Letitia E Bible, M.D.
Assistant Professor
About Letitia E Bible
As an assistant professor and surgeon in the University of Florida Division of Acute Care Surgery, I care for patients who are traumatically injured and critically ill. The opportunity to care for critically injured people is incredibly rewarding.
I earned my bachelor’s degree from Florida State University and medical degree from the University of Miami Miller School of Medicine. I pursued a residency at Rutgers New Jersey Medical School in Newark, serving as administrative chief resident in my final year. Then, I completed a fellowship in surgical critical care and acute care surgery at the University of Pittsburgh School of Medicine.
I am board certified in both general surgery and critical care by the American Board of Surgery. I have contributed to numerous manuscripts, presentations and research, with my interests involving trauma care, bone marrow dysfunction and chronic stress. In addition to founding various committees that direct diversity, equity and inclusion initiatives, I have also served on peer review and violence prevention committees.
Accomplishments
Administrative Chief Resident
2016-2017
·
New Jersey Medical School, Rutgers University
Senior Surgical Resident
2014-2017
·
New Jersey Medical School, Rutgers University
Board Certifications
-
Critical CareAmerican Board of Surgery
-
General SurgeryAmerican Board of Surgery
-
Neurocritical CareABA
Clinical Profile
Specialties
- Emergency Medicine
Subspecialties
- Critical Care Medicine
Areas of Interest
- Traumatic Injury
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-5417-4028
Publications
2024
A rare case of spontaneous hemoperitoneum in a bone marrow transplant recipient on VV-ECMO.
The American journal of the medical sciences.
[DOI] 10.1016/j.amjms.2024.08.017.
[PMID] 39168408.
2024
A rat model of multicompartmental traumatic injury and hemorrhagic shock induces bone marrow dysfunction and profound anemia.
Animal models and experimental medicine.
7(3):367-376
[DOI] 10.1002/ame2.12447.
[PMID] 38860566.
2024
Acute Emergence of the Intestinal Pathobiome after Postinjury Pneumonia
Journal of Trauma and Acute Care Surgery.
[DOI] 10.1097/ta.0000000000004300.
2024
Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot.
JCI insight.
9(2)
[DOI] 10.1172/jci.insight.175785.
[PMID] 38100268.
2024
Comparing teaching with tactile guidance with video modeling with self-evaluative video feedback to train medical skills.
Journal of applied behavior analysis.
[DOI] 10.1002/jaba.1100.
[PMID] 39031000.
2024
Current updates in precision and personalized medicine in sepsis and trauma
Surgery.
176(2):541-543
[DOI] 10.1016/j.surg.2024.03.048.
2024
Gut mycobiome dysbiosis after sepsis and trauma.
Critical care (London, England).
28(1)
[DOI] 10.1186/s13054-023-04780-4.
[PMID] 38212826.
2024
Multicompartmental Trauma Induces Persistent Inflammation and Organ Injury.
The Journal of surgical research.
293:266-273
[DOI] 10.1016/j.jss.2023.08.033.
[PMID] 37804796.
2024
Persistence and Sexual Dimorphism of Gut Dysbiosis and Pathobiome after Sepsis and Trauma.
Annals of surgery.
280(3):491-503
[DOI] 10.1097/SLA.0000000000006385.
[PMID] 38864230.
2023
A narrative review of ergonomic problems, principles, and potential solutions in surgical operations
Surgery.
174(2):214-221
[DOI] 10.1016/j.surg.2023.04.003.
2023
Adverse Long-Term Outcomes and an Immune Suppressed Endotype in Sepsis Patients with Reduced Interferon-γELISpot: A Multicenter, Prospective Observational Study.
medRxiv : the preprint server for health sciences.
[DOI] 10.1101/2023.09.13.23295360.
[PMID] 37745385.
2023
Anemia Recovery After Lung Contusion, Hemorrhagic Shock, and Chronic Stress Is Gender-Specific in a Rat Model.
Surgical infections.
24(9):773-781
[DOI] 10.1089/sur.2023.154.
[PMID] 37903014.
2023
Anemia Recovery after Trauma: A Longitudinal Study.
Surgical infections.
24(1):39-45
[DOI] 10.1089/sur.2022.299.
[PMID] 36579920.
2023
EFFECTS OF TRAUMA PLASMA-DERIVED EXOSOMES ON HEMATOPOIETIC PROGENITOR CELLS.
