Alicia Mohr, MD, FACS, FCCM
Edward R. Woodward Professor And Chief, Acute Care Surgery; Program Director Acute Care Surgery Fellowship Program; Associate Program Director Surgical Critical Care Fellowship
About Alicia Mohr
I am a professor in the University of Florida Department of Surgery and the chief of the UF Division of Acute Care Surgery. As an acute care surgeon, I cover trauma emergency general surgery and the ICU. I see patients in the emergency department, operating room and surgical intensive care units for all traumatic injuries and emergency general surgical conditions, including appendicitis, cholecystitis, bowel obstruction and necrotizing soft tissue infection. Working in emergency care is a multidisciplinary endeavor I find extremely rewarding. My goal as a physician is to provide optimal care, recognizing and acting fast on surgical emergencies.
I earned my medical degree from the New Jersey Medical School and completed my general surgery residency training at the affiliated University Hospital, followed by a surgical critical care fellowship at the University of North Carolina Chapel Hill. I am board certified in surgery and surgical critical care by the American Board of Surgery.
Prior to joining UF Health, I worked as an associate professor of surgery in the division of trauma/critical care at Rutgers New Jersey Medical School’s department of surgery and progressed leadership through the University Hospital in Newark, New Jersey. I went from medical director of the trauma/surgical progressive care unit to program director for the surgical critical care fellowship and director of the surgical intensive care unit. Additionally, I worked as the director of trauma/critical care research at Hackensack University Medical Center in New Jersey.
My clinical interests include trauma surgery, surgical critical care and emergency general surgery. These three disciplines encompass acute care surgery, the comprehensive care of emergent, critically-ill surgical patients. My research interests are both in basic science as well as translational. I currently am examining the impact of stress following injury and shock on erythropoiesis. My research is NIH funded, where I was also a recipient of a NIH mentored research grant. I simultaneously was awarded by the American Association for the Surgery of Trauma/American College of Surgeons Clowes to support further research.
In my free time, I enjoy being outdoors, traveling and watching football.
Teaching Profile
Courses Taught
2018
MDC7600 Surgery Clerkship
2018
MDT7090 Elective Topics
2018
MDC7602 Senior Surgery Clerk
2018
MDC6001 Intro Clin Practice
Board Certifications
-
SurgeryAmerican Board of Surgery
-
Surgical Critical CareAmerican Board of Surgery
Clinical Profile
Subspecialties
- Critical Care Surgery
Areas of Interest
- Acute respiratory distress syndrome
- Anemia
- Traumatic Injury
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0003-1732-1313
Publications
2024
Acute Emergence of the Intestinal Pathobiome after Postinjury Pneumonia
Journal of Trauma and Acute Care Surgery.
[DOI] 10.1097/ta.0000000000004300.
2024
Exosomal microRNA following severe trauma: Role in bone marrow dysfunction.
The journal of trauma and acute care surgery.
96(4):548-556
[DOI] 10.1097/TA.0000000000004225.
[PMID] 38151766.
2024
Gut mycobiome dysbiosis after sepsis and trauma.
Critical care (London, England).
28(1)
[DOI] 10.1186/s13054-023-04780-4.
[PMID] 38212826.
2024
Multicompartmental Trauma Induces Persistent Inflammation and Organ Injury.
The Journal of surgical research.
293:266-273
[DOI] 10.1016/j.jss.2023.08.033.
[PMID] 37804796.
2024
Posttraumatic pneumonia exacerbates bone marrow erythropoietic dysfunction.
The journal of trauma and acute care surgery.
96(1):17-25
[DOI] 10.1097/TA.0000000000004157.
[PMID] 37853556.
2024
Weight-based enoxaparin thromboprophylaxis in young trauma patients: analysis of the CLOTT-1 registry.
Trauma surgery & acute care open.
9(1)
[DOI] 10.1136/tsaco-2023-001230.
[PMID] 38420604.
2023
A narrative review of ergonomic problems, principles, and potential solutions in surgical operations.
Surgery.
174(2):214-221
[DOI] 10.1016/j.surg.2023.04.003.
[PMID] 37202309.
2023
Anemia Recovery After Lung Contusion, Hemorrhagic Shock, and Chronic Stress Is Gender-Specific in a Rat Model.
Surgical infections.
24(9):773-781
[DOI] 10.1089/sur.2023.154.
[PMID] 37903014.
2023
Anemia Recovery after Trauma: A Longitudinal Study.
Surgical infections.
24(1):39-45
[DOI] 10.1089/sur.2022.299.
[PMID] 36579920.
2023
Bone Marrow Adipokine Expression Was Associated With Decreased Erythroid Colony Growth After Trauma
The American Surgeon™.
89(4):558-565
[DOI] 10.1177/00031348221135772.
2023
Chronic Critical Illness in Patients With Sepsis is Associated With Persistent Anemia, Inflammation, and Impaired Functional Outcomes
The American Surgeon™.
89(6):2563-2571
[DOI] 10.1177/00031348221104252.
[PMID] 35593749.
2023
Chronic mesenteric ischemia-induced intestinal dysbiosis resolved after revascularization.
Journal of vascular surgery cases and innovative techniques.
9(2)
[DOI] 10.1016/j.jvscit.2022.101084.
[PMID] 36970136.
2023
EFFECTS OF TRAUMA PLASMA-DERIVED EXOSOMES ON HEMATOPOIETIC PROGENITOR CELLS.
Shock (Augusta, Ga.).
59(4):591-598
[DOI] 10.1097/SHK.0000000000002094.
[PMID] 36772985.
2023
Multicompartmental trauma alters bone marrow erythroblastic islands.
The journal of trauma and acute care surgery.
94(2):197-204
[DOI] 10.1097/TA.0000000000003821.
[PMID] 36652391.
2023
Multicompartmental traumatic injury and the microbiome: Shift to a pathobiome.
The journal of trauma and acute care surgery.
94(1):15-22
[DOI] 10.1097/TA.0000000000003803.
[PMID] 36203239.
2023
Multicompartmental traumatic injury induces sex-specific alterations in the gut microbiome.
The journal of trauma and acute care surgery.
95(1):30-38
[DOI] 10.1097/TA.0000000000003939.
[PMID] 36872509.
2023
Narrowing the Gap: Preclinical Trauma with Postinjury Sepsis Model with Increased Clinical Relevance.
Shock (Augusta, Ga.).
60(2):272-279
[DOI] 10.1097/SHK.0000000000002161.
[PMID] 37310788.
2023
Retrospective value assessment of a dedicated, trauma hybrid operating room.
The journal of trauma and acute care surgery.
94(6):814-822
[DOI] 10.1097/TA.0000000000003873.
[PMID] 36727772.
2023
Sex-specific intestinal dysbiosis persists after multicompartmental injury.
Surgery.
174(6):1453-1462
[DOI] 10.1016/j.surg.2023.08.023.
[PMID] 37833155.
2023
Survival and neurologic outcomes following aortic occlusion for trauma and hemorrhagic shock in a hybrid operating room.
Research square.
[DOI] 10.21203/rs.3.rs-2459030/v1.
[PMID] 36711502.
2023
Survival and neurologic outcomes following aortic occlusion for trauma and hemorrhagic shock in a hybrid operating room.
World journal of emergency surgery : WJES.
18(1)
[DOI] 10.1186/s13017-023-00484-w.
[PMID] 36959585.
2023
The Intestinal Microbiome after Traumatic Injury.
Microorganisms.
11(8)
[DOI] 10.3390/microorganisms11081990.
[PMID] 37630549.
2023
The persistent inflammation, immunosuppression, and catabolism syndrome 10 years later.
The journal of trauma and acute care surgery.
95(5):790-799
[DOI] 10.1097/TA.0000000000004087.
[PMID] 37561664.
2022
Adrenergic Modulation of Erythropoiesis After Trauma.
Frontiers in physiology.
13
[DOI] 10.3389/fphys.2022.859103.
[PMID] 35514362.
2022
Estimated vs measured energy expenditure in ventilated surgical-trauma critically ill patients.
JPEN. Journal of parenteral and enteral nutrition.
46(6):1431-1440
[DOI] 10.1002/jpen.2314.
[PMID] 34921708.
2022
Impact of Empiric Linezolid for Necrotizing Soft Tissue Infections on Duration of Methicillin-Resistant Staphylococcus aureus-Active Therapy.
Surgical infections.
23(3):313-317
[DOI] 10.1089/sur.2021.329.
[PMID] 35133888.
2022
Ineffective Erythropoietin Response to Anemia in Sepsis.
Surgical infections.
23(2):142-149
[DOI] 10.1089/sur.2021.152.
[PMID] 34958257.
2022
Mechanisms of improved erythroid progenitor growth with removal of chronic stress after trauma.
Surgery.
172(2):759-765
[DOI] 10.1016/j.surg.2022.04.056.
[PMID] 35672167.
2022
Sepsis-Induced Myopathy and Gut Microbiome Dysbiosis: Mechanistic Links and Therapeutic Targets.
Shock (Augusta, Ga.).
57(1):15-23
[DOI] 10.1097/SHK.0000000000001843.
[PMID] 34726875.
2022
Sex differences associate with late microbiome alterations after murine surgical sepsis.
The journal of trauma and acute care surgery.
93(2):137-146
[DOI] 10.1097/TA.0000000000003599.
[PMID] 35324554.
2022
Transcriptomic Changes Within Human Bone Marrow After Severe Trauma.
Shock (Augusta, Ga.).
57(1):24-30
[DOI] 10.1097/SHK.0000000000001826.
[PMID] 34172608.
2021
A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis.
Frontiers in immunology.
12
[DOI] 10.3389/fimmu.2021.696536.
[PMID] 34484194.
2021
Biomarker Evidence of the Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS) in Chronic Critical Illness (CCI) After Surgical Sepsis.
Annals of surgery.
274(4):664-673
[DOI] 10.1097/SLA.0000000000005067.
[PMID] 34506322.
2021
Chronic Critical Illness Elicits a Unique Circulating Leukocyte Transcriptome in Sepsis Survivors.
Journal of clinical medicine.
10(15)
[DOI] 10.3390/jcm10153211.
[PMID] 34361995.
2021
Clinical Impact of a Dedicated Trauma Hybrid Operating Room.
Journal of the American College of Surgeons.
232(4):560-570
[DOI] 10.1016/j.jamcollsurg.2020.11.008.
[PMID] 33227422.
2021
Distinct immunologic endotypes are associated with clinical trajectory after severe blunt trauma and hemorrhagic shock.
The journal of trauma and acute care surgery.
90(2):257-267
[DOI] 10.1097/TA.0000000000003029.
[PMID] 33214489.
2021
Dysregulated Immunity and Immunotherapy after Sepsis
Journal of Clinical Medicine.
10(8)
[DOI] 10.3390/jcm10081742.
[PMID] 33920518.
2021
Enteral Nutrition Administration Record Prescribing Process Using Computerized Order Entry: A New Paradigm and Opportunities to Improve Outcomes in Critically Ill Patients.
JPEN. Journal of parenteral and enteral nutrition.
45(3):507-517
[DOI] 10.1002/jpen.1870.
[PMID] 32384191.
2021
Identification of unique microRNA expression patterns in bone marrow hematopoietic stem and progenitor cells after hemorrhagic shock and multiple injuries in young and old adult mice.
The journal of trauma and acute care surgery.
91(4):692-699
[DOI] 10.1097/TA.0000000000003350.
[PMID] 34252063.
2021
Mediators of Prolonged Hematopoietic Progenitor Cell Mobilization After Severe Trauma.
The Journal of surgical research.
260:315-324
[DOI] 10.1016/j.jss.2020.11.084.
[PMID] 33373851.
2021
Optimal Antibiotic Duration for Bloodstream Infections Secondary to Intraabdominal Infection.
The Journal of surgical research.
260:82-87
[DOI] 10.1016/j.jss.2020.10.029.
[PMID] 33326932.
2021
Prolonged Chronic Stress and Persistent Iron Dysregulation Prevent Anemia Recovery Following Trauma.
The Journal of surgical research.
267:320-327
[DOI] 10.1016/j.jss.2021.05.034.
[PMID] 34186308.
2021
Septic Stability? Gut Microbiota in Young Adult Mice Maintains Overall Stability After Sepsis Compared to Old Adult Mice.
Shock (Augusta, Ga.).
55(4):519-525
[DOI] 10.1097/SHK.0000000000001648.
[PMID] 32826817.
2021
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.
Shock (Augusta, Ga.).
55(5):587-595
[DOI] 10.1097/SHK.0000000000001671.
[PMID] 33021571.
2021
Stress-related changes in the gut microbiome after trauma.
The journal of trauma and acute care surgery.
91(1):192-199
[DOI] 10.1097/TA.0000000000003209.
[PMID] 34144563.
2021
The Effect of Aging Physiology on Critical Care.
Critical care clinics.
37(1):135-150
[DOI] 10.1016/j.ccc.2020.08.006.
[PMID] 33190766.
2021
The Hematopoietic Stem/Progenitor Cell Response to Hemorrhage, Injury, and Sepsis: A Review of Pathophysiology.
Shock (Augusta, Ga.).
56(1):30-41
[DOI] 10.1097/SHK.0000000000001699.
[PMID] 33234838.
2021
The role of bone marrow microRNA (miR) in erythropoietic dysfunction after severe trauma.
Surgery.
169(5):1206-1212
[DOI] 10.1016/j.surg.2020.11.029.
[PMID] 33413921.
2021
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
35(2)
[DOI] 10.1096/fj.202002150R.
[PMID] 33140449.
2020
Abdominal sepsis patients have a high incidence of chronic critical illness with dismal long-term outcomes
The American Journal of Surgery.
220(6):1467-1474
[DOI] 10.1016/j.amjsurg.2020.07.016.
[PMID] 32807383.
2020
Artificial Intelligence and Surgical Decision-making.
JAMA surgery.
155(2):148-158
[DOI] 10.1001/jamasurg.2019.4917.
[PMID] 31825465.
2020
Audiovisual Modules to Enhance Informed Consent in the ICU: A Pilot Study.
Critical care explorations.
2(12)
[DOI] 10.1097/CCE.0000000000000278.
[PMID] 33251517.
2020
Delayed interhospital transfer of critically ill patients with surgical sepsis.
The journal of trauma and acute care surgery.
88(1):169-175
[DOI] 10.1097/TA.0000000000002476.
[PMID] 31856021.
2020
Effect of Beta-Blockade on the Expression of Regulatory MicroRNA after Severe Trauma and Chronic Stress.
Journal of the American College of Surgeons.
230(1):121-129
[DOI] 10.1016/j.jamcollsurg.2019.09.011.
[PMID] 31672639.
2020
Identification of Unique mRNA and miRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells After Trauma in Older Adults.
Frontiers in immunology.
11
[DOI] 10.3389/fimmu.2020.01289.
[PMID] 32670283.
2020
Impact of Injury Severity on the Inflammatory State and Severe Anemia.
The Journal of surgical research.
248:109-116
[DOI] 10.1016/j.jss.2019.10.046.
[PMID] 31881381.
2020
Modulation of the HGF/c-Met Axis Impacts Prolonged Hematopoietic Progenitor Mobilization Following Trauma and Chronic Stress.
Shock (Augusta, Ga.).
54(4):482-487
[DOI] 10.1097/SHK.0000000000001506.
[PMID] 31904616.
2020
Older Sepsis Survivors Suffer Persistent Disability Burden and Poor Long-Term Survival.
Journal of the American Geriatrics Society.
68(9):1962-1969
[DOI] 10.1111/jgs.16435.
[PMID] 32294254.
2020
Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study.
Critical care (London, England).
24(1)
[DOI] 10.1186/s13054-020-02917-3.
[PMID] 32381107.
2020
The effects of selective beta-adrenergic blockade on bone marrow dysfunction following severe trauma and chronic stress
The American Journal of Surgery.
220(5):1312-1318
[DOI] 10.1016/j.amjsurg.2020.06.058.
[PMID] 32741547.
2020
Vitamin D status is associated with hepcidin and hemoglobin concentrations in patients with severe traumatic injury.
The journal of trauma and acute care surgery.
89(6):1124-1130
[DOI] 10.1097/TA.0000000000002895.
[PMID] 32769953.
2019
Chronic stress induces persistent low-grade inflammation.
American journal of surgery.
218(4):677-683
[DOI] 10.1016/j.amjsurg.2019.07.006.
[PMID] 31378316.
2019
Current Epidemiology of Surgical Sepsis: Discordance Between Inpatient Mortality and 1-year Outcomes.
Annals of surgery.
270(3):502-510
[DOI] 10.1097/SLA.0000000000003458.
[PMID] 31356275.
2019
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis.
Critical care (London, England).
23(1)
[DOI] 10.1186/s13054-019-2628-x.
[PMID] 31722736.
2019
Occult bowel injury after blunt abdominal trauma
The American Journal of Surgery.
218(2):266-270
[DOI] 10.1016/j.amjsurg.2018.11.018.
[PMID] 30509454.
2019
Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model.
Critical care medicine.
47(11):e919-e929
[DOI] 10.1097/CCM.0000000000003926.
[PMID] 31389840.
2019
Persistent inflammation and anemia among critically ill septic patients.
The journal of trauma and acute care surgery.
86(2):260-267
[DOI] 10.1097/TA.0000000000002147.
[PMID] 30489504.
2019
Persistently Elevated Glucagon-Like Peptide-1 Levels among Critically Ill Surgical Patients after Sepsis and Development of Chronic Critical Illness and Dismal Long-Term Outcomes.
Journal of the American College of Surgeons.
229(1):58-67.e1
[DOI] 10.1016/j.jamcollsurg.2019.04.014.
[PMID] 30991107.
2019
Systemic Regulation of Bone Marrow Stromal Cytokines After Severe Trauma
Journal of Surgical Research.
243:220-228
[DOI] 10.1016/j.jss.2019.05.033.
[PMID] 31207479.
2019
The effects of propranolol and clonidine on bone marrow expression of hematopoietic cytokines following trauma and chronic stress.
American journal of surgery.
218(5):858-863
[DOI] 10.1016/j.amjsurg.2019.02.023.
[PMID] 30827533.
2019
The Impact of Prior Laparotomy and Intra-abdominal Adhesions on Bowel and Mesenteric Injury Following Blunt Abdominal Trauma.
World journal of surgery.
43(2):457-465
[DOI] 10.1007/s00268-018-4792-6.
[PMID] 30225563.
2019
The impact of standardized protocol implementation for surgical damage control and temporary abdominal closure after emergent laparotomy.
The journal of trauma and acute care surgery.
86(4):670-678
[DOI] 10.1097/TA.0000000000002170.
[PMID] 30562327.
2018
A protocol for non-operative management of uncomplicated appendicitis.
The journal of trauma and acute care surgery.
84(2):358-364
[DOI] 10.1097/TA.0000000000001709.
[PMID] 29370051.
2018
Anemia and blood transfusion in elderly trauma patients.
The Journal of surgical research.
229:288-293
[DOI] 10.1016/j.jss.2018.04.021.
[PMID] 29937004.
2018
Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients.
The journal of trauma and acute care surgery.
84(2):342-349
[DOI] 10.1097/TA.0000000000001758.
[PMID] 29251709.
2018
Dysregulated myelopoiesis and hematopoietic function following acute physiologic insult.
Current opinion in hematology.
25(1):37-43
[DOI] 10.1097/MOH.0000000000000395.
[PMID] 29035909.
2018
Effect of Time to Operation on Value of Care in Acute Care Surgery.
World journal of surgery.
42(8):2356-2363
[DOI] 10.1007/s00268-018-4476-2.
[PMID] 29352339.
2018
Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis.
Shock (Augusta, Ga.).
49(3):249-258
[DOI] 10.1097/SHK.0000000000000981.
[PMID] 28885387.
2018
Hypertonic saline resuscitation after emergent laparotomy and temporary abdominal closure.
The journal of trauma and acute care surgery.
84(2):350-357
[DOI] 10.1097/TA.0000000000001730.
[PMID] 29140948.
2018
Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy.
Frontiers in immunology.
9
[DOI] 10.3389/fimmu.2018.00595.
[PMID] 29670613.
2018
Mouse Injury Model of Polytrauma and Shock.
Methods in molecular biology (Clifton, N.J.).
1717:1-15
[DOI] 10.1007/978-1-4939-7526-6_1.
[PMID] 29468579.
2018
Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery
Surgery.
164(2):178-184
[DOI] 10.1016/j.surg.2018.04.011.
[PMID] 29807651.
2018
Persistent injury-associated anemia and aging: Novel insights.
The journal of trauma and acute care surgery.
84(3):490-496
[DOI] 10.1097/TA.0000000000001766.
[PMID] 29466280.
2018
Persistent injury-associated anemia in aged rats.
Experimental gerontology.
103:63-68
[DOI] 10.1016/j.exger.2018.01.001.
[PMID] 29307734.
2018
Resuscitative Endovascular Balloon Occlusion of the Aorta: Implementation and Preliminary Results at an Academic Level I Trauma Center.
Journal of the American College of Surgeons.
227(1):127-133
[DOI] 10.1016/j.jamcollsurg.2018.03.042.
[PMID] 29709584.
2018
Successful nonoperative management of uncomplicated appendicitis: predictors and outcomes.
The Journal of surgical research.
222:212-218.e2
[DOI] 10.1016/j.jss.2017.10.006.
[PMID] 29146455.
2018
The effects of beta blockade and clonidine on persistent injury-associated anemia.
The Journal of surgical research.
230:175-180
[DOI] 10.1016/j.jss.2018.06.001.
[PMID] 29960715.
2018
The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients.
The journal of trauma and acute care surgery.
85(2):247-255
[DOI] 10.1097/TA.0000000000001921.
[PMID] 29613958.
2017
Acute Kidney Injury Following Exploratory Laparotomy and Temporary Abdominal Closure.
Shock (Augusta, Ga.).
48(1):5-10
[DOI] 10.1097/SHK.0000000000000825.
[PMID] 28009772.
2017
Antibiotics May be Safely Discontinued Within One Week of Percutaneous Cholecystostomy.
World journal of surgery.
41(5):1239-1245
[DOI] 10.1007/s00268-016-3861-y.
[PMID] 28050668.
2017
Characterization of hypoalbuminemia following temporary abdominal closure.
The journal of trauma and acute care surgery.
83(4):650-656
[DOI] 10.1097/TA.0000000000001553.
[PMID] 28837537.
2017
Clonidine reduces norepinephrine and improves bone marrow function in a rodent model of lung contusion, hemorrhagic shock, and chronic stress.
Surgery.
161(3):795-802
[DOI] 10.1016/j.surg.2016.08.043.
[PMID] 27742030.
2017
Clonidine restores vascular endothelial growth factor expression and improves tissue repair following severe trauma
The American Journal of Surgery.
214(4):610-615
[DOI] 10.1016/j.amjsurg.2017.06.019.
[PMID] 28666582.
2017
Computed tomography evidence of fluid in the hernia sac predicts surgical site infection following mesh repair of acutely incarcerated ventral and groin hernias.
The journal of trauma and acute care surgery.
83(1):170-174
[DOI] 10.1097/TA.0000000000001503.
[PMID] 28426559.
2017
Daily propranolol administration reduces persistent injury-associated anemia after severe trauma and chronic stress.
The journal of trauma and acute care surgery.
82(4):714-721
[DOI] 10.1097/TA.0000000000001374.
[PMID] 28099381.
2017
Early bronchoalveolar lavage for intubated trauma patients with TBI or chest trauma.
Journal of critical care.
39:78-82
[DOI] 10.1016/j.jcrc.2017.02.010.
[PMID] 28231518.
2017
Effects of trauma, hemorrhagic shock, and chronic stress on lung vascular endothelial growth factor
Journal of Surgical Research.
210:15-21
[DOI] 10.1016/j.jss.2016.10.023.
[PMID] 28457321.
2017
Emergent laparotomy and temporary abdominal closure for the cirrhotic patient.
The Journal of surgical research.
210:108-114
[DOI] 10.1016/j.jss.2016.11.013.
[PMID] 28457316.
2017
Human Myeloid-derived Suppressor Cells are Associated With Chronic Immune Suppression After Severe Sepsis/Septic Shock.
Annals of surgery.
265(4):827-834
[DOI] 10.1097/SLA.0000000000001783.
[PMID] 27163951.
2017
Improved outcomes following implementation of an acute gastrointestinal bleeding multidisciplinary protocol.
The journal of trauma and acute care surgery.
83(1):41-46
[DOI] 10.1097/TA.0000000000001295.
[PMID] 27779592.
2017
Microbial recognition and danger signals in sepsis and trauma.
Biochimica et biophysica acta. Molecular basis of disease.
1863(10 Pt B):2564-2573
[DOI] 10.1016/j.bbadis.2017.01.013.
[PMID] 28115287.
2017
Murine Models of Sepsis and Trauma: Can We Bridge the Gap?
ILAR journal.
58(1):90-105
[DOI] 10.1093/ilar/ilx007.
[PMID] 28444204.
2017
Neural network prediction of severe lower intestinal bleeding and the need for surgical intervention.
The Journal of surgical research.
212:42-47
[DOI] 10.1016/j.jss.2016.12.032.
[PMID] 28550920.
2017
Percutaneous cholecystostomy: prognostic factors and comparison to cholecystectomy.
Surgical endoscopy.
31(11):4568-4575
[DOI] 10.1007/s00464-017-5517-x.
[PMID] 28409378.
2017
Persistent injury-associated anemia: the role of the bone marrow microenvironment
Journal of Surgical Research.
214:240-246
[DOI] 10.1016/j.jss.2017.03.018.
[PMID] 28624051.
2017
Predicting appendiceal tumors among patients with appendicitis.
The journal of trauma and acute care surgery.
82(4):771-775
[DOI] 10.1097/TA.0000000000001378.
[PMID] 28099380.
2017
Routine surveillance cholangiography after percutaneous cholecystostomy delays drain removal and cholecystectomy.
The journal of trauma and acute care surgery.
82(2):351-355
[DOI] 10.1097/TA.0000000000001315.
[PMID] 27893641.
2017
Sepsis and Critical Illness Research Center investigators: protocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients.
BMJ open.
7(7)
[DOI] 10.1136/bmjopen-2016-015136.
[PMID] 28765125.
2017
Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome.
Critical care medicine.
45(2):253-262
[DOI] 10.1097/CCM.0000000000002074.
[PMID] 27632674.
2017
Severe trauma and chronic stress activates extramedullary erythropoiesis.
The journal of trauma and acute care surgery.
83(1):144-150
[DOI] 10.1097/TA.0000000000001537.
[PMID] 28452894.
2017
Temporary abdominal closure for trauma and intra-abdominal sepsis: Different patients, different outcomes.
The journal of trauma and acute care surgery.
82(2):345-350
[DOI] 10.1097/TA.0000000000001283.
[PMID] 27787442.
2017
The effects of red cell transfusion donor age on nosocomial infection among trauma patients
The American Journal of Surgery.
214(4):672-676
[DOI] 10.1016/j.amjsurg.2017.07.004.
[PMID] 28720216.
2017
The Novel Use of Resuscitative Endovascular Balloon Occlusion of the Aorta to Explore a Retroperitoneal Hematoma in a Hemodynamically Unstable Patient.
The American surgeon.
83(4):337-340
[PMID] 28424126.
2016
Characterization of erythropoietin and hepcidin in the regulation of persistent injury-associated anemia.
The journal of trauma and acute care surgery.
81(4):705-12
[DOI] 10.1097/TA.0000000000001163.
[PMID] 27398985.
2016
Intubated Trauma Patients Receiving Prolonged Antibiotics for Pneumonia despite Negative Cultures: Predictors and Outcomes.
Surgical infections.
17(6):766-772
[PMID] 27635693.
2016
Mesenchymal stem cells enhance lung recovery after injury, shock, and chronic stress
Surgery.
159(5):1430-1435
[DOI] 10.1016/j.surg.2015.12.006.
[PMID] 26830071.
2016
Novel use of a Sengstaken–Blakemore tube during a neck exploration of a carotid injury: A case report
Injury.
47(9):2048-2050
[DOI] 10.1016/j.injury.2016.03.008.
2016
Patterns of gene expression among murine models of hemorrhagic shock/trauma and sepsis.
Physiological genomics.
48(2):135-44
[DOI] 10.1152/physiolgenomics.00072.2015.
[PMID] 26578697.
2016
β-Blockade use for Traumatic Injuries and Immunomodulation: A Review of Proposed Mechanisms and Clinical Evidence.
Shock (Augusta, Ga.).
46(4):341-51
[DOI] 10.1097/SHK.0000000000000636.
[PMID] 27172161.
2015
A Detailed Characterization of the Dysfunctional Immunity and Abnormal Myelopoiesis Induced by Severe Shock and Trauma in the Aged.
Journal of immunology (Baltimore, Md. : 1950).
195(5):2396-407
[DOI] 10.4049/jimmunol.1500984.
[PMID] 26246141.
2015
A protocol for the management of adhesive small bowel obstruction.
The journal of trauma and acute care surgery.
78(1):13-9; discussion 19
[DOI] 10.1097/TA.0000000000000491.
[PMID] 25539198.
2015
Analysis of Hypoxemia in Early Ventilator-Associated Pneumonia Secondary to Haemophilus in Trauma Patients.
Surgical infections.
16(3):293-7
[DOI] 10.1089/sur.2013.156.
[PMID] 25894664.
2015
Can mesenchymal stem cells reverse chronic stress-induced impairment of lung healing following traumatic injury?
The journal of trauma and acute care surgery.
78(4):767-72
[DOI] 10.1097/TA.0000000000000592.
[PMID] 25807405.
2015
Chronic restraint stress after injury and shock is associated with persistent anemia despite prolonged elevation in erythropoietin levels.
The journal of trauma and acute care surgery.
79(1):91-6; discussion 96
[DOI] 10.1097/TA.0000000000000686.
[PMID] 26091320.
2015
Daily propranolol prevents prolonged mobilization of hematopoietic progenitor cells in a rat model of lung contusion, hemorrhagic shock, and chronic stress.
Surgery.
158(3):595-601
[DOI] 10.1016/j.surg.2015.06.031.
[PMID] 26209570.
2015
Human Myeloid Derived Suppressor Cells Induce Immune Suppression After Severe Sepsis
Shock.
43(6, 1)
2015
Mesenchymal stem cells increase T-regulatory cells and improve healing following trauma and hemorrhagic shock.
The journal of trauma and acute care surgery.
79(1):48-52; discussion 52
[DOI] 10.1097/TA.0000000000000681.
[PMID] 26091313.
2015
Mesenchymal stem cells reverse bone marrow dysfunction following injury and stress.
The journal of trauma and acute care surgery.
79(4):602-8
[DOI] 10.1097/TA.0000000000000823.
[PMID] 26402534.
2015
Sphingosine-1-Phospate/S1P Receptors Modulate Hematopoietic Progenitor Cell Mobilization Following Trauma/Hemorrhagic Shock
Shock.
43(6, 1)
2015
The future of murine sepsis and trauma research models.
Journal of leukocyte biology.
98(6):945-52
[DOI] 10.1189/jlb.5MR0315-127R.
[PMID] 26034205.
2015
The Monocyte That Wasn’t.
Critical care medicine.
43(7):1532-4
[DOI] 10.1097/CCM.0000000000001046.
[PMID] 26079230.
2014
A Comparison of the Leukocyte Genomic Responses To Sterile Or Infectious Inflammation
Shock.
41(2)
2014
Bacteremia and ventilator-associated pneumonia: a marker for contemporaneous extra-pulmonic infection.
Surgical infections.
15(2):77-83
[DOI] 10.1089/sur.2012.030.
[PMID] 24192306.
2014
Do all β-blockers attenuate the excess hematopoietic progenitor cell mobilization from the bone marrow following trauma/hemorrhagic shock?
The journal of trauma and acute care surgery.
76(4):970-5
[DOI] 10.1097/TA.0000000000000181.
[PMID] 24662859.
2014
Early propranolol administration to severely injured patients can improve bone marrow dysfunction.
The journal of trauma and acute care surgery.
77(1):54-60; discussion 59
[DOI] 10.1097/TA.0000000000000264.
[PMID] 24977755.
2014
Genomic Analysis of Individual Leukocyte Populations After Severe Trauma
Shock.
41(2)
2014
Is extended antibiotic prophylaxis necessary after penetrating trauma to the thoracolumbar spine with concomitant intraperitoneal injuries?
Surgical infections.
15(1):8-13
[DOI] 10.1089/sur.2012.139.
[PMID] 24116741.
2014
The Female Transcriptomic Response After Severe Trauma Is Different From That of Males
Shock.
41(2)
2014
The Lung Neutrophil Transcriptome After Trauma Influences the Worse Outcomes of the Old To Pneumonia
Critical Care Medicine.
42(12, S)
2013
Beta Blockade Protection of Bone Marrow Following Injury: A Critical Link between Heart Rate and Immunomodulation.
Journal of bone marrow research.
1
[PMID] 25621308.
2013
Distributed, limbic gray matter atrophy in patients after bacterial meningitis.
AJNR. American journal of neuroradiology.
34(6):1164-7
[DOI] 10.3174/ajnr.A3351.
[PMID] 23194831.
2013
Neurologic outcome of minimal head injury patients managed with or without a routine repeat head computed tomography.
The journal of trauma and acute care surgery.
75(2):273-8
[DOI] 10.1097/TA.0b013e3182905eb4.
[PMID] 23702628.
2013
Obesity does not increase morbidity and mortality after laparotomy for trauma.
The American surgeon.
79(3):247-52
[PMID] 23461948.
2013
The role of plasma granulocyte colony stimulating factor and bone marrow dysfunction after severe trauma.
Journal of the American College of Surgeons.
216(1):57-64
[DOI] 10.1016/j.jamcollsurg.2012.08.028.
[PMID] 23063381.
2013
Transfusion begets anemia: the effect of aged blood on hematopoiesis.
The journal of trauma and acute care surgery.
75(6):984-9
[DOI] 10.1097/TA.0b013e31829530c7.
[PMID] 24256670.
2012
Does selective beta-1 blockade provide bone marrow protection after trauma/hemorrhagic shock?
Surgery.
152(3):322-30
[DOI] 10.1016/j.surg.2012.06.016.
[PMID] 22938894.
2012
Is the sympathetic system involved in shock-induced gut and lung injury?
The journal of trauma and acute care surgery.
73(2):343-50; discussion 350
[DOI] 10.1097/TA.0b013e31825a785a.
[PMID] 22846938.
2012
The role and value of surgical critical care, an essential component of Acute Care Surgery, in the Affordable Care Act: a report from the Critical Care Committee and Board of Managers of the American Association for the Surgery of Trauma.
The journal of trauma and acute care surgery.
73(1):20-6
[DOI] 10.1097/TA.0b013e31825a78d5.
[PMID] 22743368.
2012
The temporal course of intracranial haemorrhage progression: how long is observation necessary?
Injury.
43(12):2122-5
[DOI] 10.1016/j.injury.2012.04.013.
[PMID] 22658418.
2012
Vagal nerve stimulation modulates gut injury and lung permeability in trauma-hemorrhagic shock.
The journal of trauma and acute care surgery.
73(2):338-42; discussion 342
[DOI] 10.1097/TA.0b013e31825debd3.
[PMID] 22846937.
2011
Beta-blockade prevents hematopoietic progenitor cell suppression after hemorrhagic shock.
Surgical infections.
12(4):273-8
[DOI] 10.1089/sur.2010.043.
[PMID] 21790478.
2011
Does beta blockade postinjury prevent bone marrow suppression?
The Journal of trauma.
70(5):1043-9; discussion 1049
[DOI] 10.1097/TA.0b013e3182169326.
[PMID] 21610422.
2011
Feasibility of flat panel angiographic CT after intravenous contrast agent application in the postoperative evaluation of patients with clipped aneurysms.
AJNR. American journal of neuroradiology.
32(10):1956-62
[DOI] 10.3174/ajnr.A2611.
[PMID] 21852377.
2011
Impact of enhanced mobilization of bone marrow derived cells to site of injury.
The Journal of trauma.
71(2):283-9; discussion 289
[DOI] 10.1097/TA.0b013e318222f380.
[PMID] 21825928.
2011
β-blockade protection of bone marrow following trauma: the role of G-CSF.
The Journal of surgical research.
170(2):325-31
[DOI] 10.1016/j.jss.2011.03.059.
[PMID] 21571320.
2010
Dose-response relationship between norepinephrine and erythropoiesis: evidence for a critical threshold.
The Journal of surgical research.
163(2):e85-90
[DOI] 10.1016/j.jss.2010.03.051.
[PMID] 20605580.
2010
Gender differences in glucose variability after severe trauma.
The American surgeon.
76(8):896-902
[PMID] 20726425.
2010
Hematopoietic progenitor cell mobilization is mediated through beta-2 and beta-3 receptors after injury.
The Journal of trauma.
69(2):338-43
[DOI] 10.1097/TA.0b013e3181e5d35e.
[PMID] 20699742.
2009
Mobilization of bone marrow cells to the site of injury is necessary for wound healing.
The Journal of trauma.
67(2):315-21; discussion 321
[DOI] 10.1097/TA.0b013e3181a5c9c7.
[PMID] 19667884.
2008
Haemorrhagic shock therapy.
Expert opinion on pharmacotherapy.
9(6):901-11
[DOI] 10.1517/14656566.9.6.901.
[PMID] 18377334.
2008
Necrotizing fasciitis and sepsis caused by Aeromonas hydrophila after crush injury of the lower extremity.
Surgical infections.
9(4):459-67
[DOI] 10.1089/sur.2007.028.
[PMID] 18687029.
2008
Routine use of bilateral skeletonized internal thoracic artery grafting: long-term results.
Circulation.
118(7):705-12
[DOI] 10.1161/CIRCULATIONAHA.107.756676.
[PMID] 18663087.
2008
The impact of obesity on the outcome of emergency intubation in trauma patients.
The Journal of trauma.
65(2):396-400
[DOI] 10.1097/TA.0b013e31817f97fd.
[PMID] 18695478.
2007
Hematopoietic progenitor cells mobilize to the site of injury after trauma and hemorrhagic shock in rats.
The Journal of trauma.
63(3):596-600; discussion 600
[PMID] 18073606.
2007
Sex hormones affect bone marrow dysfunction after trauma and hemorrhagic shock.
Critical care medicine.
35(3):864-9
[PMID] 17255869.
2007
Use of aerosolized aminoglycosides in the treatment of Gram-negative ventilator-associated pneumonia.
Surgical infections.
8(3):349-57
[PMID] 17635058.
2006
A prospective evaluation of the value of repeat cranial computed tomography in patients with minimal head injury and an intracranial bleed.
The Journal of trauma.
61(4):862-7
[PMID] 17033552.
2006
Bone marrow failure in male rats following trauma/hemorrhagic shock (T/HS) is mediated by mesenteric lymph and modulated by castration.
Shock (Augusta, Ga.).
25(1):12-6
[PMID] 16369180.
2006
Effects of mycophenolic acid on inosine monophosphate dehydrogenase I and II mRNA expression in white blood cells and various tissues in sheep.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine.
53(4):163-9
[PMID] 16629948.
2005
Civilian craniocerebral gunshot wounds: an update in predicting outcomes.
The American surgeon.
71(12):1009-14
[PMID] 16447469.
2005
Recombinant activated factor VIIa and hemostasis in critical care: a focus on trauma.
Critical care (London, England).
9 Suppl 5(Suppl 5):S37-42
[PMID] 16221318.
2005
The impact of a hypercatecholamine state on erythropoiesis following severe injury and the role of IL-6.
The Journal of trauma.
59(4):884-9; discussion 889
[PMID] 16374277.
2004
Adrenergic modulation of erythropoiesis following severe injury is mediated through bone marrow stroma.
Surgical infections.
5(4):385-93
[PMID] 15744130.
2004
Small volume albumin administration protects against hemorrhagic shock-induced bone marrow dysfunction.
The Journal of trauma.
56(2):279-83
[PMID] 14960968.
2004
Value of repeat cranial computed axial tomography scanning in patients with minimal head injury.
American journal of surgery.
187(3):338-42
[PMID] 15006561.
2003
[Sudden onset of unilateral right-sided symptoms. Unilateral venous infarct of the left thalamus in thrombosis of the internal cerebral veins].
Der Radiologe.
43(1):77-80
[PMID] 12645504.
2003
Angiographic embolization for liver injuries: low mortality, high morbidity.
The Journal of trauma.
55(6):1077-81; discussion 1081
[PMID] 14676654.
2003
Management of trauma to the male external genitalia: the usefulness of American Association for the Surgery of Trauma organ injury scales.
The Journal of urology.
170(6 Pt 1):2311-5
[PMID] 14634403.
2002
Delayed differentiation of HL-60 cells following exposure to hypoxia.
The Journal of surgical research.
108(2):243-9
[PMID] 12505048.
2001
Src homology 2-containing inositol 5-phosphatase 1 binds to the multifunctional docking site of c-Met and potentiates hepatocyte growth factor-induced branching tubulogenesis.
The Journal of biological chemistry.
276(5):3017-23
[PMID] 11069926.
2001
The role of dead space ventilation in predicting outcome of successful weaning from mechanical ventilation.
The Journal of trauma.
51(5):843-8
[PMID] 11706329.
1998
Effect of hypoxia on the hematopoietic and immune modulator preprotachykinin-I.
Archives of surgery (Chicago, Ill. : 1960).
133(12):1328-34
[PMID] 9865651.
1997
Differential effects of acute hypoxia and endotoxin on the secretion and expression of bone marrow interleukin-1 and interleukin-6.
Shock (Augusta, Ga.).
7(5):324-31
[PMID] 9165666.
Grants
May 2021
– Jul 2022
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of Intravenous FDY-5301 for the Prevention and Treatment of ICU Acquired Weakness in Major Trauma Patients
Role: Principal Investigator
Funding: MEDPACE
via FARADAY PHARMACEUTICALS
May 2021
ACTIVE
Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis Pathobiology
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Aug 2018
– Jul 2023
Chronic Stress and Anemia Recovery following Major Trauma
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Jun 2018
– May 2020
PICS: A New Horizon for Surgical Critical Care
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Sep 2017
– Sep 2020
The Pathogenesis of Post-Traumatic Pulmonary Embolism: A Prospective Multi-Center INvestigation by the CLOTT Study Group (CLOTT)
Role: Principal Investigator
Funding: COALITION FOR NATL TRAUMA RES
via US ARMY MED RES AND DEVELOPMENT COMMAND
Jun 2017
– May 2018
PICS: A New Horizon for Surgical Critical Care
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Apr 2015
– Jan 2021
Hematopoietic Stem Cell Dysfunction in the Elderly after Severe Injury
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Jan 2014
– Jan 2017
FCPA Start up funds
Role: Principal Investigator
Funding: FL CLINICAL PRACTICE ASSO
Jan 2014
– Jul 2018
Anemia and the Chronic Hyperadrenergic State following Major Trauma
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Education
Fellowship – Surgical Critical Care
2000
·
University of North Carolina
Residency – Surgery
1999
·
The University of Medicine and Dentistry of New Jersey
Medical Degree
1993
·
The University of Medicine and Dentistry of New Jersey
Bachelor's Degree
1989
·
Rutgers University
Associate's Degree
1987
·
Felician College
Contact Details
Phones:
- Business:
- (352) 273-5670
Emails:
- Business:
- mohr@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100108
GAINESVILLE FL 32610 - Business Street:
-
PO Box 100108
GAINESVILLE FL 32610