Frederick A Moore

Frederick A Moore, MD, FACS, MCCM

Professor And Co-Director, Sepsis And Critical Illness Research Center

Department: MD-SURGERY-TRAUMA
Business Phone: (352) 273-5670

About Frederick A Moore

Dr. Frederick Moore is a professor. His clinical interests focus on acute care surgery, emergency surgery, surgical critical care, trauma surgery and sepsis. His research interests include translational efforts related to multiple organ failure, inflammatory response after trauma, and nutrition and the immune system.

Before joining UF in 2011, he led the division of surgical critical care and acute care surgery at The Methodist Hospital in Houston, and was a professor of surgery at Weill Cornell Medical College.

He completed his general surgery training at the University of Colorado Health Science Center in Denver and earned his medical degree from the University of Pittsburgh.

In 2011, the Society of Critical Care Medicine selected Moore as a Master Critical Care Medicine.

Board Certifications

  • Surgery
    American Board of Surgery
  • Surgical Critical Care
    American Board of Surgery

Clinical Profile

Specialties
  • Surgery
Subspecialties
  • Critical Care Surgery
Areas of Interest
  • Acute cholecystitis
  • Appendectomy
  • Appendicitis
  • Emergency airway puncture
  • Extracorporeal membrane oxygenation
  • Hernia
  • Laparoscopic gallbladder removal
  • Necrotizing soft tissue infection
  • Open gallbladder removal
  • Sepsis

Research Profile

Dr. Moore is the principal investigator for an NIH-funded P50 center grant for the UF Sepsis and Critical Illness Research Center to study the persistent inflammation, immunosuppression and catabolism syndrome (PICS) following sepsis in surgical intensive care unit patients.

Other research interests include:

Translational efforts related to multiple organ failure Inflammatory response after trauma Nutrition and the immune system

