory physiology. 293(1):H482-8 [PMID] 17369455.
2007
TNF-alpha and shear stress-induced large artery adaptations.
The Journal of surgical research. 141(2):299-305 [PMID] 17574273.
2007
Tumor necrosis factor-alpha and the early vein graft.
Journal of vascular surgery. 45(1):169-76 [PMID] 17210403.
2006
Bone morphogenetic protein 4: potential regulator of shear stress-induced graft neointimal atrophy.
Journal of vascular surgery. 43(1):150-8 [PMID] 16414402.
2006
Clinical outcomes after closed, staged, and open forefoot amputations.
Journal of vascular surgery. 44(2):347-351; discussion 352 [PMID] 16890866.
2006
Early differential MMP-2 and -9 dynamics during flow-induced arterial and vein graft adaptations.
The Journal of surgical research. 134(2):327-34 [PMID] 16488440.
2006
Outcome after hypogastric artery bypass and embolization during endovascular aneurysm repair.
Journal of vascular surgery. 44(6):1162-8; discussion 1168 [PMID] 17145415.
2006
Results of PREVENT III: a multicenter, randomized trial of edifoligide for the prevention of vein graft failure in lower extremity bypass surgery.
Journal of vascular surgery. 43(4):742-751; discussion 751 [PMID] 16616230.
2005
Hepatic and splenic artery aneurysms.
Seminars in vascular surgery. 18(4):196-201 [PMID] 16360576.
2004
A novel vein graft model: adaptation to differential flow environments.
American journal of physiology. Heart and circulatory physiology. 286(1):H240-5 [PMID] 14500133.
2004
Differential expression and activity of matrix metalloproteinases during flow-modulated vein graft remodeling.
Journal of vascular surgery. 39(5):1084-90 [PMID] 15111865.
2004
Impact of IL-1beta on flow-induced outward arterial remodeling.
Surgery. 136(2):478-82 [PMID] 15300218.
2004
Impact of shear stress on early vein graft remodeling: a biomechanical analysis.
Annals of biomedical engineering. 32(11):1484-93 [PMID] 15636109.
2004
Wall shear modulation of cytokines in early vein grafts.
Journal of vascular surgery. 40(2):345-50 [PMID] 15297832.
2003
Morbidity with retroperitoneal procedures during endovascular abdominal aortic aneurysm repair.
Journal of vascular surgery. 38(3):459-63; discussion 464 [PMID] 12947255.
2002
A technique for combined hypogastric artery bypass and endovascular repair of complex aortoiliac aneurysms.
Journal of vascular surgery. 35(6):1289-91 [PMID] 12042744.
2002
Durability of antegrade synthetic aortomesenteric bypass for chronic mesenteric ischemia.
Journal of vascular surgery. 35(6):1078-84 [PMID] 12042717.
2002
Eligibility rates of ruptured and symptomatic AAA for endovascular repair.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 9(4):436-42 [PMID] 12223003.
2002
Flow-induced neointimal regression in baboon polytetrafluoroethylene grafts is associated with decreased cell proliferation and increased apoptosis.
Journal of vascular surgery. 36(6):1248-55 [PMID] 12469058.
2002
Increased plasmin and serine proteinase activity during flow-induced intimal atrophy in baboon PTFE grafts.
Arteriosclerosis, thrombosis, and vascular biology. 22(3):400-4 [PMID] 11884281.
2002
Prospective validation of an algorithm to maximize native arteriovenous fistulae for chronic hemodialysis access.