Shock (Augusta, Ga.).
59(4):591-598
[DOI] 10.1097/SHK.0000000000002094.
[PMID] 36772985.
2023
Exosomal miRNA Following Severe Trauma: Role in Bone Marrow Dysfunction
Journal of Trauma and Acute Care Surgery.
[DOI] 10.1097/ta.0000000000004225.
2023
Failure to Rescue in Emergency General Surgery: Impact of Fragmentation of Care.
Annals of surgery.
277(1):93-100
[DOI] 10.1097/SLA.0000000000004628.
[PMID] 33214470.
2023
Multicompartmental traumatic injury induces sex-specific alterations in the gut microbiome.
The journal of trauma and acute care surgery.
95(1):30-38
[DOI] 10.1097/TA.0000000000003939.
[PMID] 36872509.
2023
NARROWING THE GAP: PRECLINICAL TRAUMA WITH POSTINJURY SEPSIS MODEL WITH INCREASED CLINICAL RELEVANCE.
Shock (Augusta, Ga.).
60(2):272-279
[DOI] 10.1097/SHK.0000000000002161.
[PMID] 37310788.
2023
Post-Traumatic Pneumonia Exacerbates Bone Marrow Erythropoietic Dysfunction
Journal of Trauma and Acute Care Surgery.
[DOI] 10.1097/ta.0000000000004157.
2023
Sex-specific intestinal dysbiosis persists after multicompartmental injury
Surgery.
174(6):1453-1462
[DOI] 10.1016/j.surg.2023.08.023.
2023
The Intestinal Microbiome after Traumatic Injury
Microorganisms.
11(8)
[DOI] 10.3390/microorganisms11081990.
[PMID] 37630549.
2022
After 9,000 laparotomies for blunt trauma, resuscitation is becoming more balanced and time to intervention shorter: Evidence in action.
The journal of trauma and acute care surgery.
93(3):307-315
[DOI] 10.1097/TA.0000000000003574.
[PMID] 35343923.
2022
Prospective validation of the Rib Injury Guidelines for traumatic rib fractures.
The journal of trauma and acute care surgery.
92(6):967-973
[DOI] 10.1097/TA.0000000000003535.
[PMID] 35125449.
2021
Delta Shock Index Predicts Outcomes in Pediatric Trauma Patients Regardless of Age
Journal of Surgical Research.
259:182-191
[DOI] 10.1016/j.jss.2020.10.026.
2021
Early Thromboprophylaxis in Operative Spinal Trauma Does Not Increase Risk of Bleeding Complications.
The Journal of surgical research.
258:119-124
[DOI] 10.1016/j.jss.2020.08.029.
[PMID] 33010556.
2021
Firearm-Related Injuries: A Single Center Experience
Journal of Surgical Research.
265:289-296
[DOI] 10.1016/j.jss.2021.03.058.
2021
Four-factor prothrombin complex concentrate in adjunct to whole blood in trauma-related hemorrhage: Does whole blood replace the need for factors?
The journal of trauma and acute care surgery.
91(1):34-39
[DOI] 10.1097/TA.0000000000003184.
[PMID] 33843830.
2021
Frail geriatric patients with acute calculous cholecystitis: Operative versus nonoperative management?
The journal of trauma and acute care surgery.
91(1):219-225
[DOI] 10.1097/TA.0000000000003115.
[PMID] 33605704.
2021
Managing acute uncomplicated appendicitis in frail geriatric patients: A second hit may be too much.
The journal of trauma and acute care surgery.
90(3):501-506
[DOI] 10.1097/TA.0000000000003028.
[PMID] 33617197.
2021
Never-frozen liquid plasma transfusion in civilian trauma: a nationwide propensity-matched analysis.
The journal of trauma and acute care surgery.
91(1):200-205
[DOI] 10.1097/TA.0000000000003116.
[PMID] 33605695.
2021
Open Versus Laparoscopic Repair of Traumatic Diaphragmatic Injury: A Nationwide Propensity-Matched Analysis.
The Journal of surgical research.
268:452-458
[DOI] 10.1016/j.jss.2021.07.022.
[PMID] 34416418.
2021
Open vs Endovascular Treatment of Traumatic Peripheral Arterial Injury: Propensity Matched Analysis.
Journal of the American College of Surgeons.
233(1):131-138.e4
[DOI] 10.1016/j.jamcollsurg.2021.02.021.
