Ali Zarrinpar, MD, PhD
Professor
Department:
MD-SURGERY-GEN-TRANSPLANT
Business Phone:
(352) 265-0606
Business Email:
ali.zarrinpar@surgery.ufl.edu
About Ali Zarrinpar
As a professor in the University of Florida Division of Transplantation and Hepatobiliary Surgery, I treat patients with liver cancer, liver disease, liver injury, bile duct cancer and bile duct injuries, mostly with surgery or with liver transplantation. Deceased donor transplantation grants me the privilege of making the most of tragedy and wrestling meaning from so many unanswered questions. I see transplantation as a miracle, and it amazes me every time.
My focus as a physician and scientist is on providing individualized care for each one of my patients. Right now, we work on the application of technology we develop in our lab to practical surgical and medical questions. Essentially, our focus is on getting the right drug or care to the right patient in the right amounts at the right times.
Before joining the division of transplantation and hepatobiliary surgery, I graduated with a doctorate degree in biochemistry and a medical degree from the University of California, San Francisco. Thereafter, I completed a general surgery residency and a fellowship in multivisceral transplant and hepatobiliary surgery from the University of California, Los Angeles.
On top of providing care for my patients, I am a diplomate in general surgery through the American Board of Surgery and a fellow of the American Society of Transplantation, dedicated to advancing the field of transplantation and improving patient care. I am also certified in multivisceral transplantation through the American Society of Transplant Surgeons.
When not practicing, I enjoy chauffeuring my children to their activities.
Teaching Profile
Courses Taught
2020,2022-2024
BCH6208 Advanced Metabolism: Regulation of Key Reactions in Carbohydrate and Lipid Metabolism
2020
BCH6207 Advanced Metabolism: Role of Membranes in Signal Transduction and Metabolic Control
2020-2024
BCH6206 Advanced Metabolism
2020-2024
GMS6905 Independent Studies in Medical Sciences
2018
MDC7600 Surgery Clerkship
2021,2023-2024
BCH4905 Biochemistry Senior Research
Board Certifications
-
ABSAmerican Board of Surgery
Clinical Profile
Specialties
- Transplant Surgery
- Transplant Surgery
Areas of Interest
- Bile duct obstruction
- Bile duct stricture
- Cholangiocarcinoma
- Choledocholithiasis
- Chronic cholecystitis
- Gastrointestinal cancer
- Hepatic hemangioma
- Hepatic ischemia
- Hepatic vein obstruction (Budd-Chiari)
- Kidney Transplant
- Laparoscopic gallbladder removal
- Liver Transplant
- Liver biopsy
- Liver cancer – hepatocellular carcinoma
- Liver disease
- Liver metastases
- Open gallbladder removal
Research Profile
Please see: https://surgery.med.ufl.edu/research/hepatobiliary-and-transplantation-laboratory/
Open Researcher and Contributor ID (ORCID)
0000-0002-6812-1816
Areas of Interest
- Multivisceral Transplantation
Publications
2024
Benchmark Outcomes in Deceased Donor Kidney Transplantation: A Multicenter Analysis of 80 996 Transplants From 126 Centers.
Transplantation direct.
10(5)
[DOI] 10.1097/TXD.0000000000001618.
[PMID] 38606349.
2024
Mechanisms of drug resistance in HCC
Hepatology.
79(4):926-940
[DOI] 10.1097/hep.0000000000000237.
2024
Quantitative methods for optimizing patient outcomes in liver transplantation
Liver Transplantation.
30(3):311-320
[DOI] 10.1097/lvt.0000000000000325.
2024
Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy.
Hepatology communications.
8(2)
[DOI] 10.1097/HC9.0000000000000370.
[PMID] 38285890.
2024
Transplantation’s next frontier: The promise of deceased donor studies
Liver Transplantation.
[DOI] 10.1097/lvt.0000000000000338.
2024
What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2023? Report of the Basic and Translational Research Committee of the International Liver Transplantation Society.
Transplantation.
[DOI] 10.1097/TP.0000000000004980.
[PMID] 38494468.