Publications

2021
Chronic Critical Illness and PICS Nutritional Strategies.
Journal of clinical medicine. 10(11) [DOI] 10.3390/jcm10112294. [PMID] 34070395.
2021
Chronic Critical Illness Elicits a Unique Circulating Leukocyte Transcriptome in Sepsis Survivors.
Journal of clinical medicine. 10(15) [DOI] 10.3390/jcm10153211. [PMID] 34361995.
2021
Clinical Impact of a Dedicated Trauma Hybrid Operating Room.
Journal of the American College of Surgeons. 232(4):560-570 [DOI] 10.1016/j.jamcollsurg.2020.11.008. [PMID] 33227422.
2021
Distinct immunologic endotypes are associated with clinical trajectory after severe blunt trauma and hemorrhagic shock.
The journal of trauma and acute care surgery. 90(2):257-267 [DOI] 10.1097/TA.0000000000003029. [PMID] 33214489.
2021
Enteral Nutrition Administration Record Prescribing Process Using Computerized Order Entry: A New Paradigm and Opportunities to Improve Outcomes in Critically Ill Patients.
JPEN. Journal of parenteral and enteral nutrition. 45(3):507-517 [DOI] 10.1002/jpen.1870. [PMID] 32384191.
2021
Identification of Unique microRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells after Hemorrhagic Shock and Polytrauma in Young and Old Adult Mice.
The journal of trauma and acute care surgery. [DOI] 10.1097/TA.0000000000003350. [PMID] 34252063.
2021
Lipid and lipoprotein predictors of functional outcomes and long-term mortality after surgical sepsis.
Annals of intensive care. 11(1) [DOI] 10.1186/s13613-021-00865-x. [PMID] 34018068.
2021
Nonocclusive mesenteric ischemia: A rare but lethal complication of enteral nutrition in critically ill patients.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. [DOI] 10.1002/ncp.10761. [PMID] 34462980.
2021
Older adults demonstrate biomarker evidence of the persistent inflammation, immunosuppression and catabolism syndrome (PICS) after sepsis.
The journals of gerontology. Series A, Biological sciences and medical sciences. [DOI] 10.1093/gerona/glab080. [PMID] 33721883.
2021
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.
Shock (Augusta, Ga.). 55(5):587-595 [DOI] 10.1097/SHK.0000000000001671. [PMID] 33021571.
2021
The Effect of Aging Physiology on Critical Care.
Critical care clinics. 37(1):135-150 [DOI] 10.1016/j.ccc.2020.08.006. [PMID] 33190766.
2021
The impact of sarcopenia and acute muscle mass loss on long-term outcomes in critically ill patients with intra-abdominal sepsis.
Journal of cachexia, sarcopenia and muscle. [DOI] 10.1002/jcsm.12752. [PMID] 34196134.
2021
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 35(2) [DOI] 10.1096/fj.202002150R. [PMID] 33140449.
2020
2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting.
World journal of emergency surgery : WJES. 15(1) [DOI] 10.1186/s13017-020-00313-4. [PMID] 32381121.
2020
Abdominal sepsis patients have a high incidence of chronic critical illness with dismal long-term outcomes.
American journal of surgery. 220(6):1467-1474 [DOI] 10.1016/j.amjsurg.2020.07.016. [PMID] 32807383.
2020
Clinical Trajectories of Acute Kidney Injury in Surgical Sepsis: A Prospective Observational Study.
Annals of surgery. [DOI] 10.1097/SLA.0000000000004360. [PMID] 33196489.
2020
Delayed interhospital transfer of critically ill patients with surgical sepsis.
The journal of trauma and acute care surgery. 88(1):169-175 [DOI] 10.1097/TA.0000000000002476. [PMID] 31856021.
2020
Development of a Simple Sequential Organ Failure Assessment Score for Risk Assessment of Emergency Department Patients With Sepsis.
Journal of intensive care medicine. 35(3):270-278 [DOI] 10.1177/0885066617741284. [PMID] 29141524.
2020
Immunological Endotyping of Chronic Critical Illness After Severe Sepsis.
Frontiers in medicine. 7 [DOI] 10.3389/fmed.2020.616694. [PMID] 33659259.
2020
Is there a role for tissue plasminogen activator as a novel treatment for refractory COVID-19 associated acute respiratory distress syndrome?
The journal of trauma and acute care surgery. 88(6):713-714 [DOI] 10.1097/TA.0000000000002694. [PMID] 32281766.
2020
Older Sepsis Survivors Suffer Persistent Disability Burden and Poor Long-Term Survival.
Journal of the American Geriatrics Society. 68(9):1962-1969 [DOI] 10.1111/jgs.16435. [PMID] 32294254.
2020
Persistently increased cell-free DNA concentrations only modestly contribute to outcome and host response in sepsis survivors with chronic critical illness.
Surgery. 167(3):646-652 [DOI] 10.1016/j.surg.2019.11.018. [PMID] 31898953.
2020
Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study.
Critical care (London, England). 24(1) [DOI] 10.1186/s13054-020-02917-3. [PMID] 32381107.
2020
Prospective Validation of a Transcriptomic Metric in Severe Trauma.
Annals of surgery. 271(5):802-810 [DOI] 10.1097/SLA.0000000000003204. [PMID] 30688688.
2020
Sequential Organ Failure Assessment Component Score Prediction of In-hospital Mortality From Sepsis.
Journal of intensive care medicine. 35(8):810-817 [DOI] 10.1177/0885066618795400. [PMID] 30165769.
2019
Cardiac pseudoaneurysm following non-operative management after penetrating thoracoabdominal trauma and pericardial window.
The journal of trauma and acute care surgery. 86(4):755-757 [DOI] 10.1097/TA.0000000000002189. [PMID] 30629012.
2019
Cell-free nuclear, but not mitochondrial, DNA concentrations correlate with the early host inflammatory response after severe trauma.
Scientific reports. 9(1) [DOI] 10.1038/s41598-019-50044-z. [PMID] 31541163.
2019
Current Epidemiology of Surgical Sepsis: Discordance Between Inpatient Mortality and 1-year Outcomes.
Annals of surgery. 270(3):502-510 [DOI] 10.1097/SLA.0000000000003458. [PMID] 31356275.
2019
LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P): Phase I/II clinical trial protocol of lipid emulsion therapy for stabilising cholesterol levels in sepsis and septic shock.
BMJ open. 9(9) [DOI] 10.1136/bmjopen-2019-029348. [PMID] 31537565.
2019
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis.
Critical care (London, England). 23(1) [DOI] 10.1186/s13054-019-2628-x. [PMID] 31722736.
2019
Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model.
Critical care medicine. 47(11):e919-e929 [DOI] 10.1097/CCM.0000000000003926. [PMID] 31389840.
2019
Persistent inflammation and anemia among critically ill septic patients.
The journal of trauma and acute care surgery. 86(2):260-267 [DOI] 10.1097/TA.0000000000002147. [PMID] 30489504.
2019
Persistently Elevated Glucagon-Like Peptide-1 Levels among Critically Ill Surgical Patients after Sepsis and Development of Chronic Critical Illness and Dismal Long-Term Outcomes.
Journal of the American College of Surgeons. 229(1):58-67.e1 [DOI] 10.1016/j.jamcollsurg.2019.04.014. [PMID] 30991107.
2019
Prognostic value of NT-proBNP levels in the acute phase of sepsis on lower long-term physical function and muscle strength in sepsis survivors.
Critical care (London, England). 23(1) [DOI] 10.1186/s13054-019-2505-7. [PMID] 31234943.
2019
The Development of Chronic Critical Illness Determines Physical Function, Quality of Life, and Long-Term Survival Among Early Survivors of Sepsis in Surgical ICUs.
Critical care medicine. 47(4):566-573 [DOI] 10.1097/CCM.0000000000003655. [PMID] 30664526.
2019
The evolving role of laparoscopic lavage and drainage.
The journal of trauma and acute care surgery. 86(2) [DOI] 10.1097/TA.0000000000002145. [PMID] 30694987.
2019
The Impact of Prior Laparotomy and Intra-abdominal Adhesions on Bowel and Mesenteric Injury Following Blunt Abdominal Trauma.
World journal of surgery. 43(2):457-465 [DOI] 10.1007/s00268-018-4792-6. [PMID] 30225563.
2019
The impact of standardized protocol implementation for surgical damage control and temporary abdominal closure after emergent laparotomy.
The journal of trauma and acute care surgery. 86(4):670-678 [DOI] 10.1097/TA.0000000000002170. [PMID] 30562327.
2018
A protocol for non-operative management of uncomplicated appendicitis.
The journal of trauma and acute care surgery. 84(2):358-364 [DOI] 10.1097/TA.0000000000001709. [PMID] 29370051.
2018
Anemia and blood transfusion in elderly trauma patients.
