Mark S Bleiweis

Mark S Bleiweis, MD

William G. Lassiter Jr. And Aneice R. Lassiter Professor And Director, UF Health Congenital Heart Center

Department: MD-SURGERY-TCV-CARDIOVASC
Business Phone: (352) 273-5422
Business Email: bleiweis@ufl.edu

About Mark S Bleiweis

Mark S. Bleiweis, MD, is board-certified in surgery, thoracic and cardiac surgery and congenital heart surgery. He graduated with distinction from Cornell University with a bachelor’s degree in chemistry, and earned his medical degree from the University of California at San Diego. He served his general surgery residency at Harbor-UCLA Medical Center in Torrance, California; his thoracic surgery residency at the University of North Carolina at Chapel Hill; and his pediatric cardiothoracic surgery fellowship at the University of California San Francisco.

Since his arrival at the University of Florida in 2005, Dr. Bleiweis has been instrumental in expanding the center’s complement of pediatric cardiac specialists and making the UF Health Congenital Heart Center among the top centers in the country. Dr. Bleiweis’ cardiac team was the first in Florida to use the Berlin Heart® Ventricular Assist Device (a pediatric VAD), and the SynCardia® Total Artificial Heart. His team also was the first to use the SynCardia® Total Artificial Heart paired with the Freedom® portable driver for a pediatric patient.

Dr. Bleiweis has extensive experience in the pre- and postoperative management of newborns, including premature and low-birthweight babies. His expertise includes repairing complex, single-ventricle and valve defects, as well as treating patients who have underlying syndromes. 

Prior to his UF appointment, Dr. Bleiweis was medical director of Children’s Hospital of Orange County Heart Institute in Orange, California. He also served as medical director of the cardiothoracic intensive care unit at the University of North Carolina School of Medicine, Chapel Hill. 

In addition to his roles with the Congenital Heart Center, Dr. Bleiweis is a professor of surgery and pediatrics at UF, and serves as a mentor to students pursuing professions in the health care field. He is a widely sought speaker and was selected as the American Heart Association Heart Ball Honoree in February 2015. 

Dr. Bleiweis’ professional memberships include the Society of Thoracic Surgeons, American Association of Thoracic Surgery, Southern Thoracic Surgical Association, Congenital Heart Surgeons Society, and International Society of Heart and Lung Transplantation. He also is a founding member of the World Society for Pediatric and Congenital Heart Surgery.

Accomplishments

Member
2012-2018 · Adult Congenital Heart Association
Member
2010 · Society of Thoracic Surgeons
Member
2009-2018 · Congenital Heart Surgeons’ Society
Member
2009-2018 · Southern Thoracic Surgical Association
Member
2007 · World Society for Pediatric and Congenital Heart Surgery
Member
2005 · American Medical Association
Fellow
2004-2018 · American College of Surgery
STS verification
2004-2018 · The Society for Thoracic Surgeons
Member
2001-2018 · American Heart Association

Board Certifications

  • Thoracic Surgery
    American Board of Thoracic Surgery

Clinical Profile

Specialties
  • Thoracic and Cardiovascular Surgery
Subspecialties
  • Congenital Heart Surgery
Areas of Interest
  • Absent pulmonary valve
  • Anomalous left coronary artery from the pulmonary artery
  • Aortic arch syndrome
  • Aortic regurgitation
  • Aortic stenosis
  • Aortic valve surgery – open
  • Atrial fibrillation or flutter
  • Atrial septal defect (ASD)
  • Bicuspid aortic valve
  • Cardiomyopathy
  • Congenital heart defect – corrective surgery
  • Congenital heart disease
  • Double aortic arch
  • Double inlet left ventricle
  • Double outlet right ventricle
  • Down syndrome
  • Ebstein anomaly
  • Eisenmenger syndrome
  • Heart failure – overview
  • Heart transplant
  • Heart valve surgery
  • Hypertrophic cardiomyopathy
  • Hypoplastic left heart syndrome
  • Lung transplant
  • Marfan syndrome
  • Mitral regurgitation – acute
  • Mitral stenosis
  • Mitral valve surgery – open
  • Noonan syndrome
  • Patent ductus arteriosus
  • Patent foramen ovale
  • Pediatric Cardiology
  • Pediatric heart surgery
  • Pulmonary atresia
  • Pulmonary hypertension
  • Pulmonary valve stenosis
  • Tetralogy of Fallot
  • Total anomalous pulmonary venous return
  • Transposition of the great arteries
  • Tricuspid atresia
  • Tricuspid regurgitation
  • Truncus arteriosus
  • Turner syndrome
  • Ventricular septal defect