2023
American Society of Transplant Surgeons recommendations on best practices in donation after circulatory death organ procurement.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
23(2):171-179
[DOI] 10.1016/j.ajt.2022.10.009.
[PMID] 36695685.
2023
CCN2/CTGF promotes liver fibrosis through crosstalk with the Slit2/Robo signaling.
Journal of cell communication and signaling.
17(1):137-150
[DOI] 10.1007/s12079-022-00713-y.
[PMID] 36469291.
2023
Current Trends in Surgical Management of Hepatocellular Carcinoma.
Cancers.
15(22)
[DOI] 10.3390/cancers15225378.
[PMID] 38001637.
2023
Effects of Clinical and Tumor Characteristics on Survival in Patients with Hepatocellular Carcinoma with Bone Metastasis.
Journal of hepatocellular carcinoma.
10:1129-1141
[DOI] 10.2147/JHC.S417273.
[PMID] 37489126.
2023
Loss of CEACAM1 in endothelial cells causes hepatic fibrosis.
Metabolism: clinical and experimental.
144
[DOI] 10.1016/j.metabol.2023.155562.
[PMID] 37088122.
2023
Low vs Standard-Dose Indocyanine Green in the Identification of Biliary Anatomy Using Near-Infrared Fluorescence Imaging: A Multicenter Randomized Controlled Trial.
Journal of the American College of Surgeons.
236(4):711-717
[DOI] 10.1097/XCS.0000000000000553.
[PMID] 36728303.
2023
Personalized Tacrolimus Dosing After Liver Transplantation: A Randomized Clinical Trial.
medRxiv : the preprint server for health sciences.
[DOI] 10.1101/2023.05.26.23290604.
[PMID] 37397983.
2023
Physician-scientist trainees with parenting responsibilities need financial and childcare support.
Nature medicine.
29(12):2990-2992
[DOI] 10.1038/s41591-023-02606-y.
[PMID] 37853137.
2023
Portosystemic shunt placement reveals blood signatures for the development of hepatic encephalopathy through mass spectrometry.
Nature communications.
14(1)
[DOI] 10.1038/s41467-023-40741-9.
[PMID] 37652904.
2023
Pre- and Post-Portosystemic Shunt Placement Metabolomics Reveal Molecular Signatures for the Development of Hepatic Encephalopathy.
medRxiv : the preprint server for health sciences.
[DOI] 10.1101/2023.01.02.22281374.
[PMID] 36711444.
2023
Secondary Cold Ischemia After Normothermic Machine Perfusion: A Drawback to Centralized Organ Perfusion Centers?
Transplantation.
107(6):1237-1239
[DOI] 10.1097/TP.0000000000004569.
[PMID] 36922377.
2023
Sex differences in specialized pro-resolving lipid mediators and their receptors in abdominal aortic aneurysms.
JVS-vascular science.
4
[DOI] 10.1016/j.jvssci.2023.100107.
[PMID] 37292185.
2023
The Future Is Now: OrganEx Technology and Its Implications for Transplant Medicine.
Transplantation.
107(4):799-800
[DOI] 10.1097/TP.0000000000004496.
[PMID] 37001552.
2023
What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2022? Report of the Basic and Translational Research Committee of the International Liver Transplantation Society.
Transplantation.
107(4):808-814
[DOI] 10.1097/TP.0000000000004476.
[PMID] 36550624.
2022
Clinical Utility and Cost of Postoperative Hemoglobin Level Testing Following Robotic-assisted Hysterectomy for Endometrial Cancer.
Anticancer research.
42(4):1893-1898
[DOI] 10.21873/anticanres.15665.
[PMID] 35347007.
2022
High levels of donor-derived cell-free DNA in a case of graft-versus-host-disease following liver transplantation
American Journal of Transplantation.
22(3):973-976
[DOI] 10.1111/ajt.16894.
2022
Machine perfusion organ preservation: Highlights from the American Transplant Congress 2021.
Artificial organs.
46(2):315-320
[DOI] 10.1111/aor.14100.
[PMID] 34755348.
