Kerri A O'Malley

Kerri A O'Malley, PhD

Assistant Professor

Department: MD-SURGERY-VASCULAR
Business Phone: (352) 273-5318
Business Email: komalley@ufl.edu

Teaching Profile

Courses Taught
2015
GMS6683 Fundamentals of Vascular Physiology and Pathology
2024
BMS6632 Endo and Reproduction
2024-2025
GMS7877 Responsible Conduct of Biomedical Research

Publications

Academic Articles
2024
Mitochondrial targeted catalase improves muscle strength following arteriovenous fistula creation in mice with chronic kidney disease.
Scientific reports. 14(1) [DOI] 10.1038/s41598-024-58805-1. [PMID] 38594299.
2024
Short-Term Dietary Restriction Potentiates an Anti-Inflammatory Circulating Mucosal-Associated Invariant T-Cell Response.
Nutrients. 16(8) [DOI] 10.3390/nu16081245. [PMID] 38674935.
2023
Activation of the Aryl Hydrocarbon Receptor in Muscle Exacerbates Ischemic Pathology in Chronic Kidney Disease.
Circulation research. 133(2):158-176 [DOI] 10.1161/CIRCRESAHA.123.322875. [PMID] 37325935.
2023
Chronic activation of the aryl hydrocarbon receptor in muscle exacerbates ischemic pathology in chronic kidney disease.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2023.05.16.541060. [PMID] 37292677.
2023
N-acetylcysteine treatment attenuates hemodialysis access-related limb pathophysiology in mice with chronic kidney disease.
American journal of physiology. Renal physiology. 325(3):F271-F282 [DOI] 10.1152/ajprenal.00083.2023. [PMID] 37439200.
2023
Single-Nuclei RNA-Sequencing of the Gastrocnemius Muscle in Peripheral Artery Disease.
Circulation research. 133(10):791-809 [DOI] 10.1161/CIRCRESAHA.123.323161. [PMID] 37823262.
2023
Temporal serum metabolomic and lipidomic analyses distinguish patients with access-related hand disability following arteriovenous fistula creation.
Scientific reports. 13(1) [DOI] 10.1038/s41598-023-43664-z. [PMID] 37798334.
2022
A Murine Model of Hemodialysis Access-related Hand Dysfunction.
Journal of visualized experiments : JoVE. (183) [DOI] 10.3791/63892. [PMID] 35723470.
2022
Influences of renal insufficiency and ischemia on mitochondrial bioenergetics and limb dysfunction in a novel murine iliac arteriovenous fistula model.
JVS-vascular science. 3:345-362 [DOI] 10.1016/j.jvssci.2022.10.001. [PMID] 36439698.
2022
Interventional- and amputation-stage muscle proteomes in the chronically threatened ischemic limb.
Clinical and translational medicine. 12(1) [DOI] 10.1002/ctm2.658. [PMID] 35073463.
2022
Metabolomic profiling reveals muscle metabolic changes following iliac arteriovenous fistula creation in mice.
American journal of physiology. Renal physiology. 323(5):F577-F589 [DOI] 10.1152/ajprenal.00156.2022. [PMID] 36007889.
2022
Temporal Dynamics of the Intestinal Microbiome Following Short-Term Dietary Restriction.
Nutrients. 14(14) [DOI] 10.3390/nu14142785. [PMID] 35889742.
2021
Development of a murine iliac arteriovenous fistula model for examination of hemodialysis access-related limb pathophysiology.
JVS-vascular science. 2:247-259 [DOI] 10.1016/j.jvssci.2021.09.022. [PMID] 34816137.
2021
Skeletal myopathy in CKD: a comparison of adenine-induced nephropathy and 5/6 nephrectomy models in mice.
American journal of physiology. Renal physiology. 321(1):F106-F119 [DOI] 10.1152/ajprenal.00117.2021. [PMID] 34121452.
2021
Unique Metabolomic Profile of Skeletal Muscle in Chronic Limb Threatening Ischemia.
Journal of clinical medicine. 10(3) [DOI] 10.3390/jcm10030548. [PMID] 33540726.
2019
Chronic kidney disease exacerbates ischemic limb myopathy in mice via altered mitochondrial energetics.
Scientific reports. 9(1) [DOI] 10.1038/s41598-019-52107-7. [PMID] 31664123.
2018
Hyperacute Monocyte Gene Response Patterns Are Associated With Lower Extremity Vein Bypass Graft Failure.