Publications

2021
A mini-thoracotomy approach for walking veno-arterial extracorporeal membranous oxygenation.
Journal of cardiac surgery. 36(4):1569-1571 [DOI] 10.1111/jocs.15232. [PMID] 33331047.
2021
Berlin Heart EXCOR and ACTION post-approval surveillance study report.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 40(4):251-259 [DOI] 10.1016/j.healun.2021.01.010. [PMID] 33579597.
2021
Quest for Biomarkers in Pediatric Cardiac Surgery.
The Annals of thoracic surgery. [DOI] 10.1016/j.athoracsur.2020.12.078. [PMID] 33607057.
2021
Risk factors associated with post-transplant superior caval vein stenosis in paediatric heart transplantation.
Cardiology in the young. 1-6 [DOI] 10.1017/S1047951121000573. [PMID] 33622444.
2020
Bivalirudin and Alteplase for Pulmonary Embolism Requiring Veno-Arterial Extracorporeal Membrane Oxygenation in an Adolescent.
The journal of extra-corporeal technology. 52(4):327-331 [DOI] 10.1182/ject-2000013. [PMID] 33343036.
2020
Bivalirudin May Reduce the Need for Red Blood Cell Transfusion in Pediatric Cardiac Patients on Extracorporeal Membrane Oxygenation.
ASAIO journal (American Society for Artificial Internal Organs : 1992). [DOI] 10.1097/MAT.0000000000001291. [PMID] 33031157.
2020
Coronary Arterial Abnormalities in Hypoplastic Left Heart Syndrome: Pathologic Characteristics of Archived Specimens.
Seminars in thoracic and cardiovascular surgery. 32(3):531-538 [DOI] 10.1053/j.semtcvs.2020.02.007. [PMID] 32060012.
2020
Isolated Right Superior Cava Drainage to the Left Atrium: An Uncommon Etiology of Cyanosis.
World journal for pediatric & congenital heart surgery. 11(4):528-530 [DOI] 10.1177/2150135120912401. [PMID] 32645773.
2020
Left Atrial Appendage Aneurysm Characterized by Multimodal Imaging.
World journal for pediatric & congenital heart surgery. 11(4):NP161-NP163 [DOI] 10.1177/2150135118769327. [PMID] 29888627.
2020
Pathologic Characteristics of 119 Archived Specimens Showing the Phenotypic Features of Hypoplastic Left Heart Syndrome.
Seminars in thoracic and cardiovascular surgery. 32(4):895-903 [DOI] 10.1053/j.semtcvs.2020.02.019. [PMID] 32092382.
2020
Postoperative vasoactive inotropic score is predictive of outcomes in pediatric heart transplantation.
Clinical transplantation. 34(8) [DOI] 10.1111/ctr.13986. [PMID] 32441792.
2020
Pulsatile ventricular assist device as a bridge to transplant for the early high-risk single-ventricle physiology.
The Journal of thoracic and cardiovascular surgery. [DOI] 10.1016/j.jtcvs.2020.09.071. [PMID] 33546851.
2020
Risk Factors for Seizures and Epilepsy in Children With Congenital Heart Disease.
Journal of child neurology. 35(7):442-447 [DOI] 10.1177/0883073820904912. [PMID] 32103693.
2020
Safety of a 2-Day Antibiotic Regimen After Delayed Chest Closure Post Pediatric Cardiac Surgery.
Journal of intensive care medicine. 35(8):805-809 [DOI] 10.1177/0885066618792849. [PMID] 30089431.
2019
A single centre experience with an evolving approach for the repair of coarctation of the aorta.
Cardiology in the young. 29(7):885-887 [DOI] 10.1017/S104795111900101X. [PMID] 31296278.
2019
Hybrid procedure with pulsatile ventricular assist device for hypoplastic left heart syndrome awaiting transplantation.
The Journal of thoracic and cardiovascular surgery. 158(2):e59-e61 [DOI] 10.1016/j.jtcvs.2018.12.025. [PMID] 30737110.
2019
Impact of 3D Printouts in Optimizing Surgical Results for Complex Congenital Heart Disease.
World journal for pediatric & congenital heart surgery. 10(5):533-538 [DOI] 10.1177/2150135119852316. [PMID] 31496399.
2019
Left Ventricular Aneurysm Following Blunt-Force Trauma in a Child.
CASE (Philadelphia, Pa.). 3(1):39-42 [DOI] 10.1016/j.case.2018.08.002. [PMID] 30828683.
2019
Outcomes of children supported with an intracorporeal continuous-flow left ventricular assist system.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 38(4):385-393 [DOI] 10.1016/j.healun.2018.09.015. [PMID] 30391197.
2019
Sub-acute neonatal hemochromatosis in an infant with hypoplastic left heart syndrome on ventricular assist device awaiting transplantation.