2022
New Approaches to the Diagnosis of Rejection and Prediction of Tolerance in Liver Transplantation.
Transplantation.
106(10):1952-1962
[DOI] 10.1097/TP.0000000000004160.
[PMID] 35594482.
2022
Resolution of inflammation via RvD1/FPR2 signaling mitigates Nox2 activation and ferroptosis of macrophages in experimental abdominal aortic aneurysms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
36(11)
[DOI] 10.1096/fj.202201114R.
[PMID] 36183323.
2022
What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2020-2021?-Report of the Basic and Translational Research Committee of the International Liver Transplantation Society.
Transplantation.
106(2):227-233
[DOI] 10.1097/TP.0000000000004003.
[PMID] 34856600.
2021
Do patients at high risk for Hepatitis C receive recommended testing? A retrospective cohort study of statewide Medicaid claims linked with OneFlorida clinical data.
Medicine.
100(50)
[DOI] 10.1097/MD.0000000000028316.
[PMID] 34918711.
2021
Inhibin-positive hepatic carcinoma: proposal for a solid-tubulocystic variant of intrahepatic cholangiocarcinoma
Human Pathology.
116:82-93
[DOI] 10.1016/j.humpath.2021.07.004.
2021
Machine Learning Applications in Solid Organ Transplantation and Related Complications.
Frontiers in immunology.
12
[DOI] 10.3389/fimmu.2021.739728.
[PMID] 34603324.
2021
Progress and challenges in diagnosis and treatment of rejection following liver transplantation.
Current opinion in organ transplantation.
26(6):669-674
[DOI] 10.1097/MOT.0000000000000924.
[PMID] 34581291.
2021
Racial Disparity in Liver Transplantation Listing.
Journal of the American College of Surgeons.
232(4):526-534
[DOI] 10.1016/j.jamcollsurg.2020.12.021.
[PMID] 33444709.
2021
Reassessment of the Hispanic Disparity: Hepatic Steatosis Is More Prevalent in Mexican Americans Than Other Hispanics
Hepatology Communications.
5(12):2068-2079
[DOI] 10.1002/hep4.1775.
[PMID] 34558824.
2021
Sex-Specific Differences in the Association Between Race/Ethnicity and NAFLD Among US Population.
Frontiers in medicine.
8
[DOI] 10.3389/fmed.2021.795421.
[PMID] 34926533.
2021
The Sobering Complexities of Alcoholic Liver Disease and Decisions for Transplant.
JAMA surgery.
156(11):1034-1035
[DOI] 10.1001/jamasurg.2021.3749.
[PMID] 34379089.
2020
Delayed Implantation of Pumped Kidneys Decreases Renal Allograft Futility in Combined Liver-Kidney Transplantation.
Transplantation.
104(8):1591-1603
[DOI] 10.1097/TP.0000000000003040.
[PMID] 32732836.
2020
Enabling Technologies for Personalized and Precision Medicine.
Trends in biotechnology.
38(5):497-518
[DOI] 10.1016/j.tibtech.2019.12.021.
[PMID] 31980301.
2020
Liver‐on‐a‐Chip Models of Fatty Liver Disease
Hepatology.
71(2):733-740
[DOI] 10.1002/hep.31106.
[PMID] 31909504.
2020
Phenotypic Response and Personalized Medicine in Liver Cancer and Transplantation: Approaches to Complex Systems
Advanced Therapeutics.
3(4)
[DOI] 10.1002/adtp.201900167.
2020
Prevalence and Predictors of Nonalcoholic Steatohepatitis Using Multiple Non-Invasive Methods: Data from NHANES III.
Journal of liver.
9(3)
[PMID] 37786752.
2020
Recent advances in precision medicine for individualized immunosuppression.
Current opinion in organ transplantation.
25(4):420-425
[DOI] 10.1097/MOT.0000000000000771.
[PMID] 32520785.
2020
What Can We Learn About Drug Safety and Other Effects in the Era of Electronic Health Records and Big Data That We Would Not Be Able to Learn From Classic Epidemiology?
