Karen S Thompson

Karen S Thompson,

UFHealth Physician

Business Phone: (352) 787-9838
Business Email: karenthompson@ufl.edu

About Karen S Thompson

Karen Thompson, DO, is a cardiovascular surgeon at UF Health Cardiothoracic Surgery in Leesburg.

Dr. Thompson earned her osteopathic medical degree from Midwestern University of Chicago and upon graduating was the recipient of the Dean’s Commendation Award. Following medical school, Thompson completed her Osteopathic internship at Illinois Masonic Medical Center.

Prior to joining UF Health, Dr. Thompson’s postdoctoral training included a 5-year general surgery residency at Jewish Hospital Kenwood in Cincinnati, Ohio. Following completion of her general surgery in 2004, Dr. Thompson completed her residency in Cardiothoracic Surgery in 2006 at the University Hospital of Mississippi. Dr Thompson continued to pursue a two-year adult cardiothoracic surgery fellowship at Emory University in Atlanta, finishing in 2008.

In addition to community clinical practice, Dr Thompson has spent time as a clinical faculty member at Northwestern University in Chicago, Illinois. There she received specialty training in mitral valve surgery working with one of the nationally known valve experts.

Dr. Thompson is board certified by the American Board of Thoracic Surgery. She holds memberships in the Society of Thoracic Surgeons, Southern Thoracic Surgical Association and the Florida Medical Association.


Chief Resident in Cardiothoracic Surgery
2005-2006 · University Hospital of Mississippi
Chief Resident in General Surgery
2003-2004 · Jewish Hospital Kenwood

Board Certifications

  • Thoracic Surgery
    American Board of Thoracic Surgery

Clinical Profile

  • Thoracic and Cardiovascular Surgery
  • Cardiovascular Disease
Areas of Interest
  • Aortic dissection
  • Aortic regurgitation
  • Aortic valve surgery – open
  • Cardiovascular
  • Congenital heart disease
  • Heart bypass surgery
  • Heart bypass surgery – minimally invasive
  • Heart disease
  • Transcatheter aortic valve replacement (TAVR)


Monochorionic Triplet Pregnancies With Twin Reversed Arterial Perfusion and Acardiac Triplet: Report of Two Cases and Literature Review.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 24(2):142-147 [DOI] 10.1177/1093526620984143. [PMID] 33439111.
A rapidly fatal case of anti-NMDA receptor encephalitis due to acute brain edema and herniation.
Neurology. 92(21):1014-1016 [DOI] 10.1212/WNL.0000000000007545. [PMID] 31019100.
Myocardial Infarction in the Neonate Without Coronary Artery Occlusion and Structurally Normal Heart: A Report of 2 Cases in Twin Pregnancies and Review of the Literature.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 22(6):571-578 [DOI] 10.1177/1093526619852219. [PMID] 31116662.
Paroxysmal Nocturnal Dyspnea Secondary to Right Ventricular Myxoma: A Novel Presentation of an Unusual Tumor.
Case reports in pediatrics. 2018 [DOI] 10.1155/2018/4791379. [PMID] 29682382.
Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy.
Scientific reports. 6 [DOI] 10.1038/srep31137. [PMID] 27511831.
Systemic and placental α-klotho: Effects of preeclampsia in the last trimester of gestation.
Placenta. 41:53-61 [DOI] 10.1016/j.placenta.2016.03.004. [PMID] 27208408.
Appendicitis as the presenting manifestation of Kawasaki disease.
Pediatric surgery international. 30(5):549-52 [DOI] 10.1007/s00383-013-3439-9. [PMID] 24317813.
Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus.
Journal of neuroinflammation. 11 [DOI] 10.1186/1742-2094-11-80. [PMID] 24750819.
Pericardial effusion and cardiac tamponade in neonates: sudden unexpected death associated with total parenteral nutrition via central venous catheterization.
Annals of clinical and laboratory science. 43(2):163-71 [PMID] 23694791.
View on: PubMed
Relaxin, its receptor (RXFP1), and insulin-like peptide 4 expression through gestation and in placenta accreta.
Reproductive sciences (Thousand Oaks, Calif.). 20(8):968-80 [DOI] 10.1177/1933719112472735. [PMID] 23302396.
Placental mesenchymal dysplasia.
American journal of obstetrics and gynecology. 205(6):e3-5 [DOI] 10.1016/j.ajog.2011.08.019. [PMID] 21974990.
Treatment of Gorham-Stout disease with zoledronic acid and interferon-α: a case report and literature review.
Journal of pediatric hematology/oncology. 32(8):579-84 [DOI] 10.1097/MPH.0b013e3181edb464. [PMID] 20962674.
Two cases of primary yolk sac tumor of the liver in childhood: case reports and literature review.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 12(5):410-6 [DOI] 10.2350/08-09-0521.1. [PMID] 19284801.
Placental mesenchymal dysplasia.
Archives of pathology & laboratory medicine. 131(1):131-7 [PMID] 17227114.
View on: PubMed


Fellowship in Cardiothoracic Surgery
2006-2008 · Emory University School of Medicine
Residency in Cardiothoracic Surgery
2004-2006 · University Hospital of Mississippi
Residency in General Surgery
1999-2003 · Jewish Hospital of Kenwood
Internship in Osteopathic (Rotating Internship)
1998-1999 · Illinois Masonic Medical Center
Internship in Surgery
1998-1999 · Advocate Illinois Masonic Medical Center
Medical Degree in Osteopathic Medicine
1994-1998 · Midwestern University of Chicago
Bachelor of Arts
1991-1994 · Saint Louis University
1986-1989 · Spokane Community College

Contact Details

(352) 787-9838