Circulation. Genomic and precision medicine. 11(3) [DOI] 10.1161/CIRCGEN.117.001970. [PMID] 29530886.
2017
Hemodynamic Influence on Smooth Muscle Cell Kinetics and Phenotype During Early Vein Graft Adaptation.
Annals of biomedical engineering. 45(3):644-655 [DOI] 10.1007/s10439-016-1725-0. [PMID] 27624660.
2017
Pilot assessment of a human extracellular matrix-based vascular graft in a rabbit model.
Journal of vascular surgery. 65(3):839-847.e1 [DOI] 10.1016/j.jvs.2016.02.046. [PMID] 27139784.
2016
Systemic inflammation as a predictor of clinical outcomes after lower extremity angioplasty/stenting.
Journal of vascular surgery. 64(3):766-778.e5 [DOI] 10.1016/j.jvs.2015.04.399. [PMID] 26054584.
2015
Time and flow-dependent changes in the p27(kip1) gene network drive maladaptive vascular remodeling.
Journal of vascular surgery. 62(5):1296-302.e2 [DOI] 10.1016/j.jvs.2014.05.015. [PMID] 24953896.
2014
Flow reversal promotes intimal thickening in vein grafts.
Journal of vascular surgery. 60(2):471-478.e1 [DOI] 10.1016/j.jvs.2013.06.081. [PMID] 24342069.
2011
Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage.
Laboratory investigation; a journal of technical methods and pathology. 91(12):1787-95 [DOI] 10.1038/labinvest.2011.94. [PMID] 21931299.
2011
Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling.
Journal of immunology (Baltimore, Md. : 1950). 187(2):911-8 [DOI] 10.4049/jimmunol.1100588. [PMID] 21690321.
2011
Sepsis induces early alterations in innate immunity that impact mortality to secondary infection.
Journal of immunology (Baltimore, Md. : 1950). 186(1):195-202 [DOI] 10.4049/jimmunol.1002104. [PMID] 21106855.
2008
Danger Signaling Dependent Mechanisms in Flow-Induced Arterial Remodeling
Arteriosclerosis Thrombosis and Vascular Biology. 28
2008
Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes.
Hepatology (Baltimore, Md.). 47(5):1725-36 [DOI] 10.1002/hep.22187. [PMID] 18311843.
2008
Myd88-Dependent Pathway Initiates Neointimal Hyperplasia Development Independently of Tlr4
Circulation. 118
2007
Genomic and proteomic determinants of lower extremity revascularization failure: rationale and study design.
Journal of vascular surgery. 45 Suppl A(Suppl A):A82-91 [PMID] 17544028.
2007
Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis.
Shock (Augusta, Ga.). 28(6):675-683 [PMID] 17621256.
2007
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis.
The Journal of experimental medicine. 204(6):1463-74 [PMID] 17548519.
2006
Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis.
Journal of immunology (Baltimore, Md. : 1950). 177(11):7943-9 [PMID] 17114466.
2006
Interleukin-6 and STAT3 protect the liver from hepatic ischemia and reperfusion injury during ischemic preconditioning.
Surgery. 140(5):793-802 [PMID] 17084723.
2006
Interleukin-6: Still crazy after all these years.
Critical care medicine. 34(10):2690-1 [PMID] 16983274.
2005
CD11c+ dendritic cells are required for survival in murine polymicrobial sepsis.
Journal of immunology (Baltimore, Md. : 1950). 175(5):3282-6 [PMID] 16116220.
2004
Stem cell fusion confusion.
Experimental hematology. 32(2):131-4 [PMID] 15102472.

Grants

Aug 2022 – Jul 2023
VA IPA for Kerri O'Malley
Role: Principal Investigator
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Sep 2018 – Aug 2019
VA IPA – CSP599 Kerri O'Malley
Role: Principal Investigator
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Aug 2013 – Dec 2019
Constitutive and Agent-Based Multiscale Models to Improve Vein Graft Survival
Role: Co-Investigator
Funding: NATL INST OF HLTH NHLBI

Contact Details

Phones:
Business:
(352) 273-5318
Emails:
Business:
komalley@ufl.edu
Addresses:
Business Mailing:
PO Box 100128
GAINESVILLE FL 32610
Business Street:
1601 SW ARCHER RD
Room E597
VA MEDICAL CENTER ROOM
GAINESVILLE FL 32608