Journal of Surgical Research.
246:599-604
[DOI] 10.1016/j.jss.2019.09.053.
[PMID] 31653413.
2019
A Targeted Swallow Screen for the Detection of Postoperative Dysphagia in Liver Transplant Patients.
Progress in transplantation (Aliso Viejo, Calif.).
29(1):4-10
[DOI] 10.1177/1526924818817035.
[PMID] 30514164.
2019
Factors predicting kidney delayed graft function among recipients of simultaneous liver‐kidney transplantation: A single‐center experience
Clinical Transplantation.
33(6)
[DOI] 10.1111/ctr.13569.
[PMID] 31006141.
2019
Metabolic factors affecting hepatocellular carcinoma in steatohepatitis
Liver International.
39(3):531-539
[DOI] 10.1111/liv.14002.
[PMID] 30427105.
2019
Quantitative Measure of Intestinal Permeability Using Blue Food Coloring
Journal of Surgical Research.
233:20-25
[DOI] 10.1016/j.jss.2018.07.005.
[PMID] 30502249.
2018
Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma.
Journal of Cancer.
9(1):1-12
[DOI] 10.7150/jca.21747.
[PMID] 29290764.
2018
Evaluation Of Early Allograft Function Using The Liver Graft Assessment Following Transplantation Risk Score Model.
Jama Surgery.
153(5):436-444
[DOI] 10.1001/jamasurg.2017.5040.
[PMID] 29261831.
2018
Heme Oxygenase-1 Regulates Sirtuin-1-Autophagy Pathway in Liver Transplantation: From Mouse to Human
American Journal of Transplantation.
18(5):1110-1121
[DOI] 10.1111/ajt.14586.
[PMID] 29136322.
2018
Hepatocyte transplantation: past efforts, current technology, and future expansion of therapeutic potential.
The Journal of surgical research.
226:48-55
[DOI] 10.1016/j.jss.2018.01.031.
[PMID] 29661288.
2018
Recombinant Relaxin Protects Liver Transplants From Ischemia Damage By Hepatocyte Glucocorticoid Receptor: From Bench-To-Bedside.
Hepatology.
68(1):258-273
[DOI] 10.1002/hep.29787.
[PMID] 29350771.
2017
Avoiding Futility in Simultaneous Liver-kidney Transplantation: Analysis of 331 Consecutive Patients Listed for Dual Organ Replacement.
Annals of surgery.
265(5):1016-1024
[DOI] 10.1097/SLA.0000000000001801.
[PMID] 27232249.
2017
Bruton Tyrosine Kinase Inhibition Attenuates Liver Damage in a Mouse Warm Ischemia and Reperfusion Model.
Transplantation.
101(2):322-331
[DOI] 10.1097/TP.0000000000001552.
[PMID] 27820779.
2017
Determination of hepatocellular carcinoma grade by needle biopsy is unreliable for liver transplant candidate selection.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
23(9):1123-1132
[DOI] 10.1002/lt.24811.
[PMID] 28688158.
2017
Evaluation of Patients With Hepatocellular Carcinomas That Do Not Produce α-Fetoprotein.
JAMA surgery.
152(1):55-64
[DOI] 10.1001/jamasurg.2016.3310.
[PMID] 27706479.
2017
Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury.
Journal of hepatology.
67(6):1232-1242
[DOI] 10.1016/j.jhep.2017.08.010.
[PMID] 28842295.
2017
Making N-of-1 Medicine a Reality.
SLAS technology.
22(3):231-232
[DOI] 10.1177/2472630317702449.
[PMID] 28520523.
2017
Metabolic Pathway Inhibition in Liver Cancer.
SLAS technology.
22(3):237-244
[DOI] 10.1177/2472630317698683.
[PMID] 28314110.
2017
Peritransplant pancreatitis: A marker of high mortality and graft failure in liver transplant patients.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
23(7):925-932
[DOI] 10.1002/lt.24760.
[PMID] 28294516.
2017
Safety and Efficacy of Electromagnetic-Guided Bedside Placement of Nasoenteral Feeding Tubes versus Standard Placement.