The Journal of surgical research. 229:288-293 [DOI] 10.1016/j.jss.2018.04.021. [PMID] 29937004.
2018
Autophagy: should it play a role in ICU management?
Current opinion in critical care. 24(2):112-117 [DOI] 10.1097/MCC.0000000000000486. [PMID] 29401174.
2018
Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients.
The journal of trauma and acute care surgery. 84(2):342-349 [DOI] 10.1097/TA.0000000000001758. [PMID] 29251709.
2018
Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group.
World journal of emergency surgery : WJES. 13 [DOI] 10.1186/s13017-018-0185-2. [PMID] 29946347.
2018
Can Specialized Pro-resolving Mediators Deliver Benefit Originally Expected from Fish Oil?
Current gastroenterology reports. 20(9) [DOI] 10.1007/s11894-018-0647-4. [PMID] 30078085.
2018
Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome.
Frontiers in immunology. 9 [DOI] 10.3389/fimmu.2018.01511. [PMID] 30013565.
2018
Chronic Critical Illness: Application of What We Know.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 33(1):39-45 [DOI] 10.1002/ncp.10024. [PMID] 29323761.
2018
Effect of Time to Operation on Value of Care in Acute Care Surgery.
World journal of surgery. 42(8):2356-2363 [DOI] 10.1007/s00268-018-4476-2. [PMID] 29352339.
2018
Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis.
Shock (Augusta, Ga.). 49(3):249-258 [DOI] 10.1097/SHK.0000000000000981. [PMID] 28885387.
2018
Geriatric traumatic brain injury-What we know and what we don’t.
The journal of trauma and acute care surgery. 85(4):788-798 [DOI] 10.1097/TA.0000000000001910. [PMID] 30256343.
2018
HDL Cholesterol Efflux is Impaired in Older Patients with Early Sepsis: A Subanalysis of a Prospective Pilot Study.
Shock (Augusta, Ga.). 50(1):66-70 [DOI] 10.1097/SHK.0000000000001030. [PMID] 29049133.
2018
HDL inflammatory index correlates with and predicts severity of organ failure in patients with sepsis and septic shock.
PloS one. 13(9) [DOI] 10.1371/journal.pone.0203813. [PMID] 30216360.
2018
Hypertonic saline resuscitation after emergent laparotomy and temporary abdominal closure.
The journal of trauma and acute care surgery. 84(2):350-357 [DOI] 10.1097/TA.0000000000001730. [PMID] 29140948.
2018
Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy.
Frontiers in immunology. 9 [DOI] 10.3389/fimmu.2018.00595. [PMID] 29670613.
2018
Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery.
Surgery. 164(2):178-184 [DOI] 10.1016/j.surg.2018.04.011. [PMID] 29807651.
2018
Raising concerns about the Sepsis-3 definitions.
World journal of emergency surgery : WJES. 13 [DOI] 10.1186/s13017-018-0165-6. [PMID] 29416555.
2018
Resuscitative Endovascular Balloon Occlusion of the Aorta: Implementation and Preliminary Results at an Academic Level I Trauma Center.
Journal of the American College of Surgeons. 227(1):127-133 [DOI] 10.1016/j.jamcollsurg.2018.03.042. [PMID] 29709584.
2018
Sepsis is associated with reduced spontaneous neutrophil migration velocity in human adults.
PloS one. 13(10) [DOI] 10.1371/journal.pone.0205327. [PMID] 30300408.
2018
Successful nonoperative management of uncomplicated appendicitis: predictors and outcomes.
The Journal of surgical research. 222:212-218.e2 [DOI] 10.1016/j.jss.2017.10.006. [PMID] 29146455.
2018
The effects of beta blockade and clonidine on persistent injury-associated anemia.
The Journal of surgical research. 230:175-180 [DOI] 10.1016/j.jss.2018.06.001. [PMID] 29960715.
2018
The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients.
The journal of trauma and acute care surgery. 85(2):247-255 [DOI] 10.1097/TA.0000000000001921. [PMID] 29613958.
2017
Acute Kidney Injury Following Exploratory Laparotomy and Temporary Abdominal Closure.
Shock (Augusta, Ga.). 48(1):5-10 [DOI] 10.1097/SHK.0000000000000825. [PMID] 28009772.
2017
Antibiotics May be Safely Discontinued Within One Week of Percutaneous Cholecystostomy.
World journal of surgery. 41(5):1239-1245 [DOI] 10.1007/s00268-016-3861-y. [PMID] 28050668.
2017
Characterization of hypoalbuminemia following temporary abdominal closure.
The journal of trauma and acute care surgery. 83(4):650-656 [DOI] 10.1097/TA.0000000000001553. [PMID] 28837537.
2017
Computed tomography evidence of fluid in the hernia sac predicts surgical site infection following mesh repair of acutely incarcerated ventral and groin hernias.
The journal of trauma and acute care surgery. 83(1):170-174 [DOI] 10.1097/TA.0000000000001503. [PMID] 28426559.
2017
Early bronchoalveolar lavage for intubated trauma patients with TBI or chest trauma.
Journal of critical care. 39:78-82 [DOI] 10.1016/j.jcrc.2017.02.010. [PMID] 28231518.
2017
Emergent laparotomy and temporary abdominal closure for the cirrhotic patient.
The Journal of surgical research. 210:108-114 [DOI] 10.1016/j.jss.2016.11.013. [PMID] 28457316.
2017
Exploring the Predictive Ability of Dysfunctional High-Density Lipoprotein for Adverse Outcomes in Emergency Department Patients with Sepsis: A Preliminary Investigation.
Shock (Augusta, Ga.). 48(5):539-544 [DOI] 10.1097/SHK.0000000000000887. [PMID] 28452909.
2017
Human Myeloid-derived Suppressor Cells are Associated With Chronic Immune Suppression After Severe Sepsis/Septic Shock.
Annals of surgery. 265(4):827-834 [DOI] 10.1097/SLA.0000000000001783. [PMID] 27163951.
2017
Improved outcomes following implementation of an acute gastrointestinal bleeding multidisciplinary protocol.
The journal of trauma and acute care surgery. 83(1):41-46 [DOI] 10.1097/TA.0000000000001295. [PMID] 27779592.
2017
Managing sepsis: Electronic recognition, rapid response teams, and standardized care save lives.
Journal of critical care. 40:296-302 [DOI] 10.1016/j.jcrc.2017.04.005. [PMID] 28412015.
2017
Microbial recognition and danger signals in sepsis and trauma.
Biochimica et biophysica acta. Molecular basis of disease. 1863(10 Pt B):2564-2573 [DOI] 10.1016/j.bbadis.2017.01.013. [PMID] 28115287.
2017
Neural network prediction of severe lower intestinal bleeding and the need for surgical intervention.
The Journal of surgical research. 212:42-47 [DOI] 10.1016/j.jss.2016.12.032. [PMID] 28550920.
2017
Nutrition Support for Persistent Inflammation, Immunosuppression, and Catabolism Syndrome.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 32(1_suppl):121S-127S [DOI] 10.1177/0884533616687502. [PMID] 28166447.
2017
Persistent Inflammation, Immunosuppression and Catabolism Syndrome.
Critical care clinics. 33(2):245-258 [DOI] 10.1016/j.ccc.2016.12.001. [PMID] 28284293.
2017
Persistent, Immunosuppression, Inflammation, Catabolism Syndrome and Diaphragmatic Dysfunction
Current Pulmonology Reports. 6(1):54-57 [DOI] 10.1007/s13665-017-0166-z.
2017
Postinjury Inflammation and Organ Dysfunction.
Critical care clinics. 33(1):167-191 [DOI] 10.1016/j.ccc.2016.08.006. [PMID] 27894496.
2017
Predicting appendiceal tumors among patients with appendicitis.
The journal of trauma and acute care surgery. 82(4):771-775 [DOI] 10.1097/TA.0000000000001378. [PMID] 28099380.
2017
Protein Turnover and Metabolism in the Elderly Intensive Care Unit Patient.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 32(1_suppl):112S-120S [DOI] 10.1177/0884533616686719. [PMID] 28388378.
2017
Routine surveillance cholangiography after percutaneous cholecystostomy delays drain removal and cholecystectomy.
The journal of trauma and acute care surgery. 82(2):351-355 [DOI] 10.1097/TA.0000000000001315. [PMID] 27893641.
2017
Sepsis and Critical Illness Research Center investigators: protocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients.
BMJ open. 7(7) [DOI] 10.1136/bmjopen-2016-015136. [PMID] 28765125.
2017
Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome.
Critical care medicine. 45(2):253-262 [DOI] 10.1097/CCM.0000000000002074. [PMID] 27632674.
2017
Summary Points and Consensus Recommendations From the International Protein Summit.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 32(1_suppl):142S-151S [DOI] 10.1177/0884533617693610. [PMID] 28388374.
2017
Temporary abdominal closure for trauma and intra-abdominal sepsis: Different patients, different outcomes.
