Sergio Duarte

Sergio Duarte, PhD

Research Assistant Professor

Department: MD-SURGERY-GEN-TRANSPLANT
Business Phone: (352) 594-4111
Business Email: s.duarte@ufl.edu

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-1036-6850

Publications

2024
Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy.
Hepatology communications. 8(2) [DOI] 10.1097/HC9.0000000000000370. [PMID] 38285890.
2023
Current Trends in Surgical Management of Hepatocellular Carcinoma.
Cancers. 15(22) [DOI] 10.3390/cancers15225378. [PMID] 38001637.
2023
Effects of Clinical and Tumor Characteristics on Survival in Patients with Hepatocellular Carcinoma with Bone Metastasis.
Journal of hepatocellular carcinoma. 10:1129-1141 [DOI] 10.2147/JHC.S417273. [PMID] 37489126.
2023
Loss of CEACAM1 in endothelial cells causes hepatic fibrosis.
Metabolism: clinical and experimental. 144 [DOI] 10.1016/j.metabol.2023.155562. [PMID] 37088122.
2023
Low vs Standard-Dose Indocyanine Green in the Identification of Biliary Anatomy Using Near-Infrared Fluorescence Imaging: A Multicenter Randomized Controlled Trial.
Journal of the American College of Surgeons. 236(4):711-717 [DOI] 10.1097/XCS.0000000000000553. [PMID] 36728303.
2023
Mechanisms of drug resistance in HCC.
Hepatology (Baltimore, Md.). 79(4):926-940 [DOI] 10.1097/HEP.0000000000000237.
2023
Personalized Tacrolimus Dosing After Liver Transplantation: A Randomized Clinical Trial.
medRxiv : the preprint server for health sciences. [DOI] 10.1101/2023.05.26.23290604. [PMID] 37397983.
2023
Secondary Cold Ischemia After Normothermic Machine Perfusion: A Drawback to Centralized Organ Perfusion Centers?
Transplantation. 107(6):1237-1239 [DOI] 10.1097/TP.0000000000004569. [PMID] 36922377.
2023
Soluble DNA concentration in the perfusate is a predictor of post-transplant renal function in hypothermic perfused kidney allografts
MedrXiv. [DOI] https://doi.org/10.1101/2023.05.16.23289983.
2023
The Future Is Now: OrganEx Technology and Its Implications for Transplant Medicine.
Transplantation. 107(4):799-800 [DOI] 10.1097/TP.0000000000004496. [PMID] 37001552.
2022
Characterization of hepatic inflammatory changes in a C57BL/6J mouse model of alpha1-antitrypsin deficiency.
American journal of physiology. Gastrointestinal and liver physiology. 323(6):G594-G608 [DOI] 10.1152/ajpgi.00207.2022. [PMID] 36256438.
2022
High levels of donor-derived cell-free DNA in a case of graft-versus-host-disease following liver transplantation
American Journal of Transplantation. 22(3):973-976 [DOI] 10.1111/ajt.16894.
2022
No Salvation Without Regeneration.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 28(5):749-750 [DOI] 10.1002/lt.26413. [PMID] 35090090.
2020
Jagged1-mediated myeloid Notch1 signaling activates HSF1/Snail and controls NLRP3 inflammasome activation in liver inflammatory injury.
Cellular & molecular immunology. 17(12):1245-1256 [DOI] 10.1038/s41423-019-0318-x. [PMID] 31673056.
2020
Tissue Inhibitor of Metalloproteinase 3 Deficiency Disrupts the Hepatocyte E-Cadherin/β-Catenin Complex and Induces Cell Death in Liver Ischemia/Reperfusion Injury.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 26(1):113-126 [DOI] 10.1002/lt.25667. [PMID] 31642174.
2019
Epithelial Membrane Protein-2 (EMP2) Antibody Blockade Reduces Corneal Neovascularization in an In Vivo Model.
Investigative ophthalmology & visual science. 60(1):245-254 [DOI] 10.1167/iovs.18-24345. [PMID] 30646013.
2019
Overproduction of Tenascin-C Driven by Lipid Accumulation in the Liver Aggravates Hepatic Ischemia/Reperfusion Injury in Steatotic Mice.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 25(2):288-301 [DOI] 10.1002/lt.25365. [PMID] 30358115.
2019
Quantitative Measure of Intestinal Permeability Using Blue Food Coloring.
The Journal of surgical research. 233:20-25 [DOI] 10.1016/j.jss.2018.07.005. [PMID] 30502249.
2018
Adeno-Associated Virus-Mediated Gene Transfer of Tissue Inhibitor of Metalloproteinases-1 Impairs Neutrophil Extracellular Trap Formation and Ameliorates Hepatic Ischemia and Reperfusion Injury.