The American surgeon.
83(10):1184-1187
[PMID] 29391121.
2017
Sirtuin 1 attenuates inflammation and hepatocellular damage in liver transplant ischemia/Reperfusion: From mouse to human.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
23(10):1282-1293
[DOI] 10.1002/lt.24821.
[PMID] 28719070.
2017
The Therapeutic Potential of T Cell Metabolism.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
17(7):1705-1712
[DOI] 10.1111/ajt.14149.
[PMID] 27931083.
2016
Diamonds, Digital Health, and Drug Development: Optimizing Combinatorial Nanomedicine.
ACS nano.
10(10):9087-9092
[DOI] 10.1021/acsnano.6b06174.
[PMID] 27682869.
2016
Early cytokine signatures of ischemia/reperfusion injury in human orthotopic liver transplantation.
JCI insight.
1(20)
[DOI] 10.1172/jci.insight.89679.
[PMID] 27942590.
2016
Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform.
Science translational medicine.
8(333)
[DOI] 10.1126/scitranslmed.aac5954.
[PMID] 27053773.
2016
Intraoperative Laparoscopic Near-Infrared Fluorescence Cholangiography to Facilitate Anatomical Identification: When to Give Indocyanine Green and How Much.
Surgical innovation.
23(4):360-5
[DOI] 10.1177/1553350616637671.
[PMID] 26964557.
2016
Mind MELD or Ignore It at Your Peril.
JAMA surgery.
151(7)
[DOI] 10.1001/jamasurg.2016.0839.
[PMID] 27191733.
2016
Portable device for the analysis of liver function: a boon to liver surgery and critical care.
Expert review of medical devices.
13(1):1-4
[DOI] 10.1586/17434440.2016.1126178.
[PMID] 26613130.
2016
Quantification of hepatic functional capacity: a call for standardization.
Expert review of gastroenterology & hepatology.
10(1):9-11
[DOI] 10.1586/17474124.2016.1116938.
[PMID] 26561002.
2016
TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice.
Gastroenterology.
150(3):707-19
[DOI] 10.1053/j.gastro.2015.11.002.
[PMID] 26582088.
2015
A novel prognostic nomogram accurately predicts hepatocellular carcinoma recurrence after liver transplantation: analysis of 865 consecutive liver transplant recipients.
Journal of the American College of Surgeons.
220(4):416-27
[DOI] 10.1016/j.jamcollsurg.2014.12.025.
[PMID] 25690672.
2015
A rapid, reproducible, noninvasive predictor of liver graft survival.
The Journal of surgical research.
197(1):183-90
[DOI] 10.1016/j.jss.2015.03.093.
[PMID] 25940156.
2015
A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma.
Diseases (Basel, Switzerland).
3(4):221-252
[DOI] 10.3390/diseases3040221.
[PMID] 28943622.
2015
Acetaminophen hepatotoxicity: an updated review.
Archives of toxicology.
89(2):193-9
[DOI] 10.1007/s00204-014-1432-2.
[PMID] 25537186.
2015
Complete pathologic response to pretransplant locoregional therapy for hepatocellular carcinoma defines cancer cure after liver transplantation: analysis of 501 consecutively treated patients.
Annals of surgery.
262(3):536-45; discussion 543
[DOI] 10.1097/SLA.0000000000001384.
[PMID] 26258323.
2015
Damage Control as a Strategy to Manage Postreperfusion Hemodynamic Instability and Coagulopathy in Liver Transplant.
JAMA surgery.
150(11):1066-72
[DOI] 10.1001/jamasurg.2015.1853.
[PMID] 26308380.
2015
Liver transplantation: Evading antigens-ABO-incompatible liver transplantation.
Nature reviews. Gastroenterology & hepatology.
12(12):676-8
[DOI] 10.1038/nrgastro.2015.193.
[PMID] 26577350.
2015
RE: Anesthetic Management for Resection of Hepatic Paraganglioma Metastatic From the Donor Organ in an Orthotopic Liver Transplant Recipient: A Case Report.