The journal of trauma and acute care surgery. 82(2):345-350 [DOI] 10.1097/TA.0000000000001283. [PMID] 27787442.
2017
The authors reply.
Critical care medicine. 45(7):e740-e741 [DOI] 10.1097/CCM.0000000000002469. [PMID] 28622238.
2017
The Coalition for National Trauma Research supports the call for a national trauma research action plan.
The journal of trauma and acute care surgery. 82(3):637-645 [DOI] 10.1097/TA.0000000000001353. [PMID] 28030499.
2017
The effects of red cell transfusion donor age on nosocomial infection among trauma patients.
American journal of surgery. 214(4):672-676 [DOI] 10.1016/j.amjsurg.2017.07.004. [PMID] 28720216.
2017
The Epidemiology of Chronic Critical Illness After Severe Traumatic Injury at Two Level-One Trauma Centers.
Critical care medicine. 45(12):1989-1996 [DOI] 10.1097/CCM.0000000000002697. [PMID] 28837430.
2017
The Research Agenda for Trauma Critical Care
Intensive Care Medicine. 43(9):1340-1351 [DOI] 10.1007/s00134-017-4895-9.
2017
The role of NIGMS P50 sponsored team science in our understanding of multiple organ failure.
The journal of trauma and acute care surgery. 83(3):520-531 [DOI] 10.1097/TA.0000000000001587. [PMID] 28538636.
2017
Western Trauma Association Critical Decisions in Trauma: Management of adult blunt splenic trauma-2016 updates.
The journal of trauma and acute care surgery. 82(4):787-793 [DOI] 10.1097/TA.0000000000001323. [PMID] 27893644.
2017
What is the current role of laparoscopic lavage in perforated diverticulitis?
The journal of trauma and acute care surgery. 82(4):810-813 [DOI] 10.1097/TA.0000000000001390. [PMID] 28099377.
2016
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA).
World journal of emergency surgery : WJES. 11 [DOI] 10.1186/s13017-016-0089-y. [PMID] 27429642.
2016
Intubated Trauma Patients Receiving Prolonged Antibiotics for Pneumonia despite Negative Cultures: Predictors and Outcomes.
Surgical infections. 17(6):766-772 [PMID] 27635693.
View on: PubMed
2016
Nutritional Support in the Setting of Persistent Inflammation, Immunosuppression, and Catabolism Syndrome (Pics)
Current Surgery Reports. 4(9) [DOI] 10.1007/s40137-016-0152-3.
2016
Patterns of gene expression among murine models of hemorrhagic shock/trauma and sepsis.
Physiological genomics. 48(2):135-44 [DOI] 10.1152/physiolgenomics.00072.2015. [PMID] 26578697.
2016
Persistent Inflammation, Immunosuppression, and Catabolism: Evolution of Multiple Organ Dysfunction.
Surgical infections. 17(2):167-72 [DOI] 10.1089/sur.2015.184. [PMID] 26689501.
2016
Preoperative assessment of the risk for multiple complications after surgery.
Surgery. 160(2):463-72 [DOI] 10.1016/j.surg.2016.04.013. [PMID] 27238354.
2016
Sex-based differences in the genomic response, innate immunity, organ dysfunction, and clinical outcomes after severe blunt traumatic injury and hemorrhagic shock.
The journal of trauma and acute care surgery. 81(3):478-85 [DOI] 10.1097/TA.0000000000001113. [PMID] 27306446.
2016
The long-term burden of severe sepsis and septic shock: Sepsis recidivism and organ dysfunction.
The journal of trauma and acute care surgery. 81(3):525-32 [DOI] 10.1097/TA.0000000000001135. [PMID] 27398984.
2016
WSES Guidelines for the management of acute left sided colonic diverticulitis in the emergency setting.
World journal of emergency surgery : WJES. 11 [DOI] 10.1186/s13017-016-0095-0. [PMID] 27478494.
2015
A Detailed Characterization of the Dysfunctional Immunity and Abnormal Myelopoiesis Induced by Severe Shock and Trauma in the Aged.
Journal of immunology (Baltimore, Md. : 1950). 195(5):2396-407 [DOI] 10.4049/jimmunol.1500984. [PMID] 26246141.
2015
A Proposal for a Ct Driven Classification of Left Colon Acute Diverticulitis
World journal of emergency surgery : WJES. 10 [DOI] 10.1186/1749-7922-10-3. [PMID] 25922616.
2015
A Protocol for the Management of Adhesive Small Bowel Obstruction
Journal of Trauma and Acute Care Surgery. 78(1):13-19 [DOI] 10.1097/TA.0000000000000491. [PMID] 25539198.
2015
A Review of GM-CSF Therapy in Sepsis.
Medicine. 94(50) [DOI] 10.1097/MD.0000000000002044. [PMID] 26683913.
2015
Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock.
Critical care (London, England). 19 [DOI] 10.1186/s13054-015-0788-x. [PMID] 25880307.
2015
Clostridium difficile Infections after Blunt Trauma: A Different Patient Population?
Surgical infections. 16(4):421-7 [DOI] 10.1089/sur.2013.141. [PMID] 26207402.
2015
Cost and Mortality Associated With Postoperative Acute Kidney Injury.
Annals of surgery. 261(6):1207-14 [DOI] 10.1097/SLA.0000000000000732. [PMID] 24887982.
2015
Evolving paradigms in the nutritional support of critically ill surgical patients.
Current problems in surgery. 52(4):147-82 [DOI] 10.1067/j.cpsurg.2015.02.003. [PMID] 25946621.
2015
Measuring trauma system performance: Right patient, right place-Mission accomplished?
The journal of trauma and acute care surgery. 79(2):263-8 [DOI] 10.1097/TA.0000000000000660. [PMID] 26218695.
2015
Persistent inflammatory, immunosuppressed, catabolic syndrome (PICS): A new phenotype of multiple organ failure.
Journal of advanced nutritional and human metabolism. 1(1) [PMID] 26086042.
View on: PubMed
2015
Successful implementation of a packed red blood cell and fresh frozen plasma transfusion protocol in the surgical intensive care unit.
PloS one. 10(5) [DOI] 10.1371/journal.pone.0126895. [PMID] 26010247.
2015
The future of murine sepsis and trauma research models.
Journal of leukocyte biology. 98(6):945-52 [DOI] 10.1189/jlb.5MR0315-127R. [PMID] 26034205.
2014
A better understanding of why murine models of trauma do not recapitulate the human syndrome.
Critical care medicine. 42(6):1406-13 [DOI] 10.1097/CCM.0000000000000222. [PMID] 24413577.
2014
A Comparison of the Leukocyte Genomic Responses To Sterile Or Infectious Inflammation
Shock. 41(2)
2014
A Novel Drug for Treatment of Necrotizing Soft-Tissue Infections: A Randomized Clinical Trial.
JAMA surgery. 149(6):528-36 [DOI] 10.1001/jamasurg.2013.4841. [PMID] 24740134.
2014
Aged mice are unable to mount an effective myeloid response to sepsis.
Journal of immunology (Baltimore, Md. : 1950). 192(2):612-22 [DOI] 10.4049/jimmunol.1302109. [PMID] 24337739.
2014
Blunt cerebrovascular injury in rugby and other contact sports: case report and review of the literature.
World journal of emergency surgery : WJES. 9 [DOI] 10.1186/1749-7922-9-36. [PMID] 24872841.
2014
Computer versus paper system for recognition and management of sepsis in surgical intensive care.
The journal of trauma and acute care surgery. 76(2):311-7; discussion 318 [DOI] 10.1097/TA.0000000000000121. [PMID] 24458039.
2014
Current Concept of Abdominal Sepsis: Wses Position Paper
World journal of emergency surgery : WJES. 9(1) [DOI] 10.1186/1749-7922-9-22. [PMID] 24674057.
2014
Emergency Surgeon: ‘Last of the Mohicansandquot; 2014-2016 Editorial Policy Wses-Wjes: Position Papers, Guidelines, Courses, Books and Original Research; From Wjes Impact Factor To Wses Congress Impact Factor
World journal of emergency surgery : WJES. 9(1) [DOI] 10.1186/1749-7922-9-14. [PMID] 24484743.
2014
Emergency Surgeon: ‘Last of the Mohicansandquot; 2014-2016 Editorial Policy Wses-Wjes: Position Papers, Guidelines, Courses, Books and Original Research; From Wjes Impact Factor To Wses Congress Impact Factor (Vol 9, Pg 25, 2014)
World journal of emergency surgery : WJES. 9(1) [DOI] 10.1186/1749-7922-9-25. [PMID] 24708635.
2014
Gram Stain Can Be Used To Safely Discontinue Vancomycin Therapy for Early Pneumonia in the Trauma Intensive Care Unit
The American Surgeon. 80(12):1277-1279
2014
Host responses to sepsis vary in different low-lethality murine models.
PloS one. 9(5) [DOI] 10.1371/journal.pone.0094404. [PMID] 24788351.
2014
Oesophageal Injuries: Position Paper, Wses, 2013
World journal of emergency surgery : WJES. 9(1) [DOI] 10.1186/1749-7922-9-9. [PMID] 24447730.
2014
Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma.
The journal of trauma and acute care surgery. 76(1):21-9; discussion 29 [DOI] 10.1097/TA.0b013e3182ab1ab5. [PMID] 24368353.
2014
Postinjury Abdominal Compartment Syndrome: From Recognition To Prevention