Pediatric transplantation. 23(7) [DOI] 10.1111/petr.13567. [PMID] 31407854.
2019
Thenar Muscle Oxygen Saturation Using Vascular Occlusion Test: A Novel Technique to Study Microcirculatory Abnormalities in Pediatric Heart Failure Patients.
Pediatric cardiology. 40(6):1151-1158 [DOI] 10.1007/s00246-019-02118-y. [PMID] 31098675.
2018
End-organ recovery post-ventricular assist device can prognosticate survival.
Journal of critical care. 44:57-62 [DOI] 10.1016/j.jcrc.2017.10.017. [PMID] 29065351.
2018
Heart Transplant in Patient With Isolated Left Superior Vena Cava by Atrial Appendage Rotation.
The Annals of thoracic surgery. 105(6):e279-e281 [DOI] 10.1016/j.athoracsur.2018.01.008. [PMID] 29410126.
2018
Heart Transplantation for Adult Congenital Heart Disease: Overview and Special Considerations
Cardiovascular Innovations and Applications. 3(1):73-84 [DOI] 10.15212/CVIA.2017.0043.
2018
Hypoplastic left heart in Turner’s syndrome: a primary indication for transplant?
Cardiology in the young. 28(3):458-460 [DOI] 10.1017/S1047951117001962. [PMID] 29233199.
2018
Managing extensive mitral valve and ventricular septal injuries secondary to penetrating trauma.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 53(1):284-285 [DOI] 10.1093/ejcts/ezx298. [PMID] 28958060.
2018
Recurrent nonbacterial thrombotic endocarditis: A novel therapeutic approach.
Journal of cardiology cases. 17(5):175-177 [DOI] 10.1016/j.jccase.2018.01.005. [PMID] 30279885.
2018
Single-stage repair of double outlet right ventricle with subpulmonic ventricular septal defect (Taussig-Bing anomaly).
Multimedia manual of cardiothoracic surgery : MMCTS. 2018 [DOI] 10.1510/mmcts.2018.005. [PMID] 29485771.
2017
Repair of truncus arteriosus with interrupted aortic arch (Van Praagh type A4).
Multimedia manual of cardiothoracic surgery : MMCTS. 2017 [DOI] 10.1510/mmcts.2017.020. [PMID] 29300077.
2017
Safe sternal reentry in all age groups with the Rultract Resternotomy Retractor™.
Journal of cardiac surgery. 32(10):639-641 [DOI] 10.1111/jocs.13204. [PMID] 28895190.
2016
Hybrid Stage 1 Palliation in a Patient With Hypoplastic Left Heart Syndrome and Unusual Decompressing Levoatrial Cardinal Vein in Turner Syndrome: Utility of Multimodality Imaging.
World journal for pediatric & congenital heart surgery. 7(3):375-6 [DOI] 10.1177/2150135116641908. [PMID] 27142408.
2016
Outcomes of pediatric patients supported with continuous-flow ventricular assist devices: A report from the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS).
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 35(5):585-90 [DOI] 10.1016/j.healun.2016.01.1228. [PMID] 27056612.
2015
Utilization and Outcomes of Continuous-Flow Ventricular Assist Devices in Pediatric: Patients: a Report From the Pediatric Interagency Registry for Mechanical Circulatory Support (Pedimacs)
Journal of Heart and Lung Transplantation. 34(4, S)
2014
The use of veno-venous extracorporeal membrane oxygenation for perinatal support of an infant with d-transposition of the great arteries, intact atrial and ventricular septa, and flow-restricted ductus arteriosus.
A & A case reports. 2(10):126-9 [DOI] 10.1213/XAA.0000000000000022. [PMID] 25611994.
2013
Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children.
Circulation. 127(16):1702-11 [DOI] 10.1161/CIRCULATIONAHA.112.000685. [PMID] 23538380.
2013
Cerebral and somatic oxygen saturations after repair of tetralogy of Fallot: effects of extubation on regional blood flow.
The Annals of thoracic surgery. 95(2):682-6 [DOI] 10.1016/j.athoracsur.2012.07.017. [PMID] 22959574.
2013
Inspiratory muscle strength training in infants with congenital heart disease and prolonged mechanical ventilation: a case report.
Physical therapy. 93(2):229-36 [DOI] 10.2522/ptj.20110348. [PMID] 22466028.
2013
Protocol for relative hydrodynamic assessment of tri-leaflet polymer valves.
Journal of visualized experiments : JoVE. (80) [DOI] 10.3791/50335. [PMID] 24193435.
2013
Surgical considerations in the management of hypoplastic left heart syndrome.