[PMID] 33771677.
2021
Platelet Transfusion After Traumatic Intracranial Hemorrhage in Patients on Antiplatelet Agents.
The Journal of surgical research.
257:239-245
[DOI] 10.1016/j.jss.2020.07.076.
[PMID] 32862051.
2021
Pre-Hospital Administration of Opioids in Trauma Patients: Is Dose Associated With Outcomes?
The Journal of surgical research.
268:634-642
[DOI] 10.1016/j.jss.2021.08.001.
[PMID] 34474212.
2021
Prospective Evaluation of Health Literacy and Its Impact on Outcomes in Emergency General Surgery.
The Journal of surgical research.
261:343-350
[DOI] 10.1016/j.jss.2020.12.047.
[PMID] 33486416.
2021
Racial and Ethnic Disparities in Frail Geriatric Trauma Patients.
World journal of surgery.
45(5):1330-1339
[DOI] 10.1007/s00268-020-05918-z.
[PMID] 33665725.
2021
Readmission With Major Abdominal Complications After Penetrating Abdominal Trauma.
The Journal of surgical research.
257:69-78
[DOI] 10.1016/j.jss.2020.07.060.
[PMID] 32818786.
2021
Regionalization of trauma care by operative experience: Does the volume of emergent laparotomy matter?
The journal of trauma and acute care surgery.
90(1):11-20
[DOI] 10.1097/TA.0000000000002911.
[PMID] 32925573.
2021
Resuscitative Endovascular Balloon Occlusion of the Aorta vs Pre-Peritoneal Packing in Patients with Pelvic Fracture.
Journal of the American College of Surgeons.
232(1):17-26.e2
[DOI] 10.1016/j.jamcollsurg.2020.08.763.
[PMID] 33022396.
2021
The Emergency Department Systolic Blood Pressure Relationship After Traumatic Brain Injury
Journal of Surgical Research.
257:493-500
[DOI] 10.1016/j.jss.2020.07.062.
2021
The survival benefit of low molecular weight heparin over unfractionated heparin in pediatric trauma patients.
Journal of pediatric surgery.
56(3):494-499
[DOI] 10.1016/j.jpedsurg.2020.07.021.
[PMID] 32883505.
2021
Traumatic brain injury induced temperature dysregulation: What is the role of β blockers?
The journal of trauma and acute care surgery.
90(1):177-184
[DOI] 10.1097/TA.0000000000002975.
[PMID] 33332783.
2021
Traumatic Femoral Artery Injuries and Predictors of Compartment Syndrome: A Nationwide Analysis.
The Journal of surgical research.
265:159-167
[DOI] 10.1016/j.jss.2021.03.039.
[PMID] 33940239.
2021
Trends in Geriatric Ground-Level Falls: Report from the National Trauma Data Bank
Journal of Surgical Research.
266:261-268
[DOI] 10.1016/j.jss.2021.02.047.
2021
Whole blood hemostatic resuscitation in pediatric trauma: A nationwide propensity-matched analysis.
The journal of trauma and acute care surgery.
91(4):573-578
[DOI] 10.1097/TA.0000000000003306.
[PMID] 34086658.
2020
Alcohol Use Disorder Is Bad for Broken Ribs: A Nationwide Analysis of 19,638 Patients With Rib Fractures.
The Journal of surgical research.
255:556-564
[DOI] 10.1016/j.jss.2020.05.053.
[PMID] 32640407.
2020
Angioembolization in intra-abdominal solid organ injury: Does delay in angioembolization affect outcomes?
The journal of trauma and acute care surgery.
89(4):723-729
[DOI] 10.1097/TA.0000000000002851.
[PMID] 33017133.
2020
Early Enteral Nutrition in Geriatric Burn Patients: Is There a Benefit?
Journal of burn care & research : official publication of the American Burn Association.
41(5):986-991
[DOI] 10.1093/jbcr/iraa109.
[PMID] 32598455.
2020
Impact of marijuana on venous thromboembolic events: Cannabinoids cause clots in trauma patients.
The journal of trauma and acute care surgery.
89(1):125-131
[DOI] 10.1097/TA.0000000000002667.
[PMID] 32209959.
2020
Nationwide analysis of cryopreserved packed red blood cell transfusion in civilian trauma.
The journal of trauma and acute care surgery.
89(5):861-866
[DOI] 10.1097/TA.0000000000002711.