Lancet. 384(9952):1466-1475
2014
Protective immunity and defects in the neonatal and elderly immune response to sepsis.
Journal of immunology (Baltimore, Md. : 1950). 192(7):3156-65 [DOI] 10.4049/jimmunol.1301726. [PMID] 24591376.
2014
The Lung Neutrophil Transcriptome After Trauma Influences the Worse Outcomes of the Old To Pneumonia
Critical Care Medicine. 42(12, S)
2013
A genomic analysis of Clostridium difficile infections in blunt trauma patients.
The journal of trauma and acute care surgery. 74(1):334-8 [DOI] 10.1097/TA.0b013e3182789426. [PMID] 23271108.
2013
Acute kidney injury is associated with early cytokine changes after trauma.
The journal of trauma and acute care surgery. 74(4):1005-13 [DOI] 10.1097/TA.0b013e31828586ec. [PMID] 23511138.
2013
Acute kidney injury is surprisingly common and a powerful predictor of mortality in surgical sepsis.
The journal of trauma and acute care surgery. 75(3):432-8 [DOI] 10.1097/TA.0b013e31829de6cd. [PMID] 24089113.
2013
Early diagnosis and evidence-based care of surgical sepsis.
Journal of intensive care medicine. 28(2):107-17 [DOI] 10.1177/0885066611408690. [PMID] 21747125.
2013
Identification and description of a novel murine model for polytrauma and shock.
Critical care medicine. 41(4):1075-85 [DOI] 10.1097/CCM.0b013e318275d1f9. [PMID] 23399937.
2013
Is there value in plasma cytokine measurements in patients with severe trauma and sepsis?
Methods (San Diego, Calif.). 61(1):3-9 [DOI] 10.1016/j.ymeth.2013.04.024. [PMID] 23669589.
2013
Just say no to intensive care unit starvation: a nutrition education program for surgery residents.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 28(3):387-91 [DOI] 10.1177/0884533613477136. [PMID] 23459609.
2013
National surgical quality improvement program underestimates the risk associated with mild and moderate postoperative acute kidney injury.
Critical care medicine. 41(11):2570-83 [DOI] 10.1097/CCM.0b013e31829860fc. [PMID] 23928835.
2013
Position paper: management of perforated sigmoid diverticulitis.
World journal of emergency surgery : WJES. 8(1) [DOI] 10.1186/1749-7922-8-55. [PMID] 24369826.
2013
Re: Mandatory exploration is not necessary for patients with acute diverticulitis and free intraperitoneal air.
The journal of trauma and acute care surgery. 74(5):1376-7 [DOI] 10.1097/TA.0b013e31828c31bf. [PMID] 23609295.
2013
Second Wses Convention, Wjes Impact Factor, and Emergency Surgery Worldwide
World journal of emergency surgery : WJES. 8(1) [DOI] 10.1186/1749-7922-8-15. [PMID] 23587370.
2013
Western Trauma Association critical decisions in trauma: evaluation and management of peripheral vascular injury, part II.
The journal of trauma and acute care surgery. 75(3):391-7 [DOI] 10.1097/TA.0b013e3182994b48. [PMID] 23928739.
2013
Western Trauma Association critical decisions in trauma: management of pancreatic injuries.
The journal of trauma and acute care surgery. 75(6):941-6 [DOI] 10.1097/TA.0b013e3182a96572. [PMID] 24256664.
2013
Western Trauma Association critical decisions in trauma: penetrating neck trauma.
The journal of trauma and acute care surgery. 75(6):936-40 [DOI] 10.1097/TA.0b013e31829e20e3. [PMID] 24256663.
2013
Wses Guidelines for Emergency Repair of Complicated Abdominal Wall Hernias
World journal of emergency surgery : WJES. 8(1) [DOI] 10.1186/1749-7922-8-50. [PMID] 24289453.
2012
Effect of Postoperative Acute Kidney Injury On Hospital Cost
Critical Care Medicine. 40
2012
Epidemiology of Sepsis in Surgical Patients
Surgical clinics of North America. 92(6):1425+-43 [DOI] 10.1016/j.suc.2012.08.009. [PMID] 23153877.
2012
Identification and Description of a Novel Murine Model for Polytrauma and Shock
Shock. 37
2012
Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care.
The journal of trauma and acute care surgery. 72(6):1491-501 [DOI] 10.1097/TA.0b013e318256e000. [PMID] 22695412.
2012
The identification of thyroid dysfunction in surgical sepsis.
The journal of trauma and acute care surgery. 73(6):1457-60 [DOI] 10.1097/TA.0b013e318270db2c. [PMID] 23188238.
2012
Tnfr1-Dependent Pulmonary Apoptosis During Ischemic Acute Kidney Injury
American Journal of Physiology-Lung Cellular and Molecular Physiology. 303(5):L449-L459 [DOI] 10.1152/ajplung.00301.2011. [PMID] 22728466.
2012
Western Trauma Association critical decisions in trauma: management of complicated diverticulitis.
The journal of trauma and acute care surgery. 73(6):1365-71 [DOI] 10.1097/TA.0b013e31827826d8. [PMID] 23188229.
2012
Western Trauma Association critical decisions in trauma: management of parapneumonic effusion.
The journal of trauma and acute care surgery. 73(6):1372-9 [DOI] 10.1097/TA.0b013e31825ff7e4. [PMID] 22902738.
2012
Western Trauma Association critical decisions in trauma: management of the mangled extremity.
The journal of trauma and acute care surgery. 72(1):86-93 [DOI] 10.1097/TA.0b013e318241ed70. [PMID] 22310120.
2012
Western Trauma Association critical decisions in trauma: resuscitative thoracotomy.
The journal of trauma and acute care surgery. 73(6):1359-63 [DOI] 10.1097/TA.0b013e318270d2df. [PMID] 23188227.
2011
Availability of acute care surgeons improves outcomes in patients requiring emergent colon surgery.
American journal of surgery. 202(6):837-42 [DOI] 10.1016/j.amjsurg.2011.07.006. [PMID] 22014648.
2011
Challenges to effective research in acute trauma resuscitation: consent and endpoints.
Shock (Augusta, Ga.). 35(2):107-13 [DOI] 10.1097/SHK.0b013e3181f7fd01. [PMID] 20926987.
2011
Computer protocol facilitates evidence-based care of sepsis in the surgical intensive care unit.
The Journal of trauma. 70(5):1153-66; discussion 1166 [DOI] 10.1097/TA.0b013e31821598e9. [PMID] 21610430.
2011
Evaluation and Management of Peripheral Vascular Injury. Part 1. Western Trauma Association/Critical Decisions in Trauma
Journal of Trauma. 70(6):1551-1556 [DOI] 10.1097/TA.0b013e31821b5bdd. [PMID] 21817992.
2011
Identification of cardiac dysfunction in sepsis with B-type natriuretic peptide.
Journal of the American College of Surgeons. 213(1):139-46; discussion 146 [DOI] 10.1016/j.jamcollsurg.2011.03.027. [PMID] 21514182.
2011
Nutrition support for the acute lung injury/adult respiratory distress syndrome patient: a review.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 26(1):14-25 [DOI] 10.1177/0884533610393255. [PMID] 21266693.
2011
Postinjury Resuscitation With Human Polymerized Hemoglobin Prolongs Early Survival: a Post Hoc Analysis
Journal of Trauma. 70(5 Suppl):S34-S37 [DOI] 10.1097/TA.0b013e31821a586e. [PMID] 21841568.
2011
Robotic telepresence: a helpful adjunct that is viewed favorably by critically ill surgical patients.
American journal of surgery. 202(6):843-7 [DOI] 10.1016/j.amjsurg.2011.08.001. [PMID] 22137142.
2011
Surgical sepsis and organ crosstalk: the role of the kidney.
The Journal of surgical research. 167(2):306-15 [DOI] 10.1016/j.jss.2010.11.923. [PMID] 21324390.
2011
The epidemiology of sepsis in general surgery patients.
The Journal of trauma. 70(3):672-80 [DOI] 10.1097/TA.0b013e31820e7803. [PMID] 21610358.
2011
The use of lactated ringer’s in shock resuscitation: the good, the bad and the ugly.
The Journal of trauma. 70(5 Suppl):S15-6 [DOI] 10.1097/TA.0b013e31821a4d6e. [PMID] 21841560.
2011
Western Trauma Association/critical decisions in trauma: operative management of adult blunt hepatic trauma.
The Journal of trauma. 71(1):1-5 [DOI] 10.1097/TA.0b013e318220b192. [PMID] 21818009.
2010
Compilation of recommendations from summit on increasing physician nutrition experts.
JPEN. Journal of parenteral and enteral nutrition. 34(6 Suppl):123S-32S [DOI] 10.1177/0148607110373485. [PMID] 21149844.
2010
Computerized clinical decision support improves mortality in intra abdominal surgical sepsis.
American journal of surgery. 200(6):839-43; discussion 843 [DOI] 10.1016/j.amjsurg.2010.07.036. [PMID] 21146030.
2010
Evaluation of empiric antibiotic use in surgical sepsis.
American journal of surgery. 200(6):776-82; discussion 782 [DOI] 10.1016/j.amjsurg.2010.09.001. [PMID] 21146020.
2010