Seminars in cardiothoracic and vascular anesthesia. 17(2):128-36 [DOI] 10.1177/1089253213488947. [PMID] 23657434.
2011
Inspiratory muscle training in a child with nemaline myopathy and organ transplantation.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 12(2):e94-8 [DOI] 10.1097/PCC.0b013e3181dde680. [PMID] 20407395.
2009
Analysis of regional congenital cardiac surgical outcomes in Florida using the Society of Thoracic Surgeons Congenital Heart Surgery Database.
Cardiology in the young. 19(4):360-9 [DOI] 10.1017/S1047951109990151. [PMID] 19575843.
2009
Aortic aneurysms and dissection diagnosed by computed tomography 19 years after repair of coarctation.
Cardiology in the young. 19(4):398-9 [DOI] 10.1017/S1047951109990242. [PMID] 19476694.
2009
Evaluating the extracardiac Fontan conduit by multislice computed tomography: an emerging modality.
Cardiology in the young. 19(2):204-5 [DOI] 10.1017/S1047951109003783. [PMID] 19224676.
2009
Improved Brain Blood Flow During Acd-Cpr, Using a Novel Device for Active Chest Decompression in Swine Model of Cardiac Arrest
Circulation. 120
2009
Improved Hemodynamics During Cpr With the Use of a Novel Adhesive Glove Device for Active Compression Decompression With Itd in a Swine Model of Ischemic Cardiac Arrest
Critical Care Medicine. 37
2009
Improved Hemodynamics During Cpr With the Use of a Novel Adhesive Glove Device for Active Compression Decompression With Itd in a Swine Model of Ischemic Cardiac Arrest
Critical Care Medicine. 37
2009
The diagnostic process and perioperative and anesthetic management of an undiagnosed congenital cyanotic cardiac defect in an adult for trauma surgery.
Journal of clinical anesthesia. 21(6):454-8 [DOI] 10.1016/j.jclinane.2008.10.008. [PMID] 19833282.
2008
Ventricular assist device implantation in the pediatric population: does pump size selection and associated hemodynamics impact outcomes?
ASAIO journal (American Society for Artificial Internal Organs : 1992). 54(5):474-8 [DOI] 10.1097/MAT.0b013e3181888f2d. [PMID] 18812736.
2004
The effect of incorporating vessel compliance in a computational model of blood flow in a total cavopulmonary connection (TCPC) with caval centerline offset.
Journal of biomechanical engineering. 126(6):709-13 [PMID] 15796329.
View on: PubMed
2004
Trigger for intercellular adhesion molecule-1 expression in rat lungs transplanted from non-heart-beating donors.
The Annals of thoracic surgery. 77(3):1048-55; discussion 1055 [PMID] 14992925.
View on: PubMed
2002
Long term results of lung transplantation for cystic fibrosis.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 22(4):602-9 [PMID] 12297180.
View on: PubMed
2001
Maintenance of cAMP in non-heart-beating donor lungs reduces ischemia-reperfusion injury.
American journal of respiratory and critical care medicine. 163(7):1642-7 [PMID] 11401888.
View on: PubMed
2001
The Ross procedure in children and young adults: a word of caution.
The Journal of thoracic and cardiovascular surgery. 122(1):147-53 [PMID] 11436048.
View on: PubMed
1999
Reduced ischemia-reperfusion injury with rolipram in rat cadaver lung donors: effect of cyclic adenosine monophosphate.
The Annals of thoracic surgery. 67(1):194-9; discussion 199 [PMID] 10086548.
View on: PubMed
1996
Survival after trauma pneumonectomy: the pathophysiologic balance of shock resuscitation with right heart failure.
The American surgeon. 62(11):967-72 [PMID] 8895724.
View on: PubMed
1996
Tricuspid valve surgery: 15-year experience.
Journal of the National Medical Association. 88(10):645-8 [PMID] 8918069.
View on: PubMed
1994
Application of ultrafast computed tomography for diagnosis of perivalvular abscesses. Surgical implications.
Chest. 106(2):629-32 [PMID] 7774357.
View on: PubMed
1993
Ultrafast computed tomography in the diagnosis of diseases of great vessels.
American journal of cardiac imaging. 7(2):120-7 [PMID] 10148777.
View on: PubMed
1992
Conventional and ultrafast computed tomography in the detection of viable versus infarcted myocardium.
American journal of cardiac imaging. 6(3):228-36 [PMID] 10147622.
View on: PubMed