Transplantation proceedings.
47(6):2072-3
[DOI] 10.1016/j.transproceed.2015.07.012.
[PMID] 26293099.
2014
Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections.
Experimental and molecular pathology.
97(3):399-410
[DOI] 10.1016/j.yexmp.2014.09.002.
[PMID] 25218810.
2014
Liver transplantation in recipients receiving renal replacement therapy: outcomes analysis and the role of intraoperative hemodialysis.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
14(7):1638-47
[DOI] 10.1111/ajt.12759.
[PMID] 24854341.
2014
Reoperative complications after primary orthotopic liver transplantation: a contemporary single-center experience in the post-model for end-stage liver disease era.
Journal of the American College of Surgeons.
219(5):993-1000
[DOI] 10.1016/j.jamcollsurg.2014.07.005.
[PMID] 25127506.
2013
Assessment of hepatic steatosis by transplant surgeon and expert pathologist: a prospective, double-blind evaluation of 201 donor livers.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
19(4):437-49
[DOI] 10.1002/lt.23615.
[PMID] 23408461.
2013
Liver transplantation for lethal genetic syndromes: a novel model of personalized genomic medicine.
Journal of the American College of Surgeons.
216(4):534-43; discussion 543
[DOI] 10.1016/j.jamcollsurg.2012.12.050.
[PMID] 23521929.
2013
Liver transplantation: past, present and future.
Nature reviews. Gastroenterology & hepatology.
10(7):434-40
[DOI] 10.1038/nrgastro.2013.88.
[PMID] 23752825.
2013
The evolution of liver transplantation during 3 decades: analysis of 5347 consecutive liver transplants at a single center.
Annals of surgery.
258(3):409-21
[DOI] 10.1097/SLA.0b013e3182a15db4.
[PMID] 24022434.
2012
Immunomodulating options for liver transplant patients.
Expert review of clinical immunology.
8(6):565-78; quiz 578
[PMID] 22992151.
2012
Liver transplantation for nonalcoholic steatohepatitis: the new epidemic.
Annals of surgery.
256(4):624-33
[DOI] 10.1097/SLA.0b013e31826b4b7e.
[PMID] 22964732.
2012
Pneumothorax ex-vacuo or “trapped lung” in the setting of hepatic hydrothorax.
BMC pulmonary medicine.
12
[DOI] 10.1186/1471-2466-12-78.
[PMID] 23244504.
2012
Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease.
Alimentary pharmacology & therapeutics.
36(10):909-21
[DOI] 10.1111/apt.12084.
[PMID] 23057494.
2012
What is the prognosis after retransplantation of the liver?
Advances in surgery.
46:87-100
[PMID] 22873034.
2011
Liver transplantation for hepatocellular carcinoma: an update.
Hepatobiliary & pancreatic diseases international : HBPD INT.
10(3):234-42
[PMID] 21669564.
2011
Liver transplantation: Toward a unified allocation system.
Nature reviews. Gastroenterology & hepatology.
8(10):542-3
[DOI] 10.1038/nrgastro.2011.163.
[PMID] 21970965.
2010
Functional cortical neoplasms.
Cancer treatment and research.
153:163-86
[DOI] 10.1007/978-1-4419-0857-5_10.
[PMID] 19957225.
2007
Liver transplantation for HELLP syndrome.
The American surgeon.
73(10):1013-6
[PMID] 17983071.
2006
Sharp recanalization of a short esophageal occluding stricture in a patient with epidermolysis bullosa.
Gastrointestinal endoscopy.
64(5):793-6
[PMID] 17055877.
2005
A guide to antibiotics for the interventional radiologist.
Seminars in interventional radiology.
22(2):69-79
[DOI] 10.1055/s-2005-871861.
[PMID] 21326676.
2004
Sho1 and Pbs2 act as coscaffolds linking components in the yeast high osmolarity MAP kinase pathway.
Molecular cell.
14(6):825-32
[PMID] 15200959.
2003
Optimization of specificity in a cellular protein interaction network by negative selection.
Nature.
