Lisa R Spiguel, MD
Associate Professor
Department:
MD-SURGERY-SURGONC-BMSE
Business Phone:
(352) 265-0535
Business Email:
lisa.spiguel@surgery.ufl.edu
About Lisa R Spiguel
Lisa R.P. Spiguel, M.D., is an associate professor with the University of Florida department of surgery in the division of general surgery’s surgical oncology service. She serves as the Section Chief of Breast surgery in the department of surgery, and clinical Director of the UF Health Breast Center.
Spiguel’s clinical focus is on the surgical care of breast cancer and benign breast disease, the assessment of high risk breast cancer patients and overall breast health. She offers the full spectrum of surgical breast care, including breast-conservation surgery, nipple- and skin-sparing mastectomies, modified radical mastectomies and axillary surgery. She uses an oncoplastic technique to rearrange breast tissue for a natural form after breast conservation surgery.
Prior to joining UF, she completed the Lynn Sage Breast Surgery Fellowship at Northwestern Memorial Hospital in Chicago. Prior to her fellowship, Spiguel trained in general surgery at the University of Chicago Medical Center and earned her medical degree at Wayne State University in Detroit.
Additional Positions:
Section Chief of Breast Surgery
2023 – Current
·
Department of Surgery
Clinical Director of the UF Health Breast Center
2012 – Current
·
University of Florida Cancer Center
Accomplishments
Academic Achievement Award
2011
·
University of Chicago, Department of Surgery
Administrative Chief Resident
2010-2011
·
University of Chicago, Department of Surgery
Academic Achievement Award
2010
·
University of Chicago, Department of Surgery
Teaching Profile
Courses Taught
2018
MDC7600 Surgery Clerkship
2018
MDC6001 Intro Clin Practice
2016-2018
MDT7600 Elect Top/Surgery
Board Certifications
-
SurgeryAmerican Board of Surgery
Clinical Profile
Specialties
- Cancer
- Surgical Oncology
Areas of Interest
- Breast Cancer
- Breast Cancer Surgery
- Breast Cancer in Men
- Breast Infection
- Breast Pain
- Intraoperative Radiation Therapy for Breast Cancer
- Preventive Health Care
Publications
Academic Articles
2025
Changes in Relationship Dynamics in Men and Women After Receiving the Diagnosis of Breast Versus Prostate Cancer: A Population-based Study.
Plastic and reconstructive surgery. Global open.
13(2)
[DOI] 10.1097/GOX.0000000000006494.
[PMID] 39989894.
2024
Postoperative Complications of Direct-to-Implant and Two-Staged Breast Reconstruction: A Stratified Analysis.
Plastic surgery (Oakville, Ont.).
[DOI] 10.1177/22925503241276541.
[PMID] 39553524.
2024
Surgical excision versus clinical follow-up: Outcomes of benign intraductal papillomas diagnosed on core needle biopsy.
American journal of surgery.
233:114-119
[DOI] 10.1016/j.amjsurg.2024.02.039.
[PMID] 38503684.
2024
Thrombotic Consequences of COVID-19 Infection on Microsurgical Reconstruction.
Microsurgery.
44(6)
[DOI] 10.1002/micr.31219.
[PMID] 39207212.
2023
Closed Incision Negative Pressure Therapy in Oncoplastic Surgery Prevents Delays to Adjuvant Therapy.
Plastic and reconstructive surgery. Global open.
11(5)
[DOI] 10.1097/GOX.0000000000005028.
[PMID] 37250834.
2023
Comparison of Aesthetic Outcomes of Epidermal Staples vs Sutures in Deep Epigastric Perforator Flap Breast Reconstruction.
Aesthetic surgery journal. Open forum.
5
[DOI] 10.1093/asjof/ojad098.
[PMID] 38075295.
2023
COVID-19 Associated Micro-Anastomotic Thrombosis After Abdominal Free Tissue Transfer: A Case Report and Literature Review.
Plastic surgery (Oakville, Ont.).
31(4):408-412
[DOI] 10.1177/22925503231161081.
[PMID] 37908324.
2023
Evaluation of an Artificial Intelligence System for Detection of Invasive Lobular Carcinoma on Digital Mammography.
Cureus.
15(5)
[DOI] 10.7759/cureus.38770.
[PMID] 37303390.
2023
Practical Approach to Establishing a Lymphedema Screening Program: Tips and Tricks.
Current Breast Cancer Reports.
2023
Proton Therapy for Bilateral Breast Cancer Maximizes Normal-Tissue Sparing.
International journal of particle therapy.
9(4):290-301
[DOI] 10.14338/IJPT-22-00041.1.