The American journal of pathology. 188(8):1820-1832 [DOI] 10.1016/j.ajpath.2018.05.002. [PMID] 29870740.
2018
Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma.
Journal of Cancer. 9(1):1-12 [DOI] 10.7150/jca.21747. [PMID] 29290764.
2018
Human hepatocyte transplantation corrects the inherited metabolic liver disorder arginase deficiency in mice.
Molecular genetics and metabolism. 124(2):114-123 [DOI] 10.1016/j.ymgme.2018.04.005. [PMID] 29724658.
2018
Noninvasive Imaging of Drug-Induced Liver Injury with 18F-DFA PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 59(8):1308-1315 [DOI] 10.2967/jnumed.117.206961. [PMID] 29496991.
2015
Matrix Metalloproteinase-2 (MMP-2) Gene Deletion Enhances MMP-9 Activity, Impairs PARP-1 Degradation, and Exacerbates Hepatic Ischemia and Reperfusion Injury in Mice.
PloS one. 10(9) [DOI] 10.1371/journal.pone.0137642. [PMID] 26355684.
2015
Matrix metalloproteinases in liver injury, repair and fibrosis.
Matrix biology : journal of the International Society for Matrix Biology. 44-46:147-56 [DOI] 10.1016/j.matbio.2015.01.004. [PMID] 25599939.
2014
Hepatic ischemia and reperfusion injury in the absence of myeloid cell-derived COX-2 in mice.
PloS one. 9(5) [DOI] 10.1371/journal.pone.0096913. [PMID] 24819536.
2014
MMP-9 deficiency shelters endothelial PECAM-1 expression and enhances regeneration of steatotic livers after ischemia and reperfusion injury.
Journal of hepatology. 60(5):1032-9 [DOI] 10.1016/j.jhep.2013.12.022. [PMID] 24412604.
2012
Fibronectin-α4β1 interactions in hepatic cold ischemia and reperfusion injury: regulation of MMP-9 and MT1-MMP via the p38 MAPK pathway.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12(10):2689-99 [DOI] 10.1111/j.1600-6143.2012.04161.x. [PMID] 22812390.
2012
Regulated hepatic reperfusion mitigates ischemia-reperfusion injury and improves survival after prolonged liver warm ischemia: a pilot study on a novel concept of organ resuscitation in a large animal model.
Journal of the American College of Surgeons. 214(4):505-15; discussion 515 [DOI] 10.1016/j.jamcollsurg.2011.12.010. [PMID] 22321520.
2012
TIMP-1 deficiency leads to lethal partial hepatic ischemia and reperfusion injury.
Hepatology (Baltimore, Md.). 56(3):1074-85 [DOI] 10.1002/hep.25710. [PMID] 22407827.
2011
Tenascin-C: a novel mediator of hepatic ischemia and reperfusion injury.
Hepatology (Baltimore, Md.). 54(6):2125-36 [DOI] 10.1002/hep.24639. [PMID] 21898491.
2009
Cytoprotective effects of a cyclic RGD peptide in steatotic liver cold ischemia and reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9(10):2240-50 [DOI] 10.1111/j.1600-6143.2009.02759.x. [PMID] 19681824.
2009
Inducible nitric oxide synthase deficiency impairs matrix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic ischemia/reperfusion injury.
The American journal of pathology. 174(6):2265-77 [DOI] 10.2353/ajpath.2009.080872. [PMID] 19443702.
2008
Cyclooxygenase-2 deficiency enhances Th2 immune responses and impairs neutrophil recruitment in hepatic ischemia/reperfusion injury.
Journal of immunology (Baltimore, Md. : 1950). 180(3):1843-53 [PMID] 18209082.

Grants

Dec 2024 ACTIVE
Targeted RNA-Lipid Particle Aggregates in Pediatric Oncology: A Novel Therapeutic Strategy for Fibrolamellar Hepatocellular Carcinoma
Role: Other
Funding: HYUNDAI HOPE ON WHEELS
Apr 2022 ACTIVE
Directing Tryptophan Immunometabolism to Ameliorate Liver Ischemic-Reperfusion Injury
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDDK
Sep 2019 – Nov 2023
Diversity Supplement: Novel Pathways in the Pathogenesis and Pathophysiology of NAFLD in Hispanics
Role: Principal Investigator
Funding: OHIO UNIV via NATL INST OF HLTH NIMHD

Contact Details

Phones:
Business:
(352) 594-4111
Emails:
Business:
s.duarte@ufl.edu
Addresses:
Business Mailing:
PO Box 100118
GAINESVILLE FL 32610
Business Street:
1600 SW Archer Rd, Rm 6142
GAINESVILLE FL 32610