426(6967):676-80
[PMID] 14668868.
2003
Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms.
Science (New York, N.Y.).
299(5609):1061-4
[PMID] 12511654.
2003
The structure and function of proline recognition domains.
Science's STKE : signal transduction knowledge environment.
2003(179)
[PMID] 12709533.
2000
Converging on proline: the mechanism of WW domain peptide recognition.
Nature structural biology.
7(8):611-3
[PMID] 10932238.
1999
NMR structure of the mature dimer initiation complex of HIV-1 genomic RNA.
FEBS letters.
458(3):387-92
[PMID] 10570946.
Grants
Dec 2023
ACTIVE
AD HOC Trial: Artificial Intelligence-Based Drug Dosing in Hepatocellular Carcinoma
Role: Principal Investigator
Funding: SUN PHARMA GLOBAL FZE
Jul 2023
ACTIVE
Identifying Clinical and Molecular Determinants of Health Disparities in Hepatitis C and Hepatitis-C Related Hepatocellular Carcinoma
Role: Principal Investigator
Funding: American Society of Transplant Surgeons
Jul 2023
ACTIVE
Improving the efficacy of human primary hepatocyte transplantation: Implementation of a novel 3D peptide hydrogel
Role: Principal Investigator
Funding: AMER SOC OF TRANSPLANT PHYS
Jul 2023
ACTIVE
Modeling the Molecular Pathways of the Hispanic NAFLD/NASH Disparity in Human Precision Cut Liver Slices.
Role: Principal Investigator
Funding: AMER SOC OF TRANSPLANT PHYS
May 2023
ACTIVE
Using Transcriptional Assessment of Immune Response to Assess Immunosuppression After Liver Transplantation
Role: Principal Investigator
Funding: TRANSPLANT GENOMICS
Apr 2023
– Mar 2024
A trial of transplanting Hepatitis C-viremic kidneys into Hepatitis C-negative kidney recipients (THINKER-NEXT)
Role: Principal Investigator
Funding: UNIV OF PENNSYLVANIA
via NATL INST OF HLTH
Apr 2023
– Mar 2024
A trial of transplanting Hepatitis C-viremic kidneys into Hepatitis C-negative kidney recipients (THINKER-NEXT)
Role: Principal Investigator
Funding: UNIV OF PENNSYLVANIA
via NATL INST OF HLTH NIDDK
Nov 2022
ACTIVE
Global Utilization And Registry Database for Improved preservAtion of doNor LIVERs (GUARDIAN-LIVER)
Role: Principal Investigator
Funding: PARAGONIX TECHNOLOGIES
Jul 2022
ACTIVE
CTOA
Role: Principal Investigator
Funding: UNIV OF FLORIDA
Jul 2022
ACTIVE
Circulating tumor DNA to measure tumor burden in hepatocellular carcinoma
Role: Principal Investigator
Funding: BILLIONTOONE
Jul 2022
ACTIVE
Directing Tryptophan Immunometabolism to Ameliorate Ischemia-Reperfusion Injury
Role: Co-Investigator
Funding: AMER SOC OF TRANSPLANT PHYS
Apr 2022
ACTIVE
Directing Tryptophan Immunometabolism to Ameliorate Liver Ischemic-Reperfusion Injury
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Feb 2022
– Jan 2024
Utilization of visual artificial intelligence to improve intraoperative identification of biliary anatomy.