[PMID] 37169011.
2023
Salvage of Nipple-Areolar Complex Ischemia With Dimethyl Sulfoxide: A Case Series.
Annals of plastic surgery.
[DOI] 10.1097/SAP.0000000000003461.
[PMID] 36752563.
2023
The Novel Use of Magtrace in Chest Masculinizing Transgender Top Surgery.
Plastic and reconstructive surgery. Global open.
11(12)
[DOI] 10.1097/GOX.0000000000005466.
[PMID] 38093726.
2023
Young Adult Caregiving Daughters and Diagnosed Mothers Navigating Breast Cancer Together: Open and Avoidant Communication and Psychosocial Outcomes.
Cancers.
15(15)
[DOI] 10.3390/cancers15153864.
[PMID] 37568680.
2022
Hyperfractionated-Accelerated Reirradiation with Proton Therapy for Radiation-Associated Breast Angiosarcoma.
International journal of particle therapy.
8(4):55-67
[DOI] 10.14338/IJPT-21-00031.1.
[PMID] 35530187.
2021
Five-Year Breast Surgeon Experience in LYMPHA at Time of ALND for Treatment of Clinical T1-4N1-3M0 Breast Cancer.
Annals of surgical oncology.
28(10):5775-5787
[DOI] 10.1245/s10434-021-10551-8.
[PMID] 34365563.
2020
Concomitant Radiation Recall Dermatitis and Organizing Pneumonia following Breast Radiotherapy: A Case Report.
Case reports in oncology.
13(2):875-882
[DOI] 10.1159/000508493.
[PMID] 32884534.
2020
Retrospective analysis of surgically excised intraductal papillomas of the breast to further define management recommendations.
The breast journal.
26(5):1078-1080
[DOI] 10.1111/tbj.13656.
[PMID] 31628690.
2019
A Lymphedema Surveillance Program for Breast Cancer Patients Reveals the Promise of Surgical Prevention.
The Journal of surgical research.
244:604-611
[DOI] 10.1016/j.jss.2017.10.008.
[PMID] 29397949.
2019
Comment on A Letter to the Editor Regarding “Evaluation of Simplified Lymphatic Microsurgical Preventing Healing Approach (S-LYMPHA) for the Prevention of Breast Cancer-Related Clinical Lymphedema After Axillary Lymph Node Dissection”.
Annals of surgery.
270(2):e29-e30
[DOI] 10.1097/SLA.0000000000003037.
[PMID] 31305339.
2017
Fluorescein Isothiocyanate: A Novel Application for Lymphatic Surgery.
Annals of plastic surgery.
78(6S Suppl 5):S296-S298
[DOI] 10.1097/SAP.0000000000001034.
[PMID] 28328630.
2016
A Case of a Giant Borderline Phyllodes Tumor Early in Pregnancy Treated with Mastectomy and Immediate Breast Reconstruction.
The breast journal.
22(6):683-687
[DOI] 10.1111/tbj.12663.
[PMID] 27565020.
2016
Calciphylaxis of the Breast: A Case Report and Literature Review.
The breast journal.
22(5):568-72
[DOI] 10.1111/tbj.12632.
[PMID] 27332900.
2016
Ultrasound-Guided Segmental Mastectomy and Excisional Biopsy Using Hydrogel-Encapsulated Clip Localization as an Alternative to Wire Localization.
Annals of surgical oncology.
23(10):3284-9
[DOI] 10.1245/s10434-016-5325-x.
[PMID] 27338745.
2015
Improved Breast Cancer Care Quality Metrics After Implementation of a Standardized Tumor Board Documentation Template.
Journal of oncology practice.
11(5):421-3
[DOI] 10.1200/JOP.2015.003988.
[PMID] 26384016.
2015
Lymph node transplantation and quantitative clearance lymphoscintigraphy.
Plastic and reconstructive surgery.
135(5):937e-939e
[DOI] 10.1097/PRS.0000000000001203.
[PMID] 25700302.
2013
A Comparison of the Early Toxicities of Balloon Catheter High-Dose-Rate Brachytherapy (Bchdrb) and Intraoperative Radiation Therapy
International Journal of Radiation Oncology Biology Physics.
87
2013
Modulating vascular intimal hyperplasia using HSV-1 mutant requires activated MEK.
Gene therapy.
20(2):215-24
[DOI] 10.1038/gt.2012.26.
[PMID] 22418062.
2011
Hepatic metastasectomy for breast cancer and melanoma: trends in highly selected patients.
Oncology (Williston Park, N.Y.).
25(12):1173-5
[PMID] 22229209.
2011
Role of RANK-RANKL-OPG axis in cranial suture homeostasis.