Journal of vascular surgery. 36(3):452-9 [PMID] 12218966.
2000
Mechanisms of vascular atrophy and fibrous cap disruption.
Annals of the New York Academy of Sciences. 902:153-61; discussion 161 [PMID] 10865835.
1999
Efficacy of dorsal pedal artery bypass in limb salvage for ischemic heel ulcers.
Journal of vascular surgery. 30(3):499-508 [PMID] 10477643.
1999
Elevated maternal urine level of beta-core fragment of human chorionic gonadotropin versus serum triple test in the second-trimester detection of down syndrome.
American journal of obstetrics and gynecology. 181(4):929-33 [PMID] 10521756.
1998
Covalent linkage of recombinant hirudin to a novel ionic poly(carbonate) urethane polymer with protein binding sites: determination of surface antithrombin activity.
Artificial organs. 22(8):657-65 [PMID] 9702317.
1998
Evaluation of a novel hirudin-coated polyester graft to physiologic flow conditions: hirudin bioavailability and thrombin uptake.
Journal of vascular surgery. 27(6):1117-27 [PMID] 9652474.
1997
Covalent linkage of recombinant hirudin to poly(ethylene terephthalate) (Dacron): creation of a novel antithrombin surface.
Biomaterials. 18(10):755-65 [PMID] 9158859.
1993
Modulation of myofibroblast proliferation by vascular prosthesis biomechanics.
ASAIO journal (American Society for Artificial Internal Organs : 1992). 39(3):M496-500 [PMID] 8268586.
1992
Evaluation of endothelium-derived nitric oxide mediated vasodilation utilizing ex vivo perfusion of an intact vessel.
The Journal of surgical research. 52(5):416-21 [PMID] 1619907.
1992
Experimental determination of velocity profiles and wall shear rate along the rabbit aortoiliac bifurcation: relationship to vessel wall low-density lipoprotein (LDL) metabolism.
Journal of biomechanics. 25(9):985-93 [PMID] 1387646.
1992
Spatial and temporal changes in compliance following implantation of bioresorbable vascular grafts.
Journal of biomedical materials research. 26(11):1449-61 [PMID] 1447229.
1991
Examination of the roles of glycoprotein Ib and glycoprotein IIb/IIIa in platelet deposition on an artificial surface using clinical antiplatelet agents and monoclonal antibody blockade.
Blood. 78(3):673-80 [PMID] 1859882.
1991
Mechanisms of vein graft atherosclerosis: LDL metabolism and endothelial actin reorganization.
Journal of vascular surgery. 13(2):336-47 [PMID] 1990174.
1990
Biomechanics of the venous wall under simulated arterial conditions.
Journal of biomechanics. 23(10):985-9 [PMID] 2229096.
1990
Experimental determination and mathematical model of the transient incorporation of cholesterol in the arterial wall.
Bulletin of mathematical biology. 52(6):711-32 [PMID] 2279192.
1990
Hemodynamics and low density lipoprotein metabolism. Rates of low density lipoprotein incorporation and degradation along medial and lateral walls of the rabbit aorto-iliac bifurcation.
Arteriosclerosis (Dallas, Tex.). 10(5):686-94 [PMID] 2403296.
1989
Cryopreserved venous homografts as vascular conduits in canine carotid arteries.
Surgery. 106(4):652-8; discussion 658 [PMID] 2508251.
1989
Hemodynamics alter arterial low-density lipoprotein metabolism.
Journal of vascular surgery. 10(4):392-9 [PMID] 2795764.