Role: Other
Funding: SOCIETY OF UNIVERSITY SURGEONS
Feb 2022
– Jan 2023
Bacterial DNA as a Diagnostic Biomarker of Hepatocellular Carcinoma
Role: Principal Investigator
Funding: UNIV OF CALIFORNIA SAN DIEGO
via NATL INST OF HLTH NCI
Jan 2022
ACTIVE
Sample Collection for Prospera Enhancement by Detecting ddcfDNA Levels
Role: Principal Investigator
Funding: NATERA
Jan 2022
– Apr 2023
Use of dd-cfDNA in Multi-Organ Transplant Rejection Detection
Role: Principal Investigator
Funding: NATERA
Jan 2022
ACTIVE
An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients
Role: Principal Investigator
Funding: QUANTUM LEAP HEALTHCARE COLLABORATIVE
Dec 2021
ACTIVE
Using Phenotypic Precision Medicine to Individualize Immunosuppression Based on Quantifiable Markers of Immune Response and Allograft Injury
Role: Principal Investigator
Funding: CAREDX
Mar 2021
ACTIVE
Understanding the spatial gene and protein regulations in human NAFLD progression
Role: Principal Investigator
Funding: REGENERON PHARMACEUTICALS
Sep 2020
– Aug 2021
Utilization of Phenotypic Precision Medicine to Identify Optimal Drug Combinations for the Treatment of Hepatocellular Carcinoma
Role: Principal Investigator
Funding: NATL INST OF HLTH NCATS
Jul 2020
– Jun 2023
2020 ASTA-Natera Research Grant: Using Phenotypic Precision Medicine to Individualize Immunosuppression Based on Quantifiable Markers of Immune Response and Allograft Injury
Role: Principal Investigator
Funding: AMER SOC OF TRANSPLANT PHYS
Jul 2020
– Jun 2023
Innovative techniques for organ preservation, repair and reconditioning
Role: Principal Investigator
Funding: American Society of Transplant Surgeons
Jul 2020
– Jun 2021
Microbial DNA as Diagnostic Marker for Hepatocellular Carcinoma
Role: Principal Investigator
Funding: UNIV OF CALIFORNIA SAN DIEGO
via Prevent Cancer Foundation
Jun 2020
– Feb 2023
University of Florida/Natera Collaborative study in dd-cfDNA quantitation after liver transplantation
Role: Principal Investigator
Funding: NATERA
Apr 2020
ACTIVE
The PROspera Kidney Transplant ACTIVE Rejection Assessment registry (ProActive) study
Role: Principal Investigator
Funding: NATERA
Sep 2019
– Nov 2023
Diversity Supplement: Novel Pathways in the Pathogenesis and Pathophysiology of NAFLD in Hispanics
Role: Other
Funding: OHIO UNIV
via NATL INST OF HLTH NIMHD
Aug 2019
– May 2022
Duggan Fund – Research Project
Role: Principal Investigator
Funding: UF FOUNDATION
via DUGGAN LIVER CANCER AND TRANSPLANT FUND
Mar 2019
– Nov 2023
Novel pathways in the pathogenesis and pathophysiology of NAFLD in Hispanics
Role: Principal Investigator
Funding: OHIO UNIV
via NATL INST OF HLTH NIMHD
Sep 2018
– Aug 2021
Optimizing Immunosuppression Drug Dosing via Phenotypic Precision Medicine
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Sep 2017
– Aug 2020
Utilization of Phenotypic Precision Medicine to Identify Optimal Drug Combinations for the Treatment of Hepatocellular Carcinoma
Role: Principal Investigator
Funding: NATL INST OF HLTH NCATS
Sep 2017
– Jun 2023
Ischemia-reperfusion injury in liver transplantation
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Jul 2017
– Aug 2017
Quantitative Evaluation of Donor Liver Grafts
Role: Principal Investigator
Funding: ONELEGACY FOUNDATION
Jun 2017
– Jun 2019
2016 ASTS-Astellas Faculty Development Grant: Role of Neutrophil Activation in Ischemia Reperfusion Injury
Role: Principal Investigator
Funding: American Society of Transplant Surgeons
Education
Fellowship, Multivisceral transplant and hepatobiliary surgery
2010-2012
·
UCLA
Residency, General Surgery
2005-2010
·
UCLA
Medical School
2005
·
UCSF
Doctoral Degree, Biochemistry
2003
·
UCSF
Contact Details
Phones:
- Business:
- (352) 265-0606
Emails:
- Business:
- ali.zarrinpar@surgery.ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100118
1329 SW 16TH ST STE 2170.1
GAINESVILLE FL 32608 - Business Street:
-
PO Box 100118
1329 SW 16TH ST STE 2170.1
GAINESVILLE FL 32608