Grants

Jul 2018 ACTIVE
STeroids to REduce Systemic inflammation after neonatal heart Surgery (STRESS Trial) "Study"
Role: Principal Investigator
Funding: DUKE UNIV via NATL INST OF HLTH NCATS
Nov 2015 – Jul 2020
SYNCARDIA 50CC TEMPORARY TOTAL ARTIFICIAL HEART (TAH-T) ASA BRIDGE TO TRANSPLANT (BTT)
Role: Principal Investigator
Funding: SYNCARDIA SYSTEMS
Jul 2015 – Jun 2018
CMS Comprehensive Cardiac Care Program
Role: Principal Investigator
Funding: FL DEPT OF HLTH CHILDRENS MED SERVS
Oct 2013 – Oct 2016
SynCardia Freedom Driver System Study: Continued access policy (cap) phase
Role: Principal Investigator
Funding: SYNCARDIA SYSTEMS
Nov 2012 – Nov 2017
EXCOR Pediatric Ventricular Assist Device Post Approval Study
Role: Principal Investigator
Funding: BERLIN HEART INC

Education

Fellowship – Pediatric Cardiothoracic Surgery
1999-2000 · University of California
Residency – Thoracic Surgery
1996-1999 · University of North Carolina Chapel Hill
Residency – General Surgery
1989-1996 · Harbor – UCLA Medical Center
MD
1985-1989 · University of California San Diego
Bachelor of Science
1981-1985 · Cornell University

Teaching Profile

Courses Taught
2018
BME6010 Clinical Immersion

Contact Details

Phones:
Business:
(352) 273-5422
Emails:
Business:
bleiweis@ufl.edu