Grants

Jan 2024 ACTIVE
Single Nuclei Multiomic Analysis to Assess the Impact of Surgical Revascularization on Chronic Limb Threatening Ischemia
Role: Other
Funding: AMER HEART ASSOCIATION
Apr 2023 ACTIVE
The impact of e-cigarette exposure on skeletal muscle function in peripheral arterial disease
Role: Co-Investigator
Funding: FL DEPT OF HLTH BIOMED RES PGM/J&E KING
Aug 2022 ACTIVE
Outcomes and perspectives on treatment for critical limb ischemia in patients with end-stage renal disease
Role: Other
Funding: NATL INST OF HLTH NHLBI
Jul 2022 ACTIVE
Interdisciplinary Training for Vascular Surgeon Scientists
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Mar 2022 – Jan 2024
IMPACT: Investigation of Monitoring Pressure to Augment Compression Therapy
Role: Other
Funding: AMERICAN VENOUS FORUM FOUNDATION
Dec 2020 – Nov 2022
Improve PAD PERformance with METformin. The PERMET Trial
Role: Principal Investigator
Funding: NORTHWESTERN UNIV via NATL INST OF HLTH NHLBI
Jul 2020 – Oct 2022
Axline Fund – Research Project
Role: Principal Investigator
Funding: UF FOUNDATION
Jul 2020 – Jun 2021
Abbott Fund Cardiovascular Fellowship Program 2020-21
Role: Principal Investigator
Funding: ABBOTT FUND
Jun 2020 – Dec 2022
Initial Analysis to Evaluate the Application of Alucent Technology to Human Vein
Role: Principal Investigator
Funding: ALUCENT BIOMEDICAL
Apr 2020 ACTIVE
Exosomes as Key Signaling Mediators of Lower Extremity Vein Graft Outcomes
Role: Principal Investigator
Funding: VASCULAR CURES via WILLIAM K. BOWES, JR. FOUNDATION
Jan 2020 – Nov 2020
NFFRE Joint Personnel Agreement – Berceli PERMET Study
Role: Principal Investigator
Funding: NORTH FL FOU FOR RES AND EDU via NATL INST OF HLTH
Jan 2020 – Nov 2020
NFFRE Joint Personnel Agreement – Lauren Harvey PERMET Study
Role: Other
Funding: NORTH FL FOU FOR RES AND EDU via NATL INST OF HLTH NHLBI
Sep 2019 ACTIVE
Translational and Computational Analysis of Dialysis Fistula Maturation Failure
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Jul 2019 – Jun 2020
Abbott Fund Cardiovascular Fellowship Program 2019-2020
Role: Principal Investigator
Funding: ABBOTT FUND
Feb 2019 – Jan 2024
Short-Term Training for Medical Students in Cardiovascular and Pulmonary Research
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Jul 2018 – Jun 2019
Abbott Fund Cardiovascular Fellowship Program 2018-2019
Role: Principal Investigator
Funding: ABBOTT FUND
Jul 2017 – Jun 2018
Abbott Fund Cardiovascular Fellowship Program 2017-2018
Role: Principal Investigator
Funding: ABBOTT FUND
Jul 2016 – Sep 2018
Southern Arizona VA Health Care Systems (SAVAHCS) VA IPA – Dr. He
Role: Principal Investigator
Funding: SOUTHERN ARIZONA VA HEALTH CARE SYSTEM
Apr 2016 – Sep 2016
NFFRE Services Agreement
Role: Principal Investigator
Funding: NORTH FL FOU FOR RES AND EDU
Jun 2015 – Oct 2021
REnal TrAIning & reteNtion (RETAIN) Program
Role: Other
Funding: NATL INST OF HLTH NIDDK
Apr 2015 – Mar 2016
Department of Veterans Affairs, Cincinnati OH VA-IPA : Yong He
Role: Principal Investigator
Funding: US DEPT OF VET AFF CINCINNATI MED CTR
Jan 2014 – Jul 2017
Understanding Peripheral Restenosis: Genomic and Proteomic Determinants of Vascular Intervention (PREDICT-PVI)
Role: Principal Investigator
Funding: VASCULAR CURES
Aug 2013 – Dec 2019
Constitutive and Agent-Based Multiscale Models to Improve Vein Graft Survival
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Apr 2013 – Aug 2019
NSF I/UCRC AGREEMENT MEMBERSHIPS
Role: Principal Investigator
Funding: MULTIPLE SPONSORS
Apr 2013 – Mar 2019
I/UCRC: Collaborative Research: Full Center Grant: I/UCRC for Cyber-Physical Systems for the Hospital Operating Room
Role: Principal Investigator
Funding: NATL SCIENCE FOU
Mar 2012 – Aug 2020
UFRCC for Cardiovascular Cell Therapy Research Network
Role: Project Manager
Funding: NATL INST OF HLTH NHLBI
Jul 2011 – Apr 2017
Hemodynamics and Vascular Wall Biology Determine Arteriovenous Fistula Maturation
Role: Principal Investigator
Funding: UNIV OF UTAH via NATL INST OF HLTH NIDDK

Education

Fellowship – Vascular Surgery
2000 · University of Washington
Residency – Surgery
1998 · Beth Israel Deaconess Medical Center
Research Fellow – Vascular Surgery Laboratory
1996 · New England Deaconess Hospital
Medical Degree
1992 · University of Pittsburg School of Medicine
Ph.D. – Chemical Engineering
1990 · University of Pittsburgh
B.S. – Chemical Engineering
1985 · Massachusetts Institute of Technology

Contact Details

Phones:
Business:
(352) 548-6441
Emails:
Addresses:
Business Mailing:
PO Box 100128
GAINESVILLE FL 32610
Business Street:
PO Box 100128
GAINESVILLE FL 32610