Intestinal ischemic preconditioning after ischemia/reperfusion injury in rat intestine: profiling global gene expression patterns.
Digestive diseases and sciences. 55(7):1866-77 [DOI] 10.1007/s10620-009-0980-4. [PMID] 19779973.
2010
Performance of a computerized protocol for trauma shock resuscitation.
World journal of surgery. 34(2):216-22 [DOI] 10.1007/s00268-009-0309-7. [PMID] 20012614.
2010
Poloxamer 188 inhibition of ischemia/reperfusion injury: evidence for a novel anti-adhesive mechanism.
Annals of clinical and laboratory science. 40(2):115-25 [PMID] 20421622.
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2010
Presidential address: imagination trumps knowledge.
American journal of surgery. 200(6):671-7 [DOI] 10.1016/j.amjsurg.2010.05.009. [PMID] 21146000.
2010
Resuscitation beyond the abdominal compartment syndrome.
Current opinion in critical care. 16(6):570-4 [DOI] 10.1097/MCC.0b013e3283409d16. [PMID] 23361130.
2010
Sepsis in general surgery: the 2005-2007 national surgical quality improvement program perspective.
Archives of surgery (Chicago, Ill. : 1960). 145(7):695-700 [DOI] 10.1001/archsurg.2010.107. [PMID] 20644134.
2010
Therapeutic distant organ effects of regional hypothermia during mesenteric ischemia-reperfusion injury.
Journal of vascular surgery. 52(4):1003-14 [DOI] 10.1016/j.jvs.2010.05.088. [PMID] 20678877.
2010
Trauma.
Current opinion in critical care. 16(6):568-9 [DOI] 10.1097/MCC.0b013e3283409d30. [PMID] 23361129.
2010
What’s better?
JPEN. Journal of parenteral and enteral nutrition. 34(6):600-1 [DOI] 10.1177/0148607110376201. [PMID] 21097756.
2009
A multidisciplinary protocol improves electrolyte replacement and its effectiveness.
American journal of surgery. 198(6):911-5 [DOI] 10.1016/j.amjsurg.2009.04.032. [PMID] 19969151.
2009
Alpha-melanocyte stimulating hormone in critically injured trauma patients.
The Journal of trauma. 66(2):465-9 [DOI] 10.1097/TA.0b013e31818b1e04. [PMID] 19204522.
2009
Central venous pressure versus pulmonary artery catheter-directed shock resuscitation.
Shock (Augusta, Ga.). 32(5):463-70 [DOI] 10.1097/SHK.0b013e3181a20ba9. [PMID] 19829240.
2009
Early cytokine production risk stratifies trauma patients for multiple organ failure.
Journal of the American College of Surgeons. 209(3):320-31 [DOI] 10.1016/j.jamcollsurg.2009.05.002. [PMID] 19717036.
2009
Early hypothermia in severely injured trauma patients is a significant risk factor for multiple organ dysfunction syndrome but not mortality.
Annals of surgery. 249(5):845-50 [DOI] 10.1097/SLA.0b013e3181a41f6f. [PMID] 19387315.
2009
Human polymerized hemoglobin for the treatment of hemorrhagic shock when blood is unavailable: the USA multicenter trial.
Journal of the American College of Surgeons. 208(1):1-13 [DOI] 10.1016/j.jamcollsurg.2008.09.023. [PMID] 19228496.
2009
Monitoring trauma and intensive care unit resuscitation with tissue hemoglobin oxygen saturation.
Critical care (London, England). 13 Suppl 5 [DOI] 10.1186/cc8008. [PMID] 19951382.
2009
Postinjury abdominal compartment syndrome: are we winning the battle?
World journal of surgery. 33(6):1134-41 [DOI] 10.1007/s00268-009-0002-x. [PMID] 19343417.
2009
Postinjury multiple organ failure.
Injury. 40(9):912-8 [DOI] 10.1016/j.injury.2009.05.024. [PMID] 19541301.
2009
Sepsis in general surgery: a deadly complication.
American journal of surgery. 198(6):868-74 [DOI] 10.1016/j.amjsurg.2009.05.025. [PMID] 19969144.
2009
The evolving rationale for early enteral nutrition based on paradigms of multiple organ failure: a personal journey.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 24(3):297-304 [DOI] 10.1177/0884533609336604. [PMID] 19483059.
2009
The USA Multicenter Prehosptial Hemoglobin-based Oxygen Carrier Resuscitation Trial: scientific rationale, study design, and results.
Critical care clinics. 25(2):325-56, Table of Contents [DOI] 10.1016/j.ccc.2009.01.002. [PMID] 19341912.
2009
Tourniquets: another adjunct in damage control?
Annals of surgery. 249(1):8-9 [DOI] 10.1097/SLA.0b013e3181932329. [PMID] 19106668.
2009
Validation of a screening tool for the early identification of sepsis.
The Journal of trauma. 66(6):1539-46; discussion 1546 [DOI] 10.1097/TA.0b013e3181a3ac4b. [PMID] 19509612.
2009
Western Trauma Association critical decisions in trauma: nonoperative management of adult blunt hepatic trauma.
The Journal of trauma. 67(6):1144-8; discussion 1148 [DOI] 10.1097/TA.0b013e3181ba361f. [PMID] 20009658.
2008
Computerized clinical decision support for traumatic shock resuscitation.
Current opinion in critical care. 14(6):679-84 [DOI] 10.1097/MCC.0b013e328319654b. [PMID] 19005309.
2008
Computerized clinical decision support: a technology to implement and validate evidence based guidelines.
The Journal of trauma. 64(2):520-37 [DOI] 10.1097/TA.0b013e3181601812. [PMID] 18301226.
2008
Effects of poloxamer 188 on human PMN cells.
Surgery. 144(2):198-203 [DOI] 10.1016/j.surg.2008.05.001. [PMID] 18656626.
2008
Is there a role for aggressive use of fresh frozen plasma in massive transfusion of civilian trauma patients?
American journal of surgery. 196(6):948-58; discussion 958 [DOI] 10.1016/j.amjsurg.2008.07.043. [PMID] 19095115.
2008
Massive transfusion in trauma patients: tissue hemoglobin oxygen saturation predicts poor outcome.
The Journal of trauma. 64(4):1010-23 [DOI] 10.1097/TA.0b013e31816a2417. [PMID] 18404069.
2007
Acute lower extremity compartment syndrome (ALECS) screening protocol in critically ill trauma patients.
The Journal of trauma. 63(2):268-75 [PMID] 17693823.
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2007
Fresh frozen plasma should be given earlier to patients requiring massive transfusion.
The Journal of trauma. 62(1):112-9 [PMID] 17215741.
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2007
Hypertonic saline reverses stiffness in a Sprague-Dawley rat model of acute intestinal edema, leading to improved intestinal function.
Critical care medicine. 35(2):538-43 [PMID] 17205008.
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2007
Measurement of intestinal edema using an impedance analyzer circuit.
The Journal of surgical research. 138(1):106-10 [PMID] 17161426.
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2007
The practice of venous thromboembolism prophylaxis in the major trauma patient.
The Journal of trauma. 62(3):557-62; discussion 562 [PMID] 17414328.
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2007
Tissue oxygen saturation predicts the development of organ dysfunction during traumatic shock resuscitation.
The Journal of trauma. 62(1):44-54; discussion 54 [PMID] 17215732.
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2006
A multidisciplinary clinical pathway decreases rib fracture-associated infectious morbidity and mortality in high-risk trauma patients.
American journal of surgery. 192(6):806-11 [PMID] 17161098.
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2006
Conventional dose hypertonic saline provides optimal gut protection and limits remote organ injury after gut ischemia reperfusion.
The Journal of trauma. 61(1):66-73; discussion 73 [PMID] 16832251.
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2006
Early predictors of prolonged mechanical ventilation in major torso trauma patients who require resuscitation.
American journal of surgery. 192(6):822-7 [PMID] 17161101.
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2006
Hypertonic saline resuscitation prevents hydrostatically induced intestinal edema and ileus.
Critical care medicine. 34(6):1713-8 [PMID] 16625118.
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Inflammation and the Host Response to Injury, a large-scale collaborative project: patient-oriented research core–standard operating procedures for clinical care. III. Guidelines for shock resuscitation.
The Journal of trauma. 61(1):82-9 [PMID] 16832253.
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2006
Management of distal femoral and popliteal arterial injuries: an update.
American journal of surgery. 192(6):773-8 [PMID] 17161092.
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2006