[PMID] 32366762.
2020
Nationwide analysis of whole blood hemostatic resuscitation in civilian trauma.
The journal of trauma and acute care surgery.
89(2):329-335
[DOI] 10.1097/TA.0000000000002753.
[PMID] 32744830.
2020
The Evolution of Nonoperative Management of Abdominal Gunshot Wounds in the United States.
The Journal of surgical research.
253:224-231
[DOI] 10.1016/j.jss.2020.03.053.
[PMID] 32380348.
2020
The impact of non-neurological organ dysfunction on outcomes in severe isolated traumatic brain injury.
The journal of trauma and acute care surgery.
89(2):405-410
[DOI] 10.1097/TA.0000000000002771.
[PMID] 32744835.
2020
The neuroprotective effect of quetiapine in critically ill traumatic brain injury patients.
The journal of trauma and acute care surgery.
89(4):775-782
[DOI] 10.1097/TA.0000000000002866.
[PMID] 32649611.
2020
Treatment of blunt cerebrovascular injuries: Anticoagulants or antiplatelet agents?
The journal of trauma and acute care surgery.
89(1):74-79
[DOI] 10.1097/TA.0000000000002704.
[PMID] 32251264.
2017
Daily propranolol administration reduces persistent injury-associated anemia after severe trauma and chronic stress.
The journal of trauma and acute care surgery.
82(4):714-721
[DOI] 10.1097/TA.0000000000001374.
[PMID] 28099381.
2016
Mesenchymal stem cells enhance lung recovery after injury, shock, and chronic stress.
Surgery.
159(5):1430-5
[DOI] 10.1016/j.surg.2015.12.006.
[PMID] 26830071.
2015
Can mesenchymal stem cells reverse chronic stress-induced impairment of lung healing following traumatic injury?
The journal of trauma and acute care surgery.
78(4):767-72
[DOI] 10.1097/TA.0000000000000592.
[PMID] 25807405.
2015
Chronic restraint stress after injury and shock is associated with persistent anemia despite prolonged elevation in erythropoietin levels.
The journal of trauma and acute care surgery.
79(1):91-6; discussion 96
[DOI] 10.1097/TA.0000000000000686.
[PMID] 26091320.
2015
Daily propranolol prevents prolonged mobilization of hematopoietic progenitor cells in a rat model of lung contusion, hemorrhagic shock, and chronic stress.
Surgery.
158(3):595-601
[DOI] 10.1016/j.surg.2015.06.031.
[PMID] 26209570.
2015
Mesenchymal stem cells increase T-regulatory cells and improve healing following trauma and hemorrhagic shock.
The journal of trauma and acute care surgery.
79(1):48-52; discussion 52
[DOI] 10.1097/TA.0000000000000681.
[PMID] 26091313.
2015
Mesenchymal stem cells reverse bone marrow dysfunction following injury and stress.
The journal of trauma and acute care surgery.
79(4):602-8
[DOI] 10.1097/TA.0000000000000823.
[PMID] 26402534.
2015
Mesenchymal stem cells reverse trauma and hemorrhagic shock-induced bone marrow dysfunction.
The Journal of surgical research.
199(2):615-21
[DOI] 10.1016/j.jss.2015.06.023.
[PMID] 26193832.
2014
Early propranolol administration to severely injured patients can improve bone marrow dysfunction.
The journal of trauma and acute care surgery.
77(1):54-60; discussion 59
[DOI] 10.1097/TA.0000000000000264.
[PMID] 24977755.
Grants
Jul 2023
ACTIVE
Can the gut save the brain? An investigation of microbiome on the recovery from traumatic brain injury
Role: Principal Investigator
Funding: AMERICAN ASSOC FOR THE SURGERY OF TRAUMA
Education
Fellowship in Acute Care Surgery
2018-2019
·
University of Pittsburgh
Fellowship in Surgical Critical Care
2017-2018
·
University of Pittsburgh
Residency in Surgery
2010-2017
·
New Jersey Medical School, Rutgers University
Medical Degree
2006-2010
·
Miller School of Medicine, University of Miami
Bachelor's of Science
2002-2005
·
The Florida State University
Contact Details
Phones:
- Business:
- (352) 273-5670
Emails:
- Business:
- lbible@ufl.edu
Addresses:
- Business Street:
-
PO Box 100286
GAINESVILLE FL 32610