The Journal of craniofacial surgery.
22(2):699-705
[DOI] 10.1097/SCS.0b013e3182077fbd.
[PMID] 21415639.
2011
Sentinel node biopsy alone for node-positive breast cancer: 12-year experience at a single institution.
Journal of the American College of Surgeons.
213(1):122-8; discussion 128
[DOI] 10.1016/j.jamcollsurg.2011.03.034.
[PMID] 21530326.
2010
Concomitant proliferation and caspase-3 mediated apoptosis in response to low shear stress and balloon injury.
The Journal of surgical research.
161(1):146-55
[DOI] 10.1016/j.jss.2008.11.001.
[PMID] 19482308.
2009
Nicotinic effects on vascular smooth muscle cell homeostasis.
The Journal of surgical research.
152(1):1-2
[DOI] 10.1016/j.jss.2008.01.022.
[PMID] 18468630.
2008
Commentary on “Embolic protection in infrainguinal interventions”.
Perspectives in vascular surgery and endovascular therapy.
20(1):68-9
[DOI] 10.1177/1531003508314706.
[PMID] 18388011.
2007
Metachronous giant brachial artery pseudoaneurysms: a case report and review of the literature.
Vascular and endovascular surgery.
41(5):467-72
[PMID] 17942866.
2006
Pediatric pelvic fractures: a marker for injury severity.
The American surgeon.
72(6):481-4
[PMID] 16808198.
Grants
Jan 2025
ACTIVE
A RANDOMIZED PHASE III TRIAL COMPARING AXILLARY LYMPH NODE DISSECTION TO AXILLARY RADIATION IN BREAST CANCER PATIENTS (cT1-3 N1) WHO HAVE POSITIVE SENTINEL LYMPH NODE DISEASE AFTER NEOADJUVANT CHEMOTHERAPY
Role: Principal Investigator
Funding: NRG ONCOLOGY FOU
via BREAST CANCER RESEARCH FOU
Sep 2023
ACTIVE
Assessing Benefits and Harms of Medical Cannabis and Cannabinoid Use in Breast Cancer Patients During and After Treatments
Role: Co-Investigator
Funding: UNIV OF MIAMI
via NATL INST OF HLTH NCI
Sep 2022
ACTIVE
UF HEALTH CANCER CENTER PILOT PROJECTS GRANTS FUNDED THROUGHTHE FLORIDA CONSORTIUM OF NATIONAL CANCER INSTITUTE CENTER
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL
Sep 2021
– Jan 2025
A RANDOMIZED PHASE III TRIAL COMPARING AXILLARY LYMPH NODE DISSECTION TO AXILLARY RADIATION IN BREAST CANCER PATIENTS (cT1-3 N1) WHO HAVE POSITIVE SENTINEL LYMPH NODE DISEASE AFTER NEOADJUVANT CHEMOTHERAPY
Role: Principal Investigator
Funding: NRG ONCOLOGY FOU
via BREAST CANCER RESEARCH FOU
Mar 2019
– Feb 2025
A RANDOMIZED PHASE III TRIAL COMPARING AXILLARY LYMPH NODE DISSECTION TO AXILLARY RADIATION IN BREAST CANCER PATIENTS (cT1-3 N1) WHO HAVE POSITIVE SENTINEL LYMPH NODE DISEASE AFTER NEOADJUVANT CHEMOTHERAPY
Role: Principal Investigator
Funding: NRG ONCOLOGY FOU
via NATL INST OF HLTH NCI
Mar 2019
– Feb 2025
A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer (E2108)
Role: Principal Investigator
Funding: EASTERN COOP ONCOLOGY GROUP
via NATL INST OF HLTH NCI
Mar 2019
– Feb 2025
ARM: Axillary reverse mappingA prospective trial to study rates of lymphedema and regional recurrence after sentinel lymph node biopsy and sentinel lymph node biopsy followed by axillary lymph node dissection with and without axillary reverse mapping
Role: Principal Investigator
Funding: NRG ONCOLOGY FOU
via NATL INST OF HLTH NCI
Jun 2013
– Sep 2019
A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer (E2108)
Role: Principal Investigator
Funding: EASTERN COOP ONCOLOGY GROUP
via NATL INST OF HLTH
Education
Lynn Sage Breast Surgery Fellowship
2012
·
Northwestern Memorial Hospital
Residency – Surgery
2011
·
University of Chicago
Medical Degree
2004
·
Wayne State University
Contact Details
Phones:
- Business:
- (352) 265-0535
Emails:
- Business:
- lisa.spiguel@surgery.ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100109
GAINESVILLE FL 32610