Nutrition support in adult trauma patients.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 21(5):421-9 [PMID] 16998141.
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2006
Risk factors for hepatic morbidity following nonoperative management: multicenter study.
Archives of surgery (Chicago, Ill. : 1960). 141(5):451-8; discussion 458 [PMID] 16702516.
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2006
The impact of diabetes on outcome in traumatically injured patients: an analysis of the National Trauma Data Bank.
American journal of surgery. 192(6):710-4 [PMID] 17161080.
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2005
Complications of nonoperative management of high-grade blunt hepatic injuries.
The Journal of trauma. 59(5):1066-71 [PMID] 16385280.
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2005
Effects of primary and secondary intra-abdominal hypertension on mesenteric lymph flow: implications for the abdominal compartment syndrome.
Shock (Augusta, Ga.). 23(6):571-5 [PMID] 15897812.
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2005
Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis.
The Journal of trauma. 59(5):1092-8 [PMID] 16385285.
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2005
Immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion.
The Journal of trauma. 58(3):455-61; discussion 461 [PMID] 15761336.
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2005
Intra-abdominal hypertension: not just a surgical critical care curiosity.
Critical care medicine. 33(2):447-9 [PMID] 15699854.
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2005
Ischemic preconditioning protects against gut dysfunction and mucosal injury after ischemia/reperfusion injury.
Shock (Augusta, Ga.). 23(3):258-63 [PMID] 15718925.
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2005
Ketamine inhibits lipopolysacharide (LPS) induced gastric luminal fluid accumulation.
The Journal of surgical research. 127(2):203-7 [PMID] 15916771.
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2005
Peroxisome proliferator-activated receptor gamma mediates protection against cyclooxygenase-2-induced gut dysfunction in a rodent model of mesenteric ischemia/reperfusion.
Shock (Augusta, Ga.). 24(5):462-9 [PMID] 16247333.
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2005
Prehospital physiologic data and lifesaving interventions in trauma patients.
Military medicine. 170(1):7-13 [PMID] 15724847.
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2005
Resuscitation-induced gut edema and intestinal dysfunction.
The Journal of trauma. 58(2):264-70 [PMID] 15706186.
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Resuscitation-induced intestinal edema decreases the stiffness and residual stress of the intestine.
Shock (Augusta, Ga.). 24(2):165-70 [PMID] 16044088.
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Enteral glutamine but not alanine maintains small bowel barrier function after ischemia/reperfusion injury in rats.
Shock (Augusta, Ga.). 21(5):433-7 [PMID] 15087819.
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2004
Hypertonic saline prevents inflammation, injury, and impaired intestinal transit after gut ischemia/reperfusion by inducing heme oxygenase 1 enzyme.
The Journal of trauma. 56(4):749-58; discussion 758 [PMID] 15187737.
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Preload optimization using “starling curve” generation during shock resuscitation: can it be done?
Shock (Augusta, Ga.). 21(4):300-5 [PMID] 15179128.
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Superior mesenteric artery occlusion models shock-induced gut ischemia-reperfusion.
The Journal of surgical research. 116(1):145-50 [PMID] 14732361.
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The next generation in shock resuscitation.
Lancet (London, England). 363(9425):1988-96 [PMID] 15194260.
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Abdominal compartment syndrome: the cause or effect of postinjury multiple organ failure.
Shock (Augusta, Ga.). 20(6):483-92 [PMID] 14625470.
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Both primary and secondary abdominal compartment syndrome can be predicted early and are harbingers of multiple organ failure.
The Journal of trauma. 54(5):848-59; discussion 859 [PMID] 12777898.
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Distal aortic perfusion and cerebrospinal fluid drainage for thoracoabdominal and descending thoracic aortic repair: ten years of organ protection.
Annals of surgery. 238(3):372-80; discussion 380 [PMID] 14501503.
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2003
Goal-oriented shock resuscitation for major torso trauma: what are we learning?
Current opinion in critical care. 9(4):292-9 [PMID] 12883284.
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2003
Gut dysfunction and intolerance to enteral nutrition in critically ill patients.
Nestle Nutrition workshop series. Clinical & performance programme. 8:149-65; discussion 165 [PMID] 12968453.
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Hypothermia protects against gut ischemia/reperfusion-induced impaired intestinal transit by inducing heme oxygenase-1.
The Journal of surgical research. 115(1):48-55 [PMID] 14572772.
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2003
Morbidity from rib fractures increases after age 45.
Journal of the American College of Surgeons. 196(4):549-55 [PMID] 12691929.
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2003
Patients with impending abdominal compartment syndrome do not respond to early volume loading.
American journal of surgery. 186(6):602-7; discussion 607 [PMID] 14672765.
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2003
Regional hypothermia reduces mucosal NF-kappaB and PMN priming via gut lymph during canine mesenteric ischemia/reperfusion.
The Journal of surgical research. 115(1):121-6 [PMID] 14572782.
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Supranormal trauma resuscitation causes more cases of abdominal compartment syndrome.
Archives of surgery (Chicago, Ill. : 1960). 138(6):637-42; discussion 642 [PMID] 12799335.
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Vacuum-assisted wound closure achieves early fascial closure of open abdomens after severe trauma.
The Journal of trauma. 55(6):1155-60; discussion 1160 [PMID] 14676665.
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2002
Alpha-melanocyte-stimulating hormone protects against mesenteric ischemia-reperfusion injury.
American journal of physiology. Gastrointestinal and liver physiology. 282(6):G1059-68 [PMID] 12016132.
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2002
Normal versus supranormal oxygen delivery goals in shock resuscitation: the response is the same.
The Journal of trauma. 53(5):825-32 [PMID] 12435930.
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2002
Postinjury enteral tolerance is reliably achieved by a standardized protocol.
The Journal of surgical research. 104(1):70-5 [PMID] 11971680.
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2002
Secondary abdominal compartment syndrome is an elusive early complication of traumatic shock resuscitation.
American journal of surgery. 184(6):538-43; discussion 543 [PMID] 12488160.
View on: PubMed
2002
Specific intraluminal nutrients alter mucosal blood flow during gut ischemia/reperfusion.
JPEN. Journal of parenteral and enteral nutrition. 26(4):226-9 [PMID] 12090686.
View on: PubMed
2002
Standardized trauma resuscitation: female hearts respond better.
Archives of surgery (Chicago, Ill. : 1960). 137(5):578-83; discussion 583 [PMID] 11982472.
View on: PubMed
2002
The type of sodium-coupled solute modulates small bowel mucosal injury, transport function, and ATP after ischemia/reperfusion injury in rats.
Gastroenterology. 123(3):810-6 [PMID] 12198707.
View on: PubMed
2002
Treatment of aspiration in intensive care unit patients.
JPEN. Journal of parenteral and enteral nutrition. 26(6 Suppl):S69-74; discussion S74 [PMID] 12405626.
View on: PubMed

