Benjamin N Jacobs

Benjamin N Jacobs, MD

Assistant Professor

Business Phone: (352) 273-9169

About Benjamin N Jacobs

Hi, my name is Benjamin Jacobs, MD, and I am an assistant professor in the University of Florida Division of Vascular Surgery and Endovascular Therapy. I am board certified in surgery by the American Board of Surgery and am a member of the American Venous Forum, the American College of Surgeons, the Association for Academic Surgery and the Society for Vascular Surgery.

I earned my bachelor’s degree in history with a minor in religious studies from Eastern Michigan University, and my master’s degree in biomedical sciences and medical degree from the University of Toledo. I completed my internship and general surgery residency at the University of Michigan Health System, followed by a vascular surgery fellowship at Dartmouth Hitchcock Medical Center. During my training, I received multiple honors and awards, including the Bryant-Arnold Teaching Award from the Frederick A. Coller Surgical Society and the Greenfield Research Award. While completing my general surgery residency, I spent two years of academic development time in a basic science lab studying deep vein thrombosis.

My interest in a career in vascular surgery began in medical school. I felt a connection to vascular patients and a call to care for patients from diverse backgrounds dealing with such a complex and difficult disease. The challenge of treating a disease with such a detrimental effect on quality of life and happiness is what drives me every day.

I treat the full spectrum of vascular disease, including aneurysm, cerebrovascular disease (open and minimally invasive techniques), peripheral arterial and venous disease. However, I think of myself primarily as a limb salvage surgeon – I treat wounds on the legs due to arterial or venous pathology. Conditions I treat include peripheral vascular disease, critical limb ischemia, diabetic foot wounds, venous stasis ulcers and post-thrombotic syndrome.

I specialize in complex “minimally invasive” (endovascular) therapies for arterial and venous peripheral disease. I have a unique practice in the reopening of occluded venous stents that may have been unable to be reopened elsewhere. I am the lead physician for our vein practice, treating varicose veins, lower extremity swelling and pain, and venous insuffiency and venous stasis with the latest technology, including radiofrequency ablation. I have an entire clinic dedicated to venous disease and vein patients once a week.

My clinical and research interests include venous thromboembolic disease, acute deep vein thrombosis, pulmonary embolisms, pathophysiology of varicose veins and nanoparticle-directed venous therapy. I am the site PI for Promise II and Promise III Clinical Trials for Deep Vein Arterialization for Limb Salvage and “no-option” Critical Limb Ischemia. This trial may offer hope to patients with peripheral vascular disease facing amputation who may have been told nothing could be done to revascularize the limb.

I want my current and future patients to know I try to be as clear, understandable and human as possible. I remember very well what it was like to not know anything about vascular disease and to hear words like “stent” and “endovascular” and think, “what the heck is this guy talking about?” While these diseases and operations may be commonplace to providers, it’s the first time it’s happening to our patients and it’s important for us to remember that.

I was born in the state of Michigan and am a second-generation vascular surgeon. When I’m not practicing medicine, I enjoy reading science fiction novels.


Bryant-Arnold Teaching Award
2017 · Frederick Coller Society

Teaching Profile

Courses Taught
BMS6634 GI and Hepatology
BMS6633 The Cv System

Board Certifications

  • Surgery
    American Board of Surgery

Clinical Profile

  • Vascular Surgery
Areas of Interest
  • Abdominal aortic aneurysm
  • Abdominal aortic aneurysm repair – open
  • Aortic aneurysm repair – endovascular
  • Arterial insufficiency
  • Cerebrovascular occlusive disease
  • Deep vein thrombosis
  • Heart and vascular services
  • Mesenteric artery ischemia
  • Mesenteric venous thrombosis
  • Peripheral arterial occlusive disease
  • Peripheral artery bypass – leg
  • Peripheral artery disease
  • Peripheral artery disease – legs
  • Pulmonary embolus
  • Renal vein thrombosis
  • Thoracic aortic aneurysm (TAA)
  • Varicose veins
  • Venous Disease
  • Venous insufficiency