Grants

Sep 2018 ACTIVE
Arsenal Medical REVIVE Trial Data Monitoring Committee
Role: Principal Investigator
Funding: AVANIA via US ARMY MED RES ACQUISITION
Jul 2018 – Jun 2021
Cardiac Dysfunction in Older Sepsis Survivors
Role: Other
Funding: AMER HEART ASSOCIATION
Jun 2018 ACTIVE
OR-DRPD-ROF2018: The LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P) Trial
Role: Co-Investigator
Funding: UF RESEARCH
Jun 2018 – May 2020
PICS: A New Horizon for Surgical Critical Care
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Jun 2017 – May 2018
PICS: A New Horizon for Surgical Critical Care
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Sep 2016 – Aug 2020
The Role of Dysfunctional HDL in Sepsis
Role: Other
Funding: NATL INST OF HLTH NIGMS
Jun 2016 – May 2017
PICS: A New Horizon for Surgical Critical Care
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Jun 2015 – May 2016
PICS: A New Horizon for Surgical Critical Care
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Apr 2015 – Jan 2021
Hematopoietic Stem Cell Dysfunction in the Elderly after Severe Injury
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Sep 2014 – Jun 2019
P50 Department Committment – PICS: A New Horizon for Surgical Critical Care
Role: Principal Investigator
Funding: FL CLINICAL PRACTICE ASSO
Sep 2014 – May 2019
DSR MATCH – P50 PICS: A NEW HORIZON FOR SURGICAL CRITICALCARE
Role: Principal Investigator
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS

Education

Chief Resident – Surgery
1985 · University of Colorado Health Science Center
M.D.
1979 · University of Pittsburgh

Teaching Profile

Courses Taught
2018
MDC7600 Surgery Clerkship
2018
MDC7602 Senior Surgery Clerk
2018
MDC6001 Intro Clin Practice

Contact Details

Phones:
Business:
(352) 273-5670