Research Profile

Areas of Interest
  • Abdominal aortic aneurysm
  • Acute deep vein thrombosis
  • Arterial pathologies
  • Cerebrovascular disease
  • Nanoparticle-directed venous therapy
  • Peripheral arterial disease
  • Pulmonary embolisms
  • Vascular disease
  • Venous pathologies
  • Venous thromboembolic disease


Comparative outcomes of open mesenteric bypass after a failed endovascular or open mesenteric revascularization for chronic mesenteric ischemia.
Journal of vascular surgery. [DOI] 10.1016/j.jvs.2024.03.028. [PMID] 38552885.
Factors associated with lack of clinical improvement after vein ablation in the vascular quality initiative.
Journal of vascular surgery. Venous and lymphatic disorders. [DOI] 10.1016/j.jvsv.2024.101884. [PMID] 38552954.
Laser assisted trans-endograft coil embolization of a type II endoleak.
Journal of vascular surgery cases and innovative techniques. 10(3) [DOI] 10.1016/j.jvscit.2024.101442. [PMID] 38510092.
Size thresholds for repair of abdominal aortic aneurysms warrant reconsideration.
Journal of vascular surgery. 79(5):1069-1078.e8 [DOI] 10.1016/j.jvs.2024.01.017. [PMID] 38262565.
The Contemporary Impact of Body Mass Index on Open Aortic Aneurysm Repair.
Journal of vascular surgery. [DOI] 10.1016/j.jvs.2023.01.019. [PMID] 36682598.
Ventriculo-inferior-venacaval shunt salvage via endovascular surgery.
British journal of neurosurgery. 1-3 [DOI] 10.1080/02688697.2023.2233619. [PMID] 37424104.
Outcomes of endovascular abdominal aortic aneurysm repair conversion in octogenarians treated at a high-volume aorta center.
Journal of vascular surgery. 76(5):1270-1279 [DOI] 10.1016/j.jvs.2022.04.033. [PMID] 35667603.
Effect of Mentoring on Match Rank of Integrated Vascular Surgery Residents.
Annals of vascular surgery. 64:285-291 [DOI] 10.1016/j.avsg.2019.03.033. [PMID] 31200040.
Ectonucleotidase tri(di)phosphohydrolase-1 (ENTPD-1) disrupts inflammasome/interleukin 1β-driven venous thrombosis.
The Journal of clinical investigation. 129(7):2872-2877 [DOI] 10.1172/JCI124804. [PMID] 30990798.
Empirical systemic anticoagulation is associated with decreased venous thromboembolism in critically ill influenza A H1N1 acute respiratory distress syndrome patients.
Journal of vascular surgery. Venous and lymphatic disorders. 7(3):317-324 [DOI] 10.1016/j.jvsv.2018.08.010. [PMID] 30477976.
Pilot Study to Evaluate the Safety, Feasibility, and Financial Implications of a Postoperative Telemedicine Program.
Annals of surgery. 268(4):700-707 [DOI] 10.1097/SLA.0000000000002931. [PMID] 30095477.
Macrophage-Mediated Inflammation in Normal and Diabetic Wound Healing.
Journal of immunology (Baltimore, Md. : 1950). 199(1):17-24 [DOI] 10.4049/jimmunol.1700223. [PMID] 28630109.
Pathophysiology of varicose veins.
Journal of vascular surgery. Venous and lymphatic disorders. 5(3):460-467 [DOI] 10.1016/j.jvsv.2016.12.014. [PMID] 28411716.
Unfractionated heparin versus low-molecular-weight heparin for venous thromboembolism prophylaxis in trauma.
The journal of trauma and acute care surgery. 83(1):151-158 [DOI] 10.1097/TA.0000000000001494. [PMID] 28426561.


Nov 2022 ACTIVE
Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
Role: Principal Investigator
Funding: NAMSA via LIMFLOW
Jan 2022 – Dec 2023
Percutaneous Deep Vein arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
Role: Principal Investigator
Funding: LIMFLOW


Residency in Vascular Surgery
2019-2021 · Dartmouth-Hitchcock Health Care System
Residency in Surgery
2012-2019 · University of Michigan
Medical Degree
2008-2012 · University of Toledo
Bachelor of Arts in History
1999-2005 · Eastern Michigan University

Contact Details

(352) 273-9169
Business Mailing